Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Oliver, Howes"'
Autor:
Chiara Prodani, Elaine E. Irvine, Alessandro Sardini, Hannah J. Gleneadie, Andrew Dimond, Mathew Van de Pette, Rosalind John, Michelle Kokkinou, Oliver Howes, Dominic J. Withers, Mark A. Ungless, Matthias Merkenschlager, Amanda G. Fisher
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract We tracked the consequences of in utero protein restriction in mice throughout their development and life course using a luciferase-based allelic reporter of imprinted Cdkn1c. Exposure to gestational low-protein diet (LPD) results in the ina
Externí odkaz:
https://doaj.org/article/81d158cc89d44bcea82892374ccb7f0f
Autor:
Lucia Maccioni, Carranza Mellana Michelle, Ludovica Brusaferri, Erica Silvestri, Alessandra Bertoldo, Julia J. Schubert, Maria A. Nettis, Valeria Mondelli, Oliver Howes, Federico E. Turkheimer, Michel Bottlaender, Benedetta Bodini, Bruno Stankoff, Marco L. Loggia, Mattia Veronese
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionRecent evidence suggests the blood-to-brain influx rate (K1) in TSPO PET imaging as a promising biomarker of blood–brain barrier (BBB) permeability alterations commonly associated with peripheral inflammation and heightened immune activ
Externí odkaz:
https://doaj.org/article/760dc5ff829c4c71a2186e6159860f14
Autor:
Oliver Cousins, Julia J. Schubert, Avinash Chandra, Mattia Veronese, Polena Valkimadi, Byron Creese, Zunera Khan, Ryan Arathimos, Adam Hampshire, Ivana Rosenzweig, Clive Ballard, Anne Corbett, Dag Aasland, Latha Velayudhan, Michael O’Neill, David Collier, Ramla Awais, Kerstin Sander, Erik Årstad, Oliver Howes, Federico Turkheimer, Angela Hodges
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background Microglia are increasingly understood to play an important role in the pathogenesis of Alzheimer’s disease. The rs75932628 (p.R47H) TREM2 variant is a well-established risk factor for Alzheimer’s disease. TREM2 is a microglial
Externí odkaz:
https://doaj.org/article/dcda124d1d09457494573f17556489a7
Publikováno v:
Biological Psychiatry Global Open Science, Vol 3, Iss 1, Pp 22-32 (2023)
Patients with schizophrenia often undergo a prodromal phase prior to diagnosis. Given the absence of significant therapeutic improvements, attention has recently shifted to the possibility of intervention during this early stage to delay or diminish
Externí odkaz:
https://doaj.org/article/f477267d3b334760a9d6194139343ab3
Autor:
Nora Penzel, Rachele Sanfelici, Linda A. Antonucci, Linda T. Betz, Dominic Dwyer, Anne Ruef, Kang Ik K. Cho, Paul Cumming, Oliver Pogarell, Oliver Howes, Peter Falkai, Rachel Upthegrove, Stefan Borgwardt, Paolo Brambilla, Rebekka Lencer, Eva Meisenzahl, Frauke Schultze-Lutter, Marlene Rosen, Theresa Lichtenstein, Lana Kambeitz-Ilankovic, Stephan Ruhrmann, Raimo K. R. Salokangas, Christos Pantelis, Stephen J. Wood, Boris B. Quednow, Giulio Pergola, Alessandro Bertolino, Nikolaos Koutsouleris, Joseph Kambeitz, the PRONIA Consortium
Publikováno v:
npj Schizophrenia, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Continued cannabis use (CCu) is an important predictor for poor long-term outcomes in psychosis and clinically high-risk patients, but no generalizable model has hitherto been tested for its ability to predict CCu in these vulnerable patient
Externí odkaz:
https://doaj.org/article/5423228607174dbd91d07c33026cc7b3
Autor:
Daniela Ribeiro, William Hallett, Oliver Howes, Robert McCutcheon, Matthew M. Nour, Adriana A. S. Tavares
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Introduction Q.Clear is a Bayesian penalised likelihood (BPL) reconstruction algorithm available on General Electric (GE) Positron Emission Tomography (PET)-Computed Tomography (CT) and PET-Magnetic Resonance (MR) scanners. This algorithm is
Externí odkaz:
https://doaj.org/article/989057b320404bee982dd38f7a29e8ee
Autor:
Paul Allen, Emily J. Hird, Natasza Orlov, Gemma Modinos, Matthijs Bossong, Mathilde Antoniades, Carly Sampson, Matilda Azis, Oliver Howes, James Stone, Jesus Perez, Matthew Broome, Antony A. Grace, Philip McGuire
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Preclinical rodent models suggest that psychosis involves alterations in the activity and glutamatergic function in the hippocampus, driving dopamine activity through projections to the striatum. The extent to which this model applies to the
Externí odkaz:
https://doaj.org/article/8f67679a12be4d6f8abeb8495cd43e50
Autor:
Beata R. Godlewska, Amedeo Minichino, Uzay Emir, Ilinca Angelescu, Belinda Lennox, Masa Micunovic, Oliver Howes, Philip J. Cowen
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Abnormalities in glutamate neurotransmission are linked to psychotic symptoms and cognitive dysfunction in schizophrenia. magnetic resonance spectroscopy (MRS) provides an acceptable means of measuring glutamate in the human brain but findin
Externí odkaz:
https://doaj.org/article/d961cb2a80f5463ea309679c732eb3ac
Autor:
Alice Petty, Xiaoying Cui, Asad Ali, Zilong Du, Sunil Srivastav, James P. Kesby, Deniz Kirik, Oliver Howes, Darryl Eyles
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract An increase in dopamine (DA) synthesis capacity in the dorsal striatum (DS) during the prodromal stage of schizophrenia becomes more pronounced as patients progress to the full disorder. Understanding this progression is critical to interven
Externí odkaz:
https://doaj.org/article/041501d82fe64bce8596a7893fcb044b
Autor:
David Erritzoe, Beata R. Godlewska, Gaia Rizzo, Graham E. Searle, Claudio Agnorelli, Yvonne Lewis, Abhishekh H. Ashok, Alessandro Colasanti, Iro Boura, Chloe Farrell, Hollie Parfitt, Oliver Howes, Jan Passchier, Roger N. Gunn, Marios Politis, David J. Nutt, Philip J. Cowen, Gitte M. Knudsen, Eugenii A. Rabiner
Publikováno v:
Biological Psychiatry. 93:1089-1098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c81c6dc56f75c7371bfdb6f3a671606b
https://doi.org/10.1016/j.biopsych.2022.10.012
https://doi.org/10.1016/j.biopsych.2022.10.012