Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Oliver, Hartley"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The chemokine receptor CCR5 is known to exist in cell surface subpopulations that differ in their capacity to engage ligands. One proposed explanation for this phenomenon is the presence of CCR5 species with different levels of post-translat
Externí odkaz:
https://doaj.org/article/6d3cda58a59b4034a4d7659b714e5dd5
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/8d73a97bdc914527a21fdc3407d66503
Autor:
Maria Vono, Beatris Mastelic-Gavillet, Elodie Mohr, Malin Östensson, Josefine Persson, Thorunn A. Olafsdottir, Sylvain Lemeille, David Pejoski, Oliver Hartley, Dennis Christensen, Peter Andersen, Arnaud M. Didierlaurent, Ali M. Harandi, Paul-Henri Lambert, Claire-Anne Siegrist
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionC-type lectin receptor (CLR) agonists emerged as superior inducers of primary B cell responses in early life compared with Toll-like receptor (TLR) agonists, while both types of adjuvants are potent in adults.MethodsHere, we explored the
Externí odkaz:
https://doaj.org/article/09b8465345674f77b4bc4ccc4f8b2f3e
Publikováno v:
CHIMIA, Vol 75, Iss 6, Pp 489-494 (2021)
Numerous members of the human G protein-coupled receptor (GPCR) superfamily are receptors of therapeutic interest. GPCRs are considered to be highly tractable for drug discovery, representing the targets of approximately one-third of currently licens
Externí odkaz:
https://doaj.org/article/32b88024a4dc49d18004e1d67665839d
Autor:
Nicolas Vuilleumier, Panagiotis Antiochos, Pedro Marques‐Vidal, Sabrina Pagano, Julien Virzi, Nathalie Satta, Oliver Hartley, Hubert Gaertner, Karim J Brandt, Fabienne Burger, Fabrizio Montecucco, Gerard Waeber, François Mach, Peter Vollenweider
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)
Abstract Objectives Autoantibodies against apolipoprotein A1 (anti‐apoA1 IgGs) and its C‐terminal region (cter apoA1) have emerged as an independent biomarker for cardiovascular disease. Cter apoA1 mimetic peptides were shown to reverse the delet
Externí odkaz:
https://doaj.org/article/2892c10f08944421a354e62eb524d99f
Autor:
Jale Yuzugulen, Julie A. Douthwaite, Elizabeth G. Wood, Inmaculada C. Villar, Nimesh S. A. Patel, James Jegard, Hubert Gaertner, Irène Rossitto-Borlat, Keith Rose, Oliver Hartley, Pedro R. Cutillas, Amrita Ahluwalia, Roger Corder
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Endothelin-1 (ET-1) is involved in the pathogenesis of cardiac and renal diseases, and in the progression of tumour growth in cancer, but current diagnosis and treatment remain inadequate. Peptides derived from the 212 amino acid precursor p
Externí odkaz:
https://doaj.org/article/c88405d4ef9a4272ab9b01473d274a6f
Autor:
Beryl Mazel-Sanchez, Chengyue Niu, Nathalia Williams, Michael Bachmann, Hélèna Choltus, Filo Silva, Véronique Serre-Beinier, Wolfram Karenovics, Justyna Iwaszkiewicz, Vincent Zoete, Laurent Kaiser, Oliver Hartley, Bernhard Wehrle-Haller, Mirco Schmolke
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Influenza A virus (IAV) enters host cells mostly through clathrin-dependent receptor-mediated endocytosis. A single bona fide entry receptor protein supporting this entry mechanism remains elusive. Here we performed proximity ligation of biotin to ho
Publikováno v:
Swiss Medical Weekly, Vol 148, Iss 0304 (2018)
Of the two million people estimated to be newly infected with human immunodeficiency virus (HIV) every year, 95% live in poorer regions of the world where effective HIV treatment is not universally available. Strategies to reduce the spread of HIV in
Externí odkaz:
https://doaj.org/article/1374713e782748839de35b0c2369db25
Autor:
Pierre Cosson, Oliver Hartley
Publikováno v:
CHIMIA, Vol 70, Iss 12 (2016)
After several decades of optimization, phage display technology enables the routine isolation and production of recombinant monoclonal antibodies in vitro. As such it has the potential to provide the academic community with a vast, inexpensive and re
Externí odkaz:
https://doaj.org/article/a77468c8239e49f2935a363e43c55cf0
Autor:
Sabrina Pagano, Hubert Gaertner, Fabrice Cerini, Tiphaine Mannic, Nathalie Satta, Priscila Camillo Teixeira, Paul Cutler, François Mach, Nicolas Vuilleumier, Oliver Hartley
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132780 (2015)
Cardiovascular disease (CVD) is the leading cause of death worldwide and new approaches for both diagnosis and treatment are required. Autoantibodies directed against apolipoprotein A-I (ApoA-I) represent promising biomarkers for use in risk stratifi
Externí odkaz:
https://doaj.org/article/d71fe6cec5384c9a8e8759ee64e05c43