Výsledky vyhledávání - "Oliver, Hardt"

Akademický článek

Infusing zeta inhibitory peptide into the perirhinal cortex of rats abolishes long-term object recognition memory without affecting novel object location recognition

Autor: Keanan Augereau, Paola V. Migues, Oliver Hardt

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 16 (2022)

Infusing the amnesic agent zeta inhibitory peptide (ZIP) into the dorsal hippocampus disrupts established long-term object location recognition memory without affecting object identity recognition, which likely depends on the perirhinal cortex. Here,

Externí odkaz: https://doaj.org/article/332f18d5f1c241c595be839cf7b272f8

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Specific behaviors during auditory fear conditioning and postsynaptic expression of AMPA receptors in the basolateral amygdala predict interindividual differences in fear generalization in male rats

Autor: Bruno José Moraes, Oliver Hardt

Publikováno v: Learning & Memory. 30:74-84

Auditory fear conditioning in rats is a widely used method to study learning, memory, and emotional responding. Despite procedural standardizations and optimizations, there is substantial interindividual variability in fear expression during test, no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4b195f8f74e14b5961042cf72874177
https://doi.org/10.1101/lm.053612.122

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Akademický článek

Terminological and Epistemological Issues in Current Memory Research

Autor: Oliver Hardt, Wayne S. Sossin

Publikováno v: Frontiers in Molecular Neuroscience, Vol 12 (2020)

A number of observations in recent years demonstrates that across all levels of organization, memory is inherently fluid. On the cognitive-behavioral level, the innocent act of remembering can irrevocably alter the contents of established long-term m

Externí odkaz: https://doaj.org/article/b28cc20a040744eaa719d1812459e5c6

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Akademický článek

Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer’s Disease

Publikováno v: Cell Reports, Vol 29, Iss 11, Pp 3592-3604.e5 (2019)

Summary: A key knowledge gap blocking development of effective therapeutics for Alzheimer’s disease (AD) is the lack of understanding of how amyloid beta (Aβ) peptide and pathological forms of the tau protein cooperate in causing disease phenotype

Externí odkaz: https://doaj.org/article/5c607706c23f4f7d92a682e925ca0372

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Imbalance of flight–freeze responses and their cellular correlates in the Nlgn3−/y rat model of autism

Autor: Natasha J. Anstey, Vijayakumar Kapgal, Shashank Tiwari, Thomas C. Watson, Anna K. H. Toft, Owen R. Dando, Felicity H. Inkpen, Paul S. Baxter, Zrinko Kozić, Adam D. Jackson, Xin He, Mohammad Sarfaraz Nawaz, Aiman Kayenaat, Aditi Bhattacharya, David J. A. Wyllie, Sumantra Chattarji, Emma R. Wood, Oliver Hardt, Peter C. Kind

Publikováno v: Anstey, N J, Kapgal, V, Tiwari, S, Watson, T C, Toft, A K H, Dando, O R, Inkpen, F H, Baxter, P S, Kozic, Z, Jackson, A D, He, X, Nawaz, M S, Kayenaat, A, Bhattacharya, A, Wyllie, D J A, Chattarji, S, Wood, E R, Hardt, O & Kind, P C 2022, ' Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3-/y rat model of autism ', Molecular Autism, vol. 13, 34 . https://doi.org/10.1186/s13229-022-00511-8

BackgroundMutations in the postsynaptic transmembrane protein neuroligin-3 are highly correlative with autism spectrum disorders (ASDs) and intellectual disabilities (IDs). Fear learning is well studied in models of these disorders, however differenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c236db287e28b698524b9c96f2a988
https://doi.org/10.1186/s13229-022-00511-8

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Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3

Autor: Natasha J, Anstey, Vijayakumar, Kapgal, Shashank, Tiwari, Thomas C, Watson, Anna K H, Toft, Owen R, Dando, Felicity H, Inkpen, Paul S, Baxter, Zrinko, Kozić, Adam D, Jackson, Xin, He, Mohammad Sarfaraz, Nawaz, Aiman, Kayenaat, Aditi, Bhattacharya, David J A, Wyllie, Sumantra, Chattarji, Emma R, Wood, Oliver, Hardt, Peter C, Kind

Publikováno v: Molecular autism. 13(1)

Mutations in the postsynaptic transmembrane protein neuroligin-3 are highly correlative with autism spectrum disorders (ASDs) and intellectual disabilities (IDs). Fear learning is well studied in models of these disorders, however differences in fear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2eba4b5c5f50b8abb5c2bf2ef1b0ffb6
https://pubmed.ncbi.nlm.nih.gov/35850732

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The Black Box effect: sensory stimulation after learning interferes with the retention of long-term object location memory in rats

Autor: Daisy Arkell, Emma R. Wood, Oliver Hardt, Isabelle Groves

Publikováno v: Learn Mem
Arkell, D, Groves, I, Wood, E R & Hardt, O 2021, ' The Black Box effect: sensory stimulation after learning interferes with the retention of long-term object location memory in rats ', Learning & Memory . https://doi.org/10.1101/lm.053256.120

Reducing sensory experiences during the period that immediately follows learning improves long-term memory retention in healthy humans, and even preserves memory in patients with amnesia. To date, it is entirely unclear why this is the case, and iden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28797e6616082a7353affc0d8230970a
https://pubmed.ncbi.nlm.nih.gov/34526383

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