Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Oliver, Clewes"'
Publikováno v:
Stem Cell Reviews
Here we show that epidermal neural crest stem cell (EPI-NCSC) transplants in the contused spinal cord caused a 24% improvement in sensory connectivity and a substantial recovery of touch perception. Furthermore we present a novel method for the ex vi
Autor:
Raheleh Masoudi, David Dawbarn, Shelley J Allen, Promila Pagadala, Maria S. Ioannou, Kenneth E. Neet, Michael D. Coughlin, Oliver Clewes, Margaret Fahnestock
Publikováno v:
Journal of Biological Chemistry. 284:18424-18433
Nerve growth factor (NGF) is produced as a precursor called pro-nerve growth factor (proNGF), which is secreted by many tissues and is the predominant form of NGF in the central nervous system. In Alzheimer disease brain, cholinergic neurons degenera
Autor:
Alla, Narytnyk, Bernard, Verdon, Andrew, Loughney, Michele, Sweeney, Oliver, Clewes, Michael J, Taggart, Maya, Sieber-Blum
Publikováno v:
Stem Cell Reviews
Here we provide a protocol for the directed differentiation of hEPI-NCSC into midbrain dopaminergic neurons, which degenerate in Parkinson’s disease. hEPI-NCSC are neural crest-derived multipotent stem cells that persist into adulthood in the bulge
Autor:
Oliver Clewes, Maya Sieber-Blum
Publikováno v:
Neural Crest Stem Cells: Breakthroughs and Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff7936e749d4ee282c8da9ee2434e230
https://doi.org/10.1142/9789814343817_0005
https://doi.org/10.1142/9789814343817_0005
Autor:
Oliver Clewes, Maya Sieber-Blum, Alan Mackay, John Burn, James A. A. Langtry, Alan Ashworth, Christopher J. Lord, Neil Rajan, Richard Elliott, Jorge S. Reis-Filho
Publikováno v:
Oncogene
Individuals with germline mutations in the tumour suppressor gene CYLD are at high risk of developing disfiguring cutaneous appendageal tumours, the defining tumour being the highly organised cylindroma. Here, we analysed CYLD mutant tumour genomes b
Publikováno v:
The FASEB Journal. 24
Autor:
Oliver Clewes, Shelley J Allen, Caterina Catania, Heon Seok, Judy J. Watson, David Dawbarn, SJ Tyler, Kwangwook Cho, Mark S. Fahey
Publikováno v:
Journal of Neurochemistry.
Nerve growth factor (NGF) promotes cell survival via binding to the tyrosine kinase receptor A (TrkA). Its precursor, proNGF, binds to p75(NTR) and sortilin receptors to initiate apoptosis. Current disagreement exists over whether proNGF acts neurotr
Publikováno v:
Stem Cell Reviews
We show that neural crest stem cells affect mouse hair follicle development. During embryogenesis hair follicle induction is regulated by complex reciprocal and functionally redundant signals between epidermis and dermis, which remain to be fully und
Autor:
Alison Murdoch, Oliver Clewes, Andrew Loughney, Kevin R. Gillinder, Maya Sieber-Blum, Alla Narytnyk
Publikováno v:
Stem Cell Reviews
Here we describe the isolation, characterisation and ex-vivo expansion of human epidermal neural crest stem cells (hEPI-NCSC) and we provide protocols for their directed differentiation into osteocytes and melanocytes. hEPI-NCSC are neural crest-deri