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A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.

Autor: Marini, Eleonora¹ (AUTHOR), Olivença, Carmen¹ (AUTHOR), Ramalhete, Sara¹ (AUTHOR), Aguirre, Andrea Martinez² (AUTHOR), Ingle, Patrick³ (AUTHOR), Melo, Manuel N.¹ (AUTHOR), Antunes, Wilson¹ (AUTHOR), Minton, Nigel P.³ (AUTHOR), Hernandez, Guillem¹ (AUTHOR), Cordeiro, Tiago N.¹ (AUTHOR), Sorg, Joseph A.² (AUTHOR), Serrano, Mónica¹ (AUTHOR), Henriques, Adriano O.¹ (AUTHOR) aoh@itqb.unl.pt

Publikováno v: PLoS Pathogens. 11/13/2023, Vol. 19 Issue 11, p1-37. 37p.

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The Impact of YabG Mutations on Clostridioides difficile Spore Germination and Processing of Spore Substrates.

Autor: Osborne, Morgan S., Brehm, Joshua N., Olivença, Carmen, Cochran, Alicia M., Serrano, Mónica, Henriques, Adriano O., Sorg, Joseph A.

Publikováno v: Molecular Microbiology; Oct2024, Vol. 122 Issue 4, p534-548, 15p

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Functional characterization of a cysteine protease essential for the assembly of the Clostridioides difficile spore surface layers

Autor: Olivença, Carmen Maria Antunes

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Clostridioides difficile is a Gram-positive, strict anaerobe, sporeforming organism, and the leading cause of a range of intestinal diseases linked to antibiotic therapy. C. difficile infection begins with the ingestion of spores that are also the ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::58a0cb4767abcbaf38cac2ece9c6e509
https://hdl.handle.net/10362/132664

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Akademický článek

The impact of YabG mutations on C. difficile spore germination and processing of spore substrates.

Autor: Osborne MS; Department of Biology, Texas A&M University, College Station, TX 77845, USA., Brehm JN; Department of Biology, Texas A&M University, College Station, TX 77845, USA., Olivença C; Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal., Cochran AM; Department of Biology, Texas A&M University, College Station, TX 77845, USA., Serrano M; Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal., Henriques AO; Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal., Sorg JA; Department of Biology, Texas A&M University, College Station, TX 77845, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 10. Date of Electronic Publication: 2024 Jun 10.

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