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Autor:
Dal Forno, Gean M, Latocheski, Eloah, Beatriz Machado, Ana, Becher, Julie, Dunsmore, Lavinia, St John, Albert L, Oliveira, Bruno L, Navo, Claudio D, Jiménez-Osés, Gonzalo, Fior, Rita, Domingos, Josiel B, Bernardes, Gonçalo JL
The ability to control the activation of prodrugs by transition metals has been shown to have great potential for controlled drug release in cancer cells. However, the strategies developed so far promote the cleavage of C-O or C-N bonds, which limits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::9e51619d46514332391b5d3600820bb9
https://www.repository.cam.ac.uk/handle/1810/350003
https://www.repository.cam.ac.uk/handle/1810/350003
Autor:
Sousa, Bárbara B., de Almeida, Cátia Rebelo, Barahona, Ana F., Lopes, Raquel, Martins-Logrado, Ana, Cavaco, Marco, Neves, Vera, Carvalho, Luís A.R., Labaõ-Almeida, Carlos, Coelho, Ana R., Bento, Marta Leal, Lopes, Ricardo M.R.M., Oliveira, Bruno L., Castanho, Miguel A.R.B., Neumeister, Peter, Deutsch, Alexander, Vladimer, Gregory I., Krall, Nikolaus, Joaõ, Cristina, Corzana, Francisco, Seixas, Joaõ D., Fior, Rita, Bernardes, Gonçalo J.L., 0000-0002-0938-9038, 0000-0002-2989-7208, 0000-0001-7891-7562, 0000-0003-4205-7585, 0000-0001-5597-8127, 0000-0001-6594-8917
Bruton's tyrosine kinase (BTK) is a member of the TEC-family kinases and crucial for the proliferation and differentiation of B-cells. We evaluated the therapeutic potential of a covalent inhibitor (JS25) with nanomolar potency against BTK and with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe3f9b0697dca6740a74f3e7bf89647
https://www.repository.cam.ac.uk/handle/1810/343251
https://www.repository.cam.ac.uk/handle/1810/343251
Publikováno v:
In Coordination Chemistry Reviews October 2013 257(19-20):2689-2704
Autor:
Oliveira, Bruno L., Moreira, Irina S., Fernandes, Pedro A., Ramos, Maria J., Santos, Isabel, Correia, João D.G.
Publikováno v:
In Journal of Molecular Graphics and Modelling September 2013 45:13-25
Autor:
Zwicker, Vincent E.1, Oliveira, Bruno L.2,3, Yeo, Jia Hao1,4, Fraser, Stuart T.4, Bernardes, Gonçalo J. L.2,3, New, Elizabeth J.1, Jolliffe, Katrina A.1 kate.jolliffe@sydney.edu.au
Publikováno v:
Angewandte Chemie. 3/4/2019, Vol. 131 Issue 10, p3119-3123. 5p.
Autor:
Oliveira, Bruno L., Raposinho, Paula D., Mendes, Filipa, Santos, Isabel C., Santos, Isabel, Ferreira, António, Cordeiro, Carlos, Freire, Ana P., Correia, João D.G.
Publikováno v:
In Journal of Organometallic Chemistry 2011 696(5):1057-1065
Autor:
Zawada, Zbigniew, Guo, Zijian, Oliveira, Bruno L, Navo, Claudio D, Li, He, Cal, Pedro MSD, Corzana, Francisco, Jiménez-Osés, Gonzalo, Bernardes, Gonçalo JL
Strained alkenes and alkynes are the predominant dienophiles used in inverse electron demand Diels-Alder (IEDDA) reactions. However, their instability, cross-reactivity, and accessibility are problematic. Unstrained dienophiles, although physiologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d14f8409b934d31ff356e753eb0fb3
Autor:
Sun, Shuang1, Oliveira, Bruno L.1, Jiménez‐Osés, Gonzalo2, Bernardes, Gonçalo J. L.1,3 gb453@cam.ac.ukgbernardes@medicina.ulisboa.pt
Publikováno v:
Angewandte Chemie. 11/26/2018, Vol. 130 Issue 48, p16058-16061. 4p.
Autor:
Oliveira, Bruno L.1 brunodlo@yahoo.com.br, Souza, Rodrigo M.2 rodrigoms_uca@ymail.com, Filho, Jorge P. Silva3 jpintodasilvafilho2@gmail.com, Gomes, Levy C.4 levy.gomes@uvv.br, Fernandes, Luiz F. Loureiro3 luiz.ufes@gmail.com
Publikováno v:
Neotropical Ichthyology. 2018, Vol. 16 Issue 1, p1-8. 8p.