Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Olive T. W. Li"'
Autor:
Tung Gia Phan, Nguyen Phung Vo, Ákos Boros, Péter Pankovics, Gábor Reuter, Olive T W Li, Chunling Wang, Xutao Deng, Leo L M Poon, Eric Delwart
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72787 (2013)
Birds are frequent sources of emerging human infectious diseases. Viral particles were enriched from the feces of 51 wild urban pigeons (Columba livia) from Hong Kong and Hungary, their nucleic acids randomly amplified and then sequenced. We identifi
Externí odkaz:
https://doaj.org/article/722aa6df205b414a9409cd1a86529318
Autor:
Malik Peiris, Leo L.M. Poon, Li-Meng Yan, Sophie A. Valkenburg, Ranawaka A.P.M. Perera, Olive T. W. Li, Chek M. Poh
Publikováno v:
Virology. 525:73-82
The limited protection of current commerical vaccines necessitates the investigation of novel vaccine strategies for unpredictable outbreaks. To investigate the feasibility of using vaccines derived from Group 1 influenza A virus to induce broadly cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2ff543badd34dd97febdf64c343750
https://doi.org/10.1016/j.virol.2018.09.007
https://doi.org/10.1016/j.virol.2018.09.007
Autor:
Olive T. W. Li, Maireid B. Bull, Malik Peiris, Leo L.M. Poon, Athena P. Y. Li, Thomas A. Waldmann, Liyanage P. Perera, Sophie A. Valkenburg
Publikováno v:
Vaccine
There is a diverse array of influenza viruses which circulate between different species, reassort and drift over time. Current seasonal influenza vaccines are ineffective in controlling these viruses. We have developed a novel universal vaccine which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f62df6788c97e43943e7517354fafe
https://doi.org/10.1016/j.vaccine.2018.06.007
https://doi.org/10.1016/j.vaccine.2018.06.007
Autor:
Olive T W Li, Michael C W Chan, Cynthia S W Leung, Renee W Y Chan, Yi Guan, John M Nicholls, Leo L M Poon
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5658 (2009)
Amongst all the internal gene segments (PB2. PB1, PA, NP, M and NS), the avian PB1 segment is the only one which was reassorted into the human H2N2 and H3N2 pandemic strains. This suggests that the reassortment of polymerase subunit genes between mam
Externí odkaz:
https://doaj.org/article/775ebfc9ae7e4f5f9e7570b7305fbe07
Autor:
Sophie A. Valkenburg, Rebecca L. Y. Fan, John M. Nicholls, J. S. Malik Peiris, Olive T. W. Li, Leo L.M. Poon, Raul Rabadan, Chloe K.S. Wong
Publikováno v:
Journal of Virology. 89:10762-10773
Seasonal influenza epidemics and occasional pandemics threaten public health worldwide. New alternative strategies for generating recombinant viruses with vaccine potential are needed. Interestingly, influenza viruses circulating in different hosts h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b308cabb069e6e3664abe43178e92568
https://doi.org/10.1128/jvi.01443-15
https://doi.org/10.1128/jvi.01443-15
Publikováno v:
Virology. :545-555
Sequence analyses of influenza PB2 sequences indicate that the 627 position almost exclusively contains either lysine (K) or glutamic acid (E), suggesting a high sequence constraint at this genetic marker. Here, we used a site-directed random mutagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ef9fccb1fd84d0d54016da8488627c
Autor:
Malik Peiris, Chloe K.S. Wong, Gary C.H. Tsang, Olive T. W. Li, Kwok-Hung Chan, Leo L.M. Poon
Publikováno v:
Journal of Medical Virology. 86:2171-2176
Contemporary influenza B viruses are classified into two groups known as Yamagata and Victoria lineages. The co-circulation of two viral lineages in recent years urges for a robust and simple diagnostic test for detecting influenza B viruses and for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce6365dfa04329817a7d3173ce779636
https://doi.org/10.1002/jmv.23955
https://doi.org/10.1002/jmv.23955
Autor:
J. S. Malik Peiris, Olive T. W. Li, Leo L.M. Poon, Thomas A. Waldmann, Polly W.Y. Mak, Chris Ka Pun Mok, Yi Guan, Liyanage P. Perera, Sophie A. Valkenburg, John M. Nicholls
Publikováno v:
Proceedings of the National Academy of Sciences. 111:5676-5681
Session - Medical Sciences
Current influenza vaccines are ineffective against novel viruses and the source or the strain of the next outbreak of influenza is unpredictable; therefore, establishing universal immunity by vaccination to limit the i
Current influenza vaccines are ineffective against novel viruses and the source or the strain of the next outbreak of influenza is unpredictable; therefore, establishing universal immunity by vaccination to limit the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe65af8b8d8c4cd0bc9cd6661237f52b
https://doi.org/10.1073/pnas.1403684111
https://doi.org/10.1073/pnas.1403684111
Publikováno v:
Influenza and Other Respiratory Viruses
Objectives Reassortment of influenza A viruses can give rise to viral ribonucleoproteins (vRNPs) with elevated polymerase activity and the previous three pandemic influenza viruses contained reassorted vRNPs of different origins. These suggest that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68e43fa5398ee63e131dc6f21997c3b
http://europepmc.org/articles/PMC3823691
http://europepmc.org/articles/PMC3823691
Autor:
Olive T. W. Li, Chloe K.S. Wong, Leo L.M. Poon, Michael C. W. Chan, Yi Guan, Hongbo Zhu, Joseph S. M. Peiris, Yin Hung C. Leung
Publikováno v:
Clinical Chemistry
Clinical Chemistry; Vol 59
Clinical Chemistry; Vol 59
BACKGROUNDA novel subtype of influenza A virus (H7N9) was recently identified in humans. The virus is a reassortant of avian viruses, but these human isolates contain mutations [hemagglutinin (HA) Q226L and PB2 E627K] that might make it easier for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7552275a28151022c12cef6421b1a00