Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Oligopeptides/chemistry"'
Autor:
Peter H.G.M. Willems, Jan A.M. Smeitink, Lisanne M.P.E. van Oppen, Werner J.H. Koopman, Roland Brock, Jan Pille, Christiaan Stuut, Jan C. M. van Hest, Marleen H. M. E. van Stevendaal, Lisa N. van der Vorm
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, 137, 175-184. Elsevier
European Journal of Pharmaceutics and Biopharmaceutics, 137, 175-184
European Journal of Pharmaceutics and Biopharmaceutics, 137, pp. 175-184
European Journal of Pharmaceutics and Biopharmaceutics, 137, 175-184
European Journal of Pharmaceutics and Biopharmaceutics, 137, pp. 175-184
Contains fulltext : 202255.pdf (Publisher’s version ) (Closed access) Elastin-like polypeptide (ELP) nanoparticles are a versatile platform for targeted drug delivery. As for any type of nanocarrier system, an important challenge remains the abilit
Autor:
Fujiwara, Y., Yamanashi, Y., Fujimura, A., Sato, Y., Kujirai, T., Kurumizaka, H., Kimura, Hiroshi, Yamatsugu, K., Kawashima, S. A., Kanai, M.
Publikováno v:
Proc Natl Acad Sci U S A
Chemical modifications of histones, such as lysine acetylation and ubiquitination, play pivotal roles in epigenetic regulation of gene expression. Methods to alter the epigenome thus hold promise as tools for elucidating epigenetic mechanisms and as
Autor:
Anja Seckinger, Giorgio Mori, Volker Martin, Anna Luise Grab, Elisabetta Ada Cavalcanti-Adam, Slobodan Vukicevic, Francesca Posa, Dirk Hose
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
We report on the covalent immobilization of bone morphogenetic protein 6 (BMP-6) and its co-presentation with integrin ligands on a nanopatterned platform to study cell adhesion and signaling responses which regulate the transdifferentiation of myobl
Autor:
Joana Crisóstomo, Sílvia J. Bidarra, Cristina C. Barrias, Pedro L. Granja, Raquel Seiça, Ana Margarida Pereira, Ana Cristina Gonçalves, Jorge Fj Coelho
Publikováno v:
Journal of Applied Biomaterials & Functional Materials, Vol 17 (2019)
Introduction: The success of a bioartificial pancreas crucially depends on ameliorating encapsulated beta cells survival and function. By mimicking the cellular in vivo niche, the aim of this study was to develop a novel model for beta cells encapsul
Publikováno v:
Chembiochem
ChemBioChem, 18(5). Wiley-VCH Verlag
ChemBioChem, 18(5). Wiley-VCH Verlag
The potential of the fluorescent protein scaffold in controlling peptide sequence functionality is illustrated via the exploration of fluorescent proteins as novel probes for targeting of integrins. A library of fluorescent mCitrine proteins with RGD
Autor:
Lagard, Camille, Chevillard, Lucie, Guillemyn, Karel, Risede, Patricia, Laplanche, Jean-Louis, Spetea, Mariana, Ballet, Steven, Megarbane, Bruno
Drugs able to treat both nociceptive and neuropathic pain effectively without major side effects are lacking. We developed a bifunctional peptide-based hybrid (KGNOP1) that structurally combines a mu-opioid receptor agonist (KGOP1) with antinocicepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3848::72dc760238222de4323c873a3bcad65a
https://doi.org/10.1097/j.pain.0000000000000790
https://doi.org/10.1097/j.pain.0000000000000790
Autor:
Claudiane Maria Barbosa, Friederike Kemplin, Joachim Jankowski, Michael Bader, Frederico B. De Sousa, Daniel C. Villela, Roberto Queiroga Lautner, Maria José Campagnole-Santos, Fabiana Alves, Almir S. Martins, Rodrigo A. Fraga-Silva, Gisele Maia, Adriano Marçal Pimenta, Vera Jankowski, Robson A.S. Santos, Rubén D. Sinisterra, Thiago Verano-Braga, Janaina F Braga, Andréia Carvalho Alzamora, Antonio A B Peluso, Everton Rocha Soares, Frank Kjeldsen, Fabiana P. Costa-Fraga, Daisy Motta-Santos, Anderson J. Ferreira, Silvia Q Savergnini, Renata D. Paula, Neiva Caldeira Silva, Danielle G. Passos-Silva, Natalia Alenina, Aline C. Oliveira, Mohan K. Raizada
Publikováno v:
Lautner, R Q, Villela, D C, Fraga-Silva, R A, Silva, N C, Verano-Braga, T, Costa-Fraga, F, Jankowski, J, Jankowski, V, De Sousa, F B, Alzamora, A C, Soares, E R, Barbosa, C M, Kjeldsen, F, Oliveira, A C, Braga, J F, Savergnini, S Q, Etelvino, G M, Peluso, A A B, Passos-Silva, D G, Ferreira, A J, Alves, F, Martins, A S, Raizada, M K, Paula, R D, Motta-Santos, D, Klempin, F, Pimenta, A M C, Alenina, N, Sinisterra, R D M, Bader, M, Campagnole-Santos, M J & Santos, R A 2013, ' Discovery and Characterization of Alamandine, a Novel Component of the Renin-Angiotensin System ', Circulation Research, vol. 112, no. 8, pp. 1104-1111 . https://doi.org/10.1161/CIRCRESAHA.113.301077
Circulation Research; Vol 112
Circulation Research; Vol 112
Rationale: The renin–angiotensin system (RAS) is a key regulator of the cardiovascular system, electrolyte, and water balance. Here, we report identification and characterization of alamandine, a new heptapeptide generated by catalytic action of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26de69d1ea4b004a964f0176d773f79
https://portal.findresearcher.sdu.dk/da/publications/5868a41e-dbfd-4841-b1f0-89d09bbe5038
https://portal.findresearcher.sdu.dk/da/publications/5868a41e-dbfd-4841-b1f0-89d09bbe5038
Autor:
J. Carlos Rodríguez-Cabello, Martijn van Griensven, Paulo C. Bessa, Asmita Banerjee, Raul Machado, António M. Cunha, Rui L. Reis, Sylvia Nürnberger, Heinz Redl, Daniela Dopler, Margarida Casal
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Elastin-like polymers are a new type of protein-based polymers that display interesting properties in the biomaterial field. Bone morphogenetic proteins (BMPs) are cytokines with a strong ability to promote new bone formation. In this work, we explor
Autor:
Bruno Kieffer, L. Rochet, Gaëtan L.A. Mislin, V. Schons, R. A. Atkinson, Isabelle J. Schalk, Christophe Hennard, R. Graff, Mohamed A. Abdallah, C. Dugave
Publikováno v:
Biochemistry
Biochemistry, American Chemical Society, 2005, 44 (43), pp.14069-79. ⟨10.1021/bi051155s⟩
Biochemistry, American Chemical Society, 2005, 44, pp.14069-79
Biochemistry, 2005, 44 (43), pp.14069-79. ⟨10.1021/bi051155s⟩
Biochemistry, American Chemical Society, 2005, 44 (43), pp.14069-79. ⟨10.1021/bi051155s⟩
Biochemistry, American Chemical Society, 2005, 44, pp.14069-79
Biochemistry, 2005, 44 (43), pp.14069-79. ⟨10.1021/bi051155s⟩
0006-2960 (Print) Journal Article; Under iron limitation, Pseudomonas aeruginosa ATCC 15692 secretes a major siderophore, pyoverdine I (PvdI). This molecule chelates iron in the extracellular medium and shuttles it into the cells via a specific outer
Publikováno v:
Elmengaard, B, Bechtold, J & Søballe, K 2005, ' In vivo effects of RGD-coated titanium implants inserted in two bone-gap models ', Journal of Biomedical Materials Research. Part A, vol. 75, no. 2, pp. 249-55 .
Elmengaard, B, Bechtold, J E & Søballe, K 2005, ' In vivo effects of RGD-coated titanium implants inserted in two bone-gap models ', Journal of Biomedical Materials Research. Part A, vol. 75, no. 2, pp. 249-55 . https://doi.org/10.1002/jbm.a.30301
Elmengaard, B, Bechtold, J E & Søballe, K 2005, ' In vivo effects of RGD-coated titanium implants inserted in two bone-gap models ', Journal of Biomedical Materials Research. Part A, vol. 75, no. 2, pp. 249-55 . https://doi.org/10.1002/jbm.a.30301
RGD (Arg-Gly-Asp) coating has been suggested to enhance implant fixation by facilitating the adhesion of osteogenic cells to implant surfaces. Orthopedic implants are unavoidably surrounded partly by gaps, and these regions represent a challenging en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba02ddc8dc9bd72be5114954818d25ec
https://pure.au.dk/portal/da/publications/in-vivo-effects-of-rgdcoated-titanium-implants-inserted-in-two-bonegap-models(59e49200-b4d0-11da-bee9-02004c4f4f50).html
https://pure.au.dk/portal/da/publications/in-vivo-effects-of-rgdcoated-titanium-implants-inserted-in-two-bonegap-models(59e49200-b4d0-11da-bee9-02004c4f4f50).html