Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Oligonucleotides/chemistry"'
Dual‐Input Regulation and Positional Control in Hybrid Oligonucleotide/Discotic Supramolecular Wires
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie-International Edition, 57(18), 4976-4980. Wiley
Angewandte Chemie International Edition
Angewandte Chemie-International Edition, 57(18), 4976-4980. Wiley
Angewandte Chemie International Edition
The combination of oligonucleotides and synthetic supramolecular systems allows for novel and long‐needed modes of regulation of the self‐assembly of both molecular elements. Discotic molecules were conjugated with short oligonucleotides and thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f58163c55f82814815c71afce0839c8
http://europepmc.org/articles/PMC5969285
http://europepmc.org/articles/PMC5969285
Autor:
Chenguang Lou, Knud J. Jensen, Niels Johan Christensen, Jesper Wengel, Kasper K. Sørensen, Maria Ejlersen
Publikováno v:
Ejlersen, M, Christensen, N J, Sørensen, K K, Jensen, K J, Wengel, J & Lou, C 2018, ' Synergy of Two Highly Specific Biomolecular Recognition Events : Aligning an AT-Hook Peptide in DNA Minor Grooves via Covalent Conjugation to 2'-Amino-LNA ', Bioconjugate Chemistry, vol. 29, no. 4, pp. 1025–1029 . https://doi.org/10.1021/acs.bioconjchem.8b00101
Two highly specific biomolecular recognition events, nucleic acid duplex hybridization and DNA-peptide recognition in the minor groove, were coalesced in a miniature ensemble for the first time by covalently attaching a natural AT-hook peptide motif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5abf1193ad810de17897f41cd5ff4db
https://findresearcher.sdu.dk:8443/ws/files/137708443/Synergy_of_two_highly_specific_biomolecular_recognition_events_aligning_an_AT_hook_peptide_in_DNA_minor_grooves_via_covalent_conjugation_to_2_amino_LNA.pdf
https://findresearcher.sdu.dk:8443/ws/files/137708443/Synergy_of_two_highly_specific_biomolecular_recognition_events_aligning_an_AT_hook_peptide_in_DNA_minor_grooves_via_covalent_conjugation_to_2_amino_LNA.pdf
Autor:
Pedro Moreno, Alexandra A.P. Mansur, Victoria Leiro, Joyce C. C. Santos, Ana Paula Pêgo, Herman S. Mansur
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cationic polymers have recently attracted attention due to their proven potential for nonviral gene delivery. In this study, we report novel biocompatible nanocomplexes produced using chemically functionalized N,N,N-trimethyl chitosan (TMC) with diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3196da9d4130e52d22218e9d3eeb9a
https://doi.org/10.1039/c5sm01403d
https://doi.org/10.1039/c5sm01403d
Autor:
Ulla Jakobsen, Stefan Vogel
Publikováno v:
Vogel, S & Jakobsen, U 2013, ' Assembly of Liposomes Controlled by Triple Helix Formation ', Bioconjugate Chemistry, vol. 24, no. 9, pp. 1485−1495 . https://doi.org/10.1021/bc300690m
Attachment of DNA to the surface of different solid nanoparticles (e.g., gold and silica nanoparticles) is well established, and a number of DNA-modified solid nanoparticle systems have been applied to thermal denaturation analysis of oligonucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9b6416e5c506e1270ed99268a29909
https://doi.org/10.1021/bc300690m
https://doi.org/10.1021/bc300690m
Autor:
Kathryn S. Torok, Christian Damsgaard Jørgensen, Simone V Samuelsen, Kira Astakhova, Elizabeth D. Mellins
Publikováno v:
PLoS ONE
Samuelsen, S, Jørgensen, C D, Mellins, E D, Torok, K S & Astakhova, K 2018, ' Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens ', PLOS ONE, vol. 13, no. 4, e0195381 . https://doi.org/10.1371/journal.pone.0195381
PLoS ONE, Vol 13, Iss 4, p e0195381 (2018)
Samuelsen, S, Jørgensen, C D, Mellins, E D, Torok, K S & Astakhova, K 2018, ' Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens ', P L o S One, vol. 13, no. 4, e0195381 . https://doi.org/10.1371/journal.pone.0195381
Samuelsen, S, Jørgensen, C D, Mellins, E D, Torok, K S & Astakhova, K 2018, ' Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens ', PLOS ONE, vol. 13, no. 4, e0195381 . https://doi.org/10.1371/journal.pone.0195381
PLoS ONE, Vol 13, Iss 4, p e0195381 (2018)
Samuelsen, S, Jørgensen, C D, Mellins, E D, Torok, K S & Astakhova, K 2018, ' Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens ', P L o S One, vol. 13, no. 4, e0195381 . https://doi.org/10.1371/journal.pone.0195381
In this study, we developed a series of synthetic oligonucleotides that allowed us to investigate the details on the antigen recognition by autoimmune antibodies in localized scleroderma subjects. Besides dramatically improved analytical specificity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c555e9c86b94c87652ae7e2be672fcf
https://doi.org/10.1371/journal.pone.0195381
https://doi.org/10.1371/journal.pone.0195381
Autor:
Paul de Hoog, Marguerite Pitié, Patrick Gamez, Giulio Amadei, Bernard Meunier, Robert Kiss, Jan Reedijk
Publikováno v:
Journal of Biological Inorganic Chemistry
Journal of Biological Inorganic Chemistry, 13(4), 575-586
JBIC. Journal of biological inorganic chemistry, 13 (4
Journal of Biological Inorganic Chemistry, 13(4), 575-586
JBIC. Journal of biological inorganic chemistry, 13 (4
The synthesis and nuclease activity of a new bifunctional heterodinuclear platinum-copper complex are reported. The design of this ditopic coordination compound is based on the specific mode of action of each component, namely, cisplatin and Cu(3-Cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6e6f93800f6980785467a1b3c1d64e
https://doi.org/10.1007/s00775-008-0346-y
https://doi.org/10.1007/s00775-008-0346-y
Autor:
Felipe Marques Souza de Oliveira, M Karoliina Hirvonen, Ola Söderberg, Johannes Haybaeck, Masood Kamali-Moghaddam, Linda Arngården, Liza Löf, Gaëlle Cane, Björn Koos, U. Helena Danielson, Manfred Auer, Carl-Magnus Clausson, Vladimir O. Talibov, Nhan T. Pham, Johan Heldin, Axel Klaesson, Karin Grannas
Publikováno v:
Nature Communications
Koos, B, Cane, G, Grannas, K, Löf, L, Arngården, L, Heldin, J, Clausson, C-M, Klaesson, A, Hirvonen, M K, de Oliveira, F M S, Talibov, V O, Pham, N T, Auer, M, Danielson, U H, Haybaeck, J, Kamali-Moghaddam, M & Söderberg, O 2015, ' Proximity-dependent initiation of hybridization chain reaction ', Nature Communications, vol. 6, 7294 . https://doi.org/10.1038/ncomms8294
Koos, B, Cane, G, Grannas, K, Löf, L, Arngården, L, Heldin, J, Clausson, C-M, Klaesson, A, Hirvonen, M K, de Oliveira, F M S, Talibov, V O, Pham, N T, Auer, M, Danielson, U H, Haybaeck, J, Kamali-Moghaddam, M & Söderberg, O 2015, ' Proximity-dependent initiation of hybridization chain reaction ', Nature Communications, vol. 6, 7294 . https://doi.org/10.1038/ncomms8294
Sensitive detection of protein interactions and post-translational modifications of native proteins is a challenge for research and diagnostic purposes. A method for this, which could be used in point-of-care devices and high-throughput screening, sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5068a93d969cd1b3f31cf7d0d8e9490
https://doi.org/10.1038/ncomms8294
https://doi.org/10.1038/ncomms8294
Autor:
Stacey L. Edwards, Michael B. Petersen, Kristine M. Hillman, Vasanthanathan Poongavanam, Maja Marušič, Janez Plavec, Rikke Leth-Larsen, Rakesh N. Veedu, Kislay Roy, Jesper Wengel, Jagat R. Kanwar, Neerati Prasad
Publikováno v:
Edwards, S L, Poongavanam, V, R Kanwar, J, Roy, K, M. Hillman, K, Prasad, N, Leth-Larsen, R, Petersen, M, Marusic, M, Plavec, J, Wengel, J & Veedu, R N 2015, ' Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition ', Chemical Communications, vol. 51, no. 46, pp. 9499-9502 . https://doi.org/10.1039/c5cc02756j
In this study, we investigated the efficacy of an LNA (locked nucleic acid)-modified DNA aptamer named RNV66 targeting VEGF against various breast cancer cell lines. Our results demonstrate that RNV66 efficiently inhibits breast cancer cell prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04fe8e33bcaade89338e5c0441d9769e
https://pubmed.ncbi.nlm.nih.gov/25968110
https://pubmed.ncbi.nlm.nih.gov/25968110
Autor:
Tom Ellenberger, Christine A. Shaw, Marco A. Azaro, Arthur Landy, Tapan K. Biswas, Marta Radman-Livaja
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2003, 11 (3), pp.783--94. ⟨10.1016/S1097-2765(03)00111-4⟩
Molecular Cell, Elsevier, 2003, 11 (3), pp.783--94. ⟨10.1016/S1097-2765(03)00111-4⟩
lambda integrase (Int) mediates recombination between attachment sites on lambda phage and E. coli DNAs. With the assistance of accessory proteins that induce DNA loops, Int bridges pairs of distinct arm- and core-type DNA binding sites to form synap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80c6360d56769e3757395be0f994244
https://doi.org/10.1016/s1097-2765(03)00111-4
https://doi.org/10.1016/s1097-2765(03)00111-4
Autor:
J. P. H. Burbach, J. G. Verbalis, F.W. van Leeuwen, R. A. N. Adan, M. A. F. Sonnemans, Madeleine R. Brouns, G. Hoffman
Publikováno v:
Endocrinology, 136(9), 4022-4028. The Endocrine Society
Adan, R A, Van Leeuwen, F W, Sonnemans, M A, Brouns, M, Hoffman, G, Verbalis, J G & Burbach, J P 1995, ' Rat oxytocin receptor in brain, pituitary, mammary gland, and uterus : partial sequence and immunocytochemical localization ', Endocrinology, vol. 136, no. 9, pp. 4022-4028 . https://doi.org/10.1210/endo.136.9.7649111
Adan, R A, Van Leeuwen, F W, Sonnemans, M A, Brouns, M, Hoffman, G, Verbalis, J G & Burbach, J P 1995, ' Rat oxytocin receptor in brain, pituitary, mammary gland, and uterus : partial sequence and immunocytochemical localization ', Endocrinology, vol. 136, no. 9, pp. 4022-4028 . https://doi.org/10.1210/endo.136.9.7649111
Partial complementary DNAs of an oxytocin (OT) receptor were cloned from rat brain and uterus. The complementary DNAs encoded for the same amino acid sequence, which showed a high degree of homology with the human and porcine uterine OT receptors, ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168dc470b332a5d8f0368427f919c9e9
https://doi.org/10.1210/endo.136.9.7649111
https://doi.org/10.1210/endo.136.9.7649111