Zobrazeno 1 - 10
of 1 442
pro vyhledávání: '"Oligomerization domain"'
Autor:
Yong He, Xin Wang, Li-Sheng Chen, Lei Chang, Ting-Ting He, Ao-Zhe Zhang, Hao-Tian Li, Shi-Zhang Wei, Man-Yi Jing, Yan-Ling Zhao
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 10, Iss 3, Pp 303-315 (2024)
Objective: Chronic atrophic gastritis (CAG) is a complex and burdensome disease. However, side effects and compliance issues cannot be ignored due to the long treatment cycle. Numerous studies have confirmed the effectiveness of rutaecarpine (RUT) fo
Externí odkaz:
https://doaj.org/article/511027d26c2a4b128d6419618594b86c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Loss-of-function mutations in nucleotide-binding oligomerization domain 2 (NOD2) constitute the primary risk factors for Crohn’s disease. NOD2 is an intracellular sensor for muramyl dipeptide (MDP), a small molecule derived from the peptidoglycan l
Externí odkaz:
https://doaj.org/article/9f173f2b96d5413bae2d4fdf8f772407
Autor:
Sijie Jiang, Benjian Zhang, Sihui Wen, Shenghao Cheng, Yingchun Shen, Shaobing Xie, Zhihai Xie, Weihong Jiang
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e38029- (2024)
Background: Previous investigations have provided limited insight into the role of oxidative stress in nasal mucosa inflammation. The aim of this study was to investigate the mechanism of oxidative stress in the epithelial cells of chronic rhinosinus
Externí odkaz:
https://doaj.org/article/44f3625787874413bf1aa0aa0b56fd8a
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivesYao syndrome (YAOS, OMIM# 617321) is a kind of systemic autoinflammatory diseases (SAIDs) linked to the nucleotide-binding oligomerization domain containing 2 (NOD2). Clinical reports of YAOS in China are sparse. Herein, we reported the lar
Externí odkaz:
https://doaj.org/article/83da31e90d394d3db7d3fecd38c5d824
Autor:
Jingwen Qiu, Jing Wu, Wenwen Chen, Yu Ruan, Jingning Mao, Shue Li, Xuan Tang, Lei Zhao, Shengbing Li, Ke Li, Dongfang Liu, Yaqian Duan
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) plays a pivotal role in inducing metabolic inflammation in diabetes. Additionally, the NOD1 ligand disrupts the equilibrium of bone marrow-derived hematopoietic
Externí odkaz:
https://doaj.org/article/792c70f65dec4f9380d206ed4037e35b
Autor:
Jingyuan Zhang, Yi Luo, Bingxuan Wu, Xin Huang, Mengzhu Zhao, Na Wu, Junke Miao, Ji Li, Lei Zhu, Di Wu, Min Shen
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Background and objectives The study investigated the pathogenesis of Yao syndrome (YAOS), a rare systemic autoinflammatory disease associated with the nucleotide-binding oligomerization domain containing 2 (NOD2) gene variants. Methods RNA s
Externí odkaz:
https://doaj.org/article/ed9935d638e1469ca9bde11edc71d39e
Autor:
Jiang, Sijie a, b, c, d, Zhang, Benjian a, b, c, d, Wen, Sihui a, b, c, d, Cheng, Shenghao a, b, c, d, Shen, Yingchun e, Xie, Shaobing a, b, c, d, ⁎⁎, Xie, Zhihai a, b, c, d, ⁎⁎⁎, Jiang, Weihong a, b, c, d, ⁎
Publikováno v:
In Heliyon 30 September 2024 10(18)
Publikováno v:
Biologics: Targets & Therapy, Vol Volume 17, Pp 167-180 (2023)
Xin Ma,* Junxia Jiao,* Mayila Aierken,* Hong Sun, Li Chen Department of Clinical Laboratory, Urumqi Friendship Hospital, Urumqi, Xinjiang Uygur Autonomous Region, People’s Republic of China*These authors contributed equally to this
Externí odkaz:
https://doaj.org/article/1774bb0dcff84563b5006b3cf8dcdd5c
Autor:
Tianshu WANG, Dan GAO, Dan ZHAO, Jiaping HUAN, Xiao HAN, Jing SONG, Linping WANG, Huifang ZHANG, Qiao NIU, Xiaoting LU
Publikováno v:
环境与职业医学, Vol 40, Iss 11, Pp 1250-1256 (2023)
BackgroundAluminum activates signal transducer and activator of transcription 3 (STAT3), causing microglial nucleotide-binding and oligomerization domain-like receptors protein 3 (NLRP3) inflammasome activation and inflammatory responses and producin
Externí odkaz:
https://doaj.org/article/a1d55940ea4e42fd860f7592f6823f28
Autor:
焦俊萍，鲍军强，史慧敏，高超，田书娟
Publikováno v:
Zhongguo cuzhong zazhi, Vol 18, Iss 9, Pp 1006-1013 (2023)
目的 探讨漆酶基因LACC1对脑梗死后缺血再灌注损伤的影响及其机制。 方法 ①采购C57BL/6J LACC1基因敲除（LACC1-/-）小鼠20只，野生型小鼠20只，建立大脑中动脉闭塞/再灌注（middle cerebral artery oc
Externí odkaz:
https://doaj.org/article/487ca9537ce445378e7627962a0fdf5b