Výsledky vyhledávání - "Oligodeoxyribonucleotides/chemistry"

Modification of oligodeoxynucleotides by on-column Suzuki cross-coupling reactions

Autor: Yogesh S. Sanghvi, Maria Ejlersen, Chenguang Lou, Yitzhak Tor, Jesper Wengel

Publikováno v: Ejlersen, M, Lou, C, Sanghvi, Y S, Tor, Y & Wengel, J 2018, ' Modification of oligodeoxynucleotides by on-column Suzuki cross-coupling reactions ', Chemical Communications, vol. 54, no. 57, pp. 8003-8006 . https://doi.org/10.1039/c8cc01360h

The on-column functionalization of oligodeoxynucleotides via base-free Suzuki cross-coupling reactions is reported herein. These cross-coupling reactions were carried out with various boronic acids and either full-length modified oligonucleotides con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd34cf39df5473c88ede221c3b95bc68
https://doi.org/10.1039/c8cc01360h

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The mammary factor MPBF is a prolactin-induced transcriptional regulator which binds to STAT factor recognition sites

Autor: Thomas G. Burdon, Christine J. Watson, A. John Clark, Jerome Demmer

Publikováno v: Burdon, T, Demmer, J, Clark, A J & Watson, C J 1994, ' The mammary factor MPBF is a prolactin-induced transcriptional regulator which binds to STAT factor recognition sites ', FEBS Letters, vol. 350, no. 2-3, pp. 177-82 .

Site-directed mutagenesis of the three binding sites for the mammary factor MPBF in the β-lactoglobulin (BLG) promoter demonstrates that MPBF is a transcriptional activator of the BLG gene in mammary cells. MPBF requires phosphorylation on tyrosine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a3e5eceb3331d9bff0b35aa157b971
https://doi.org/10.1016/0014-5793(94)00757-8

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Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network

Autor: Joseph Lin, Allan D. Shapiro, Suzanne R. Pfeffer, Markus A. Riederer, Thierry Soldati

Publikováno v: The Journal of Cell Biology
Scopus-Elsevier
The Journal of Cell Biology, Vol. 125, No 3 (1994) pp. 573-82

Newly synthesized lysosomal enzymes bind to mannose 6-phosphate receptors (MPRs) in the TGN, and are carried to prelysosomes, where they are released. MPRs then return to the TGN for another round of transport. Rab9 is a ras-like GTPase which facilit

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https://doi.org/10.1083/jcb.125.3.573

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Imporved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide

Autor: Bernard Lebleu, Anne-Marie Aubertin, J P Bongartz, P G Milhaud

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 1994, 22 (22), pp.4681--8. ⟨10.1093/nar/22.22.4681⟩

Recently several groups reported a dramatic improvement of reporter gene transfection efficiency using a fusogenic peptide, derived from the Influenza hemagglutinin envelop protein. This peptide changes conformation at acidic pH and destabilizes the

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https://doi.org/10.1093/nar/22.22.4681

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Superantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus

Autor: Hans Acha-Orbea, H R MacDonald, A N Shakhov, Shozo Izui, Leonardo Scarpellino, Werner Held, Gary A. Waanders

Publikováno v: Journal of Experimental Medicine, vol. 177, no. 2, pp. 359-366
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 177, No 2 (1993) pp. 359-366

Superantigens are defined by their ability to stimulate a large fraction of T cells via interaction with the T cell receptor (TCR) V beta domain. Endogenous superantigens, classically termed minor lymphocyte-stimulating (Mls) antigens, were recently

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https://doi.org/10.1084/jem.177.2.359

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Transient translational silencing by reversible mRNA deadenylation

Autor: Andrew L. Darrow, Jean-Dominique Vassalli, Sidney Strickland, Marcia L. O’Connell, Joaquin Huarte, Andre Stutz, Dominique Belin, Pascale Gubler

Publikováno v: Cell, Vol. 69, No 6 (1992) pp. 1021-1030

Tissue-type plasminogen activator (tPA) mRNA is stored, stable and untranslated, in the cytoplasm of fully grown primary mouse oocytes. Dormancy is associated with an unusually short poly(A) tail, and poly(A) tail elongation controls tPA mRNA transla

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https://doi.org/10.1016/0092-8674(92)90620-r

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Phosphorothioate-modified oligodeoxynucleotides inhibit human cytomegalovirus replication by blocking virus entry

Autor: Giorgio Gribaudo, Santo Landolfo, Patrizia Caposio, Anna Luganini

Publikováno v: Antimicrobial agents and chemotherapy. 52(3)

Studies in animal models have provided evidence that Toll-like receptor 9 (TLR9) agonists, such as synthetic oligodeoxynucleotides (ODNs) that contain immunostimulatory deoxycytidyl-deoxyguanosine (CpG) motifs (CpG ODNs), protect against a wide range

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https://pubmed.ncbi.nlm.nih.gov/18180342

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Kinetic study of azole-bridged dinuclear platinum(II) complexes reacting with a hairpin-stabilized double-stranded oligonucleotide

Autor: Jiří Kozelka, Sophie Bombard, Sandrine Perrier, Jan Reedijk, Seiji Komeda

Publikováno v: Journal of Inorganic Biochemistry
Journal of Inorganic Biochemistry, Elsevier, 2003, 96 (2-3), pp.357-366

The cytotoxic dinuclear platinum(II) complexes [[cis-Pt(NH(3))(2)](2)(mu-OH)(mu-pz)](NO(3))(2) (pz=pyrazolate) (1) and [[cis-Pt(NH(3))(2)](2)(mu-OH)(mu-1,2,3-ta-N1,N2)](NO(3))(2) (1,2,3-ta=1,2,3-triazolate) (2), were allowed to react with the hairpin

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https://hal.archives-ouvertes.fr/hal-00103695

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Isolation of Su(var)3-7 mutations by homologous recombination in Drosophila melanogaster

Autor: Pierre Spierer, Yannis Jaquet, Carole Seum, Anne Spierer, Marion Delattre, Daniel Pauli

Publikováno v: Genetics, Vol. 161, No 3 (2002) pp. 1125-36

The Su(var)3-7 gene, a haplo-suppressor and triplo-enhancer of position-effect variegation (PEV), encodes a zinc finger heterochromatin-associated protein. To understand the role of this protein in heterochromatin and genomic silencing, mutations wer

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https://archive-ouverte.unige.ch/unige:9883

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A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity

Autor: P. Emery, Walter Reith, Bernard Mach, Philipp Bucher, Michel Strubin, Kay Hofmann

Publikováno v: Molecular and Cellular Biology, Vol. 16, No 8 (1996) pp. 4486-4494

The RFX DNA binding domain is a novel motif that has been conserved in a growing number of dimeric DNA-binding proteins, having diverse regulatory functions, in eukaryotic organisms ranging from yeasts to humans. To characterize this novel motif, we

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https://archive-ouverte.unige.ch/unige:11234

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