Differential targeting of lysophosphatidic acid LPA 1 , LPA 2 , and LPA 3 receptor signalling by tricyclic and tetracyclic antidepressants.

Autor: Olianas MC; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences, University of Cagliari, 09042, Monserrato, (CA), Italy., Dedoni S; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences, University of Cagliari, 09042, Monserrato, (CA), Italy., Onali P; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences, University of Cagliari, 09042, Monserrato, (CA), Italy. Electronic address: onali@unica.it.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2023 Nov 15; Vol. 959, pp. 176064. Date of Electronic Publication: 2023 Sep 25.

The Neurotrophin Receptor TrkC as a Novel Molecular Target of the Antineuroblastoma Action of Valproic Acid.

Autor: Dedoni S; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, University of Cagliari, 09042 Monserrato, Italy., Marras L; Section of Microbiology, Department of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy., Olianas MC; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, University of Cagliari, 09042 Monserrato, Italy., Ingianni A; Section of Microbiology, Department of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy., Onali P; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, University of Cagliari, 09042 Monserrato, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Jul 21; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 21.

Valproic acid upregulates the expression of the p75NTR/sortilin receptor complex to induce neuronal apoptosis.

Autor: Dedoni S; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Monserrato, CA, Italy., Marras L; Section of Microbiology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Olianas MC; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Monserrato, CA, Italy., Ingianni A; Section of Microbiology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Onali P; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Monserrato, CA, Italy. onali@unica.it.

Publikováno v: Apoptosis : an international journal on programmed cell death [Apoptosis] 2020 Oct; Vol. 25 (9-10), pp. 697-714.

Downregulation of TrkB Expression and Signaling by Valproic Acid and Other Histone Deacetylase Inhibitors.

Autor: Dedoni S; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences (S.D., M.C.O., P.O.) and Section of Microbiology, Department of Biomedical Sciences (L.M., A.I.), University of Cagliari, Cagliari, Italy., Marras L; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences (S.D., M.C.O., P.O.) and Section of Microbiology, Department of Biomedical Sciences (L.M., A.I.), University of Cagliari, Cagliari, Italy., Olianas MC; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences (S.D., M.C.O., P.O.) and Section of Microbiology, Department of Biomedical Sciences (L.M., A.I.), University of Cagliari, Cagliari, Italy., Ingianni A; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences (S.D., M.C.O., P.O.) and Section of Microbiology, Department of Biomedical Sciences (L.M., A.I.), University of Cagliari, Cagliari, Italy., Onali P; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences (S.D., M.C.O., P.O.) and Section of Microbiology, Department of Biomedical Sciences (L.M., A.I.), University of Cagliari, Cagliari, Italy onali@unica.it.

Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2019 Sep; Vol. 370 (3), pp. 490-503. Date of Electronic Publication: 2019 Jul 15.

Muscarinic Acetylcholine Receptors Potentiate 5'-Adenosine Monophosphate-Activated Protein Kinase Stimulation and Glucose Uptake Triggered by Thapsigargin-Induced Store-Operated Ca ²⁺ Entry in Human Neuroblastoma Cells.

Autor: Olianas MC; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042, Monserrato, CA, Italy., Dedoni S; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042, Monserrato, CA, Italy., Onali P; Laboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042, Monserrato, CA, Italy. onali@unica.it.

Publikováno v: Neurochemical research [Neurochem Res] 2018 Feb; Vol. 43 (2), pp. 245-258. Date of Electronic Publication: 2017 Oct 09.