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Akademický článek

Lysophosphatidic Acid Stimulates Mitogenic Activity and Signaling in Human Neuroblastoma Cells through a Crosstalk with Anaplastic Lymphoma Kinase.

Autor: Dedoni, Simona¹ (AUTHOR) dedoni@unica.it, Olianas, Maria C.¹ (AUTHOR), Onali, Pierluigi¹ (AUTHOR) onali@unica.it

Publikováno v: Biomolecules (2218-273X). Jun2024, Vol. 14 Issue 6, p631. 21p.

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Akademický článek

Combined High—Throughput Proteomics and Random Forest Machine-Learning Approach Differentiates and Classifies Metabolic, Immune, Signaling and ECM Intra-Tumor Heterogeneity of Colorectal Cancer

Autor: Cristina Contini, Barbara Manconi, Alessandra Olianas, Giulia Guadalupi, Alessandra Schirru, Luigi Zorcolo, Massimo Castagnola, Irene Messana, Gavino Faa, Giacomo Diaz, Tiziana Cabras

Publikováno v: Cells, Vol 13, Iss 16, p 1311 (2024)

Colorectal cancer (CRC) is a frequent, worldwide tumor described for its huge complexity, including inter-/intra-heterogeneity and tumor microenvironment (TME) variability. Intra-tumor heterogeneity and its connections with metabolic reprogramming an

Externí odkaz: https://doaj.org/article/1d0e0d32178540e5b4c651ccb03c8f00

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Akademický článek

Purification and Characterization of Proteinaceous Thermostable α-Amylase Inhibitor from Sardinian Common Bean Nieddone Cultivar (Phaseolus vulgaris L.)

Autor: Stefania Peddio, Sonia Lorrai, Tinuccia Dettori, Cristina Contini, Alessandra Olianas, Barbara Manconi, Antonio Rescigno, Paolo Zucca

Publikováno v: Plants, Vol 13, Iss 15, p 2074 (2024)

The increasing need for new treatments for obesity and diabetes has led to the development of new drugs and food supplements that could reduce carbohydrate absorption. Many starch blockers, based on common bean proteinaceous inhibitors against α-amy

Externí odkaz: https://doaj.org/article/d3fa574fd5824035b237fe9b68e5398f

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Akademický článek

Thymosin β4 and β10 Expression in Human Organs during Development: A Review

Autor: Gavino Faa, Irene Messana, Pierpaolo Coni, Monica Piras, Giuseppina Pichiri, Marco Piludu, Federica Iavarone, Claudia Desiderio, Giovanni Vento, Chiara Tirone, Barbara Manconi, Alessandra Olianas, Cristina Contini, Tiziana Cabras, Massimo Castagnola

Publikováno v: Cells, Vol 13, Iss 13, p 1115 (2024)

This review summarizes the results of a series of studies performed by our group with the aim to define the expression levels of thymosin β4 and thymosin β10 over time, starting from fetal development to different ages after birth, in different hum

Externí odkaz: https://doaj.org/article/996e1d1c6da0452891fee95599973aa1

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Akademický článek

Lysophosphatidic Acid Stimulates Mitogenic Activity and Signaling in Human Neuroblastoma Cells through a Crosstalk with Anaplastic Lymphoma Kinase

Autor: Simona Dedoni, Maria C. Olianas, Pierluigi Onali

Publikováno v: Biomolecules, Vol 14, Iss 6, p 631 (2024)

Lysophosphatidic acid (LPA) is a well-documented pro-oncogenic factor in different cancers, but relatively little is known on its biological activity in neuroblastoma. The LPA effects and the participation of the tyrosine kinase receptor anaplastic l

Externí odkaz: https://doaj.org/article/7e5fbad13c84405a9274e03ba07b9c22

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