Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Olha Klyuchivska"'
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Akademický článek
Magnetic Temperature-Sensitive Solid-Lipid Particles for Targeting and Killing Tumor Cells
Autor: Małgorzata Świętek, Rostyslav Panchuk, Nadia Skorokhyd, Peter Černoch, Nataliya Finiuk, Olha Klyuchivska, Martin Hrubý, Matúš Molčan, Walter Berger, Jirí Trousil, Rostyslav Stoika, Daniel Horák
Publikováno v: Frontiers in Chemistry, Vol 8 (2020)
Magnetic and temperature-sensitive solid lipid particles (mag. SLPs) were prepared in the presence of oleic acid-coated iron oxide (IO-OA) nanoparticles with 1-tetradecanol and poly(ethylene oxide)-block-poly(ε-caprolactone) as lipid and stabilizing
Externí odkaz: https://doaj.org/article/2456ba3557684b35a7422bb6530f3d72
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2
Novel N-(4-thiocyanatophenyl)-1H-1,2,3-triazole-4-carboxamides exhibit selective cytotoxic activity at nanomolar doses towards human leukemic T-cells
Autor: Nazariy Pokhodylo, Nataliya Finiuk, Olha Klyuchivska, Mykola A. Тupychak, Vasyl Matiychuk, Evgeny Goreshnik, Rostyslav Stoika
Publikováno v: European journal of medicinal chemistry. 241
The N-(4-thiocyanatophenyl)-1H-1,2,3-triazole-4-carboxamides were synthesized via the condensation of variety of 1H-1,2,3-triazole-4-carboxylic acids and 4-thiocyanatoaniline using CDI as amide coupling reagents. According to computer-aided calculati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76154427633ba4cf15a990a9977c88a
https://pubmed.ncbi.nlm.nih.gov/35973342
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5
Primary discovery of 1-aryl-5-substituted-1H-1,2,3-triazole-4-carboxamides as promising antimicrobial agents
Autor: Olha Klyuchivska, Mykola D. Obushak, Rostyslav Stoika, Nazariy T. Pokhodylo, Vasyl S. Matiychuk, Nataliya Finiuk, Nazar Manko
Publikováno v: Journal of Molecular Structure. 1246:131146
Three series of novel 1H-1,2,3-triazole-4-carboxamides: 1-aryl-5-alkyl/aryl-1H-1,2,3-triazole-4-carboxamides, 1-aryl-5-amino-1H-1,2,3-triazole-4-carboxamides and 1,2,3-triazolo[1,5-a]quinazoline-3-carboxamides were synthesized via base-mediated click
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf4254b560a218eb303af11d1c5debe6
https://doi.org/10.1016/j.molstruc.2021.131146
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6
Proapoptotic effects of novel thiazole derivative on human glioma cells
Autor: Volodymyr Hreniukh, Andriy M. Babsky, Olha Klyuchivska, Rostyslav Stoika, Vasyl S. Matiychuk, R. R. Panchuk, I. I. Ivasechko, Yaryna Shalai, Mykola D. Obushak, Y. V. Ostapiuk, N. S. Finiuk
Publikováno v: Anti-cancer drugs. 30(1)
The aim of the present study was to investigate the antiproliferative and proapoptotic actions of N-(5-benzyl-1,3-thiazol-2-yl)-3,5-dimethyl-1-benzofuran-2-carboxamide derivative (compound 5) in glioma cells in comparison with the actions of temozolo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ed69e10c51bed5d022ecbb4ddf7ee6
https://pubmed.ncbi.nlm.nih.gov/30130258
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7
Enhanced cytotoxicity of anticancer drug delivered by novel nanoscale polymeric carrier
Autor: A Ryabceva, Senkiv Y, Yu. Ya. Kit, N. S. Finiuk, Natalya Mitina, Alexander Zaichenko, Olha Klyuchivska, Rostyslav Stoika, Shlyakhtina Y, Rostyslav Bilyy, Yevhen Filyak, Nataliya Boiko, N Skorohyd, R. R. Panchuk
Publikováno v: Journal of Physics: Conference Series. 429:012038
We compared in vitro action of highly toxic anticancer drug doxorubicin under its delivery to the mammalian tumor cells in free form and after encapsulation in novel bio-functionalized nanoscale polymeric carrier. Such encapsulation was found to enha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e999c65adcac95f3b19a8da3e8563f36
https://doi.org/10.1088/1742-6596/429/1/012038
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