Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Olga Zegarra-Moran"'
Autor:
Génesis Vega, Anita Guequén, Amber R. Philp, Ambra Gianotti, Llilian Arzola, Manuel Villalón, Olga Zegarra-Moran, Luis J.V. Galietta, Marcus A. Mall, Carlos A. Flores
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
Airway mucociliary clearance (MCC) is the main mechanism of lung defense keeping airways free of infection and mucus obstruction. Airway surface liquid volume, ciliary beating, and mucus are central for proper MCC and critically regulated by sodium a
Externí odkaz:
https://doaj.org/article/2f2d753697e0401fbc6275362b8638fb
Autor:
Elsa Hernando, Valeria Capurro, Claudia Cossu, Michele Fiore, María García-Valverde, Vanessa Soto-Cerrato, Ricardo Pérez-Tomás, Oscar Moran, Olga Zegarra-Moran, Roberto Quesada
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Anion selective ionophores, anionophores, are small molecules capable of facilitating the transmembrane transport of anions. Inspired in the structure of natural product prodigiosin, four novel anionophores 1a-d, including a 1,2,3-triazole g
Externí odkaz:
https://doaj.org/article/fc47a172d0f34f89a359a289471393b9
Publikováno v:
AIMS Molecular Science, Vol 1, Iss 4, Pp 141-161 (2014)
The cystic fibrosis transmembrane conductance regulator protein (CFTR) is a chloride channel highly expressed in the gills of Salmo salar, with a role in osmoregulation. It shares 60% identity with the human CFTR channel, mutations to which can cause
Externí odkaz:
https://doaj.org/article/44ae11f3c8c040fdae28099ca76a2f94
Autor:
Anita Guequén, Ambra Gianotti, Llilian Arzola, Manuel Villalón, Carlos A. Flores, Marcus A. Mall, Luis J. V. Galietta, Amber R. Philp, Génesis Vega, Olga Zegarra-Moran
Publikováno v:
JCI Insight
JCI Insight, Vol 5, Iss 16 (2020)
JCI Insight, Vol 5, Iss 16 (2020)
Airway mucociliary clearance (MCC) is the main mechanism of lung defense keeping airways free of infection and mucus obstruction. Airway surface liquid volume, ciliary beating, and mucus are central for proper MCC and critically regulated by sodium a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef48a9057a77f5c7c6ddff7b61fe9989
http://hdl.handle.net/11588/818326
http://hdl.handle.net/11588/818326
Autor:
Andrea Dardis, David Neil Cooper, Mirella Filocamo, Fabio Corsolini, Giulia Amico, Giovanni Candiano, Maurizio Bruschi, Genny Del Zotto, Nicoletta Pedemonte, Olga Zegarra-Moran, Susanna Lualdi, Valeria Tomati
Publikováno v:
Human Mutation. 38:849-862
The transfer of genomic information into the primary RNA sequence can be altered by RNA editing. We have previously shown that genomic variants can be RNA-edited to wild-type. The presence of distinct “edited” iduronate 2-sulfatase (IDS) mRNA tra
Publikováno v:
Cellular and Molecular Life Sciences. 74:117-128
CFTR protein is an ion channel regulated by cAMP-dependent phosphorylation and expressed in many types of epithelial cells. CFTR-mediated chloride and bicarbonate secretion play an important role in the respiratory and gastrointestinal systems. Pharm
Autor:
Emanuela Caci, Ambra Gianotti, Loretta Ferrera, Amber R. Philp, Carlos A. Flores, Olga Zegarra-Moran, Luis J. V. Galietta
Publikováno v:
European Journal of Pharmacology. 781:100-108
Defective epithelial chloride secretion occurs in humans with cystic fibrosis (CF), a genetic defect due to loss of function of CFTR, a cAMP-activated chloride channel. In the airways, absence of an active CFTR causes a severe lung disease. In mice,
Autor:
Roberto Quesada, Vanessa Soto-Cerrato, María García-Valverde, Oscar Moran, Valeria Capurro, Claudia Cossu, Olga Zegarra-Moran, Elsa Hernando, Michele Fiore, Ricardo Pérez-Tomás
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
Recercat. Dipósit de la Recerca de Catalunya
Scientific reports (Nature Publishing Group) 8 (2018). doi:10.1038/s41598-018-20708-3
info:cnr-pdr/source/autori:Hernando E, Capurro V, Cossu C, Fiore M, García-Valverde M, Soto-Cerrato V, Pérez-Tomás R, Moran O, Zegarra-Moran O, Quesada R/titolo:Small molecule anionophores promote transmembrane anion permeation matching CFTR activity/doi:10.1038%2Fs41598-018-20708-3/rivista:Scientific reports (Nature Publishing Group)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
Recercat. Dipósit de la Recerca de Catalunya
Scientific reports (Nature Publishing Group) 8 (2018). doi:10.1038/s41598-018-20708-3
info:cnr-pdr/source/autori:Hernando E, Capurro V, Cossu C, Fiore M, García-Valverde M, Soto-Cerrato V, Pérez-Tomás R, Moran O, Zegarra-Moran O, Quesada R/titolo:Small molecule anionophores promote transmembrane anion permeation matching CFTR activity/doi:10.1038%2Fs41598-018-20708-3/rivista:Scientific reports (Nature Publishing Group)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Dipòsit Digital de la UB
Universidad de Barcelona
Anion selective ionophores, anionophores, are small molecules capable of facilitating the transmembrane transport of anions. Inspired in the structure of natural product prodigiosin, four novel anionophores 1a-d, including a 1,2,3-triazole group, wer
Publikováno v:
AIMS Molecular Science, Vol 1, Iss 4, Pp 141-161 (2014)
The cystic fibrosis transmembrane conductance regulator protein (CFTR) is a chloride channel highly expressed in the gills of Salmo salar , with a role in osmoregulation. It shares 60% identity with the human CFTR channel, mutations to which can caus
Publikováno v:
Cellular and molecular life sciences (Print. ed.) 72 (2015): 1363–1375. doi:10.1007/s00018-014-1747-4
info:cnr-pdr/source/autori:Baroni, Debora; Zegarra-Moran, Olga; Moran, Oscar/titolo:Functional and pharmacological induced structural changes of the cystic fibrosis transmembrane conductance regulator in the membrane solved using SAXS/doi:10.1007%2Fs00018-014-1747-4/rivista:Cellular and molecular life sciences (Print. ed.)/anno:2015/pagina_da:1363/pagina_a:1375/intervallo_pagine:1363–1375/volume:72
info:cnr-pdr/source/autori:Baroni, Debora; Zegarra-Moran, Olga; Moran, Oscar/titolo:Functional and pharmacological induced structural changes of the cystic fibrosis transmembrane conductance regulator in the membrane solved using SAXS/doi:10.1007%2Fs00018-014-1747-4/rivista:Cellular and molecular life sciences (Print. ed.)/anno:2015/pagina_da:1363/pagina_a:1375/intervallo_pagine:1363–1375/volume:72
The cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is a membrane-integral protein that belongs to the ATP-binding cassette superfamily. Mutations in the CFTR gene cause cystic fibrosis in which salt, water, and protein tr