Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Olga Y Vekovischeva"'
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100188 (2014)
Abnormal excitatory glutamate neurotransmission and plasticity have been implicated in schizophrenia and affective disorders. Gria1-/- mice lacking GluA1 subunit (encoded by Gria1 gene) of AMPA-type glutamate receptor show robust novelty-induced hype
Externí odkaz:
https://doaj.org/article/8bbbce973a994f088f4ae5ff86f5ec67
Autor:
Elli Leppä, Anni-Maija Linden, Olga Y Vekovischeva, Jerome D Swinny, Ville Rantanen, Esko Toppila, Harald Höger, Werner Sieghart, Peer Wulff, William Wisden, Esa R Korpi
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24159 (2011)
We investigated the behavioral significance of fast synaptic inhibition by αβγ2-type GABA(A) receptors on parvalbumin (Pv) cells. The GABA(A) receptor γ2 subunit gene was selectively inactivated in Pv-positive neurons by Cre/loxP recombination. T
Externí odkaz:
https://doaj.org/article/8f70cbd9fc3c41b1a21aa27753246945
Publikováno v:
Neurochemical Research. 28:757-764
Development of tolerance to motor-impairing effects of repeated administration of moderate diazepam doses (5.0–7.5 mg/kg; three times daily PO 3 weeks) was compared between mice deficient in the cerebellar granule cell–restricted GABAA receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdd5b5899484273c94eeaefeb8b19d9b
https://doi.org/10.1023/a:1022870002722
https://doi.org/10.1023/a:1022870002722
Autor:
Mikko Uusi-Oukari, Peter H. Seeburg, Olga Y. Vekovischeva, Aapo Honkanen, Daniel Zamanillo, Oxana Echenko, Esa R. Korpi, Timo Seppälä, Rolf Sprengel
Publikováno v:
The Journal of Neuroscience
AMPA-type glutamate receptors have been suggested to be involved in the neurobiological mechanisms of drug addiction. We have made use of two mouse lines, which both have modulated AMPA receptor responses. The first line is entirely deficient in glut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6612120151d9e45a4ab91d0c8f7f8b
https://doi.org/10.1523/jneurosci.21-12-04451.2001
https://doi.org/10.1523/jneurosci.21-12-04451.2001
Autor:
Jari Heikkilä, Aapo Honkanen, Olga Y. Vekovischeva, Riitta Näkki, Maija Sarviharju, Antti Haapalinna, Esa R. Korpi
Publikováno v:
Pharmacology Biochemistry and Behavior. 67:793-799
The ability of the antagonists for the N-methyl-D-aspartate (NMDA) type of glutamate receptor to modulate locomotor activity were compared in alcohol-sensitive (or alcohol-nontolerant, ANT) and alcohol-insensitive (or alcohol-tolerant, AT) rat lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a44149140292c1b328027ae7cf40271
https://doi.org/10.1016/s0091-3057(00)00424-x
https://doi.org/10.1016/s0091-3057(00)00424-x
Publikováno v:
Addiction Biology. 5:463-467
Chronic alcohol administration increases the expression of cerebellum-specific GABA A receptor α6 subunit mRNA, protein and selective autoradiographical fingerprint on rat and mouse brain sections. We have tested whether the α6 gene is activated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31b8b838d4a88d5d0e9e00852fab3da
https://doi.org/10.1111/j.1369-1600.2000.tb00216.x
https://doi.org/10.1111/j.1369-1600.2000.tb00216.x
Publikováno v:
Brain Research. 837:184-187
Alcohol-sensitive ANT rats have a point mutation in the cerebellum-enriched GABA(A) receptor alpha6 subunit, which makes this subunit and the ANT rats in vivo highly sensitive to benzodiazepine agonists. In the elevated plus maze test of anxiety, dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf56bc3500e2784bb8ba4a012210172
https://doi.org/10.1016/s0006-8993(99)01691-1
https://doi.org/10.1016/s0006-8993(99)01691-1
Autor:
Riikka Mäkelä, Esa R. Korpi, Paula Koikkalainen, Raymonde Kleinz, William Wisden, Mikko Uusi-Oukari, Olga Y. Vekovischeva
Publikováno v:
European Journal of Neuroscience. 11:233-240
Benzodiazepine- and alcohol-induced ataxias in rodents have been proposed to be affected by the gamma-aminobutyric acid type A (GABAA) receptor alpha 6 subunit, which contributes to receptors specifically expressed in cerebellar granule cells. We hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1339b51d3acf348c886322035ecd9a23
https://doi.org/10.1046/j.1460-9568.1999.00421.x
https://doi.org/10.1046/j.1460-9568.1999.00421.x
Autor:
Teemu Aitta-aho, Pia Bäckström, Tommi Möykkynen, Olga Y. Vekovischeva, Anne Panhelainen, Esa R. Korpi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e38325 (2012)
PLoS ONE, Vol 7, Iss 5, p e38325 (2012)
In state-dependency, information retrieval is most efficient when the animal is in the same state as it was during the information acquisition. State-dependency has been implicated in a variety of learning and memory processes, but its mechanisms rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2562bfed3f01629ead8edd2ca13616f
http://europepmc.org/articles/PMC3365010
http://europepmc.org/articles/PMC3365010
Autor:
Nancy A. Ator, Anne Panhelainen, Teemu Aitta-aho, Elena Vashchinkina, Bjarke Ebert, Esa R. Korpi, Olga Y. Vekovischeva
Dopamine neurons of the ventral tegmental area (VTA) are involved at early phases of drug addiction. Even the firstin vivodose of various abused drugs induces glutamate receptor plasticity at the excitatory synapses of these neurons. Benzodiazepines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de8ddd29bffb8d46aaf8d7f88b700e8
https://europepmc.org/articles/PMC6622081/
https://europepmc.org/articles/PMC6622081/
