Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Olga V. Viktorovskaya"'
Autor:
Olga V. Viktorovskaya, Krysta L. Engel, Sarah L. French, Ping Cui, Paul J. Vandeventer, Emily M. Pavlovic, Ann L. Beyer, Craig D. Kaplan, David A. Schneider
Publikováno v:
Cell Reports, Vol 4, Iss 5, Pp 974-984 (2013)
Multisubunit RNA polymerases (msRNAPs) exhibit high sequence and structural homology, especially within their active sites, which is generally thought to result in msRNAP functional conservation. However, we show that mutations in the trigger loop (T
Externí odkaz:
https://doaj.org/article/f0f99011ac9e4e3baf5988e3f7050181
Autor:
Abigail K. Huffines, Krysta L. Engel, Sarah L. French, Yinfeng Zhang, Olga V. Viktorovskaya, David A. Schneider
Publikováno v:
The Journal of biological chemistry. 298(12)
One of the first steps in ribosome biogenesis is transcription of the ribosomal DNA by RNA polymerase I (Pol I). Processing of the resultant rRNA begins cotranscriptionally, and perturbation of Pol I transcription elongation results in defective rRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99b1a9112fcfcbb007b9fa3f4fd40c1
https://pubmed.ncbi.nlm.nih.gov/36423683
https://pubmed.ncbi.nlm.nih.gov/36423683
Autor:
James Chuang, Magdalena Murawska, Dan Spatt, Dhawal Jain, Olga V. Viktorovskaya, Fred Winston, L. Stirling Churchman, Francheska Lopez-Rivera, Peter J. Park, Natalia I. Reim
Publikováno v:
Genes Dev
Histone chaperones are critical for controlling chromatin integrity during transcription, DNA replication, and DNA repair. Three conserved and essential chaperones, Spt6, Spn1/Iws1, and FACT, associate with elongating RNA polymerase II and interact w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b4985214f38c9be8dc4206396d746b
https://doi.org/10.1101/gad.348431.121
https://doi.org/10.1101/gad.348431.121
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004921 (2016)
BackgroundThere are currently no vaccines or antivirals available for dengue virus infection, which can cause dengue hemorrhagic fever and death. A better understanding of the host pathogen interaction is required to develop effective therapies to tr
Externí odkaz:
https://doaj.org/article/ce256852b75a4ee688664c42f52b0546
Autor:
Dan Spatt, Magdalena Murawska, James Chuang, Peter J. Park, Natalia I. Reim, Fred Winston, Dhawal Jain, L. Stirling Churchman, Francheska Lopez-Rivera, Olga V. Viktorovskaya
SUMMARYHistone chaperones are critical for controlling chromatin integrity during transcription, DNA replication, and DNA repair. We have discovered that the physical interaction between two essential histone chaperones, Spt6 and Spn1/Iws1, is requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92bcbfb6d03df35cc647a3dc6164a989
https://doi.org/10.1101/2020.11.04.368589
https://doi.org/10.1101/2020.11.04.368589
Autor:
Elina Bychkova, Maria Sotskaya, Larisa V Barabanova, Zhanna Eliseeva, Anton Markov, Elizaveta Filippova, Olga V. Viktorovskaya
Publikováno v:
Gene. 769
Acromelanism is a temperature-dependent hypopigmentation pattern commonly manifested as the Himalayan coat color found in rabbits, rats, mice, minks, and gerbils, wherein the extreme “points” are dark and the torso is pale. It is known as the Sia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068a428ad50f259526e1e7af29dade79
https://pubmed.ncbi.nlm.nih.gov/33039541
https://pubmed.ncbi.nlm.nih.gov/33039541
Autor:
Magdalena Murawska, James Chuang, Fred Winston, Dan Spatt, L. Stirling Churchman, Olga V. Viktorovskaya, Stephen M. Doris
SUMMARYSpt6 is a conserved factor that controls transcription and chromatin structure across the genome. Although Spt6 is viewed as an elongation factor,spt6mutations inSaccharomyces cerevisiaeallow elevated levels of transcripts from within coding r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6420330ca08e2ae96c8e378d4fae4c3c
Publikováno v:
Molecular and Cellular Biology. 35:2321-2331
Spt6 (suppressor of Ty6) has many roles in transcription initiation and elongation by RNA polymerase (Pol) II. These effects are mediated through interactions with histones, transcription factors, and the RNA polymerase. Two lines of evidence suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3cfb0450de2732010fb857ac315cd6
https://doi.org/10.1128/mcb.01499-14
https://doi.org/10.1128/mcb.01499-14
Publikováno v:
Gene. 556:19-26
Eukaryotic cells express at least three unique nuclear RNA polymerases. The selective advantage provided by this enhanced complexity is a topic of fundamental interest in cell biology. It has long been known that the gene targets and transcription in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d041c49dcde7ce2cfab138d184d63f
https://doi.org/10.1016/j.gene.2014.10.035
https://doi.org/10.1016/j.gene.2014.10.035
Publikováno v:
PLOS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004921 (2016)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004921 (2016)
PLoS Neglected Tropical Diseases
Background There are currently no vaccines or antivirals available for dengue virus infection, which can cause dengue hemorrhagic fever and death. A better understanding of the host pathogen interaction is required to develop effective therapies to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26faaec3e3065c40da5b658518496c2