Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Olga V. Saik"'
Apoptosis Genes as a Key to Identification of Inverse Comorbidity of Huntington’s Disease and Cancer
Autor:
Elena Yu. Bragina, Densema E. Gomboeva, Olga V. Saik, Vladimir A. Ivanisenko, Maxim B. Freidin, Maria S. Nazarenko, Valery P. Puzyrev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9385 (2023)
Cancer and neurodegenerative disorders present overwhelming challenges for healthcare worldwide. Epidemiological studies showed a decrease in cancer rates in patients with neurodegenerative disorders, including the Huntington disease (HD). Apoptosis
Externí odkaz:
https://doaj.org/article/d8e959d39ece4e4a95d91549b7fbcd6c
Autor:
Timofey V. Ivanisenko, Olga V. Saik, Pavel S. Demenkov, Nikita V. Ivanisenko, Alexander N. Savostianov, Vladimir A. Ivanisenko
Publikováno v:
BMC Bioinformatics, Vol 21, Iss S11, Pp 1-21 (2020)
Abstract Background The rapid growth of scientific literature has rendered the task of finding relevant information one of the critical problems in almost any research. Search engines, like Google Scholar, Web of Knowledge, PubMed, Scopus, and others
Externí odkaz:
https://doaj.org/article/8259866ef97a4cadbffab867b381eca6
Autor:
Olga V. Saik, Vadim V. Nimaev, Dilovarkhuja B. Usmonov, Pavel S. Demenkov, Timofey V. Ivanisenko, Inna N. Lavrik, Vladimir A. Ivanisenko
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S2, Pp 117-131 (2019)
Abstract Background Currently, more than 150 million people worldwide suffer from lymphedema. It is a chronic progressive disease characterized by high-protein edema of various parts of the body due to defects in lymphatic drainage. Molecular-genetic
Externí odkaz:
https://doaj.org/article/2f68d18dcb734080988f06d31f119c38
Autor:
Vladimir A. Ivanisenko, Pavel S. Demenkov, Timofey V. Ivanisenko, Elena L. Mishchenko, Olga V. Saik
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S1, Pp 5-15 (2019)
Abstract Background Consideration of tissue-specific gene expression in reconstruction and analysis of molecular genetic networks is necessary for a proper description of the processes occurring in a specified tissue. Currently, there are a number of
Externí odkaz:
https://doaj.org/article/763d8bbe8ddc479ca9d19fd2801127c4
Autor:
Olga V. Saik, Vadim V. Klimontov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7247 (2022)
People with diabetes are more likely to have severe COVID-19 compared to the general population. Moreover, diabetes and COVID-19 demonstrate a certain parallelism in the mechanisms and organ damage. In this work, we applied bioinformatics analysis of
Externí odkaz:
https://doaj.org/article/57c94f1d32e647b1ac9e20c3c4a08ea1
Autor:
Olga V. Saik, Pavel S. Demenkov, Timofey V. Ivanisenko, Elena Yu Bragina, Maxim B. Freidin, Irina A. Goncharova, Victor E. Dosenko, Olga I. Zolotareva, Ralf Hofestaedt, Inna N. Lavrik, Evgeny I. Rogaev, Vladimir A. Ivanisenko
Publikováno v:
BMC Medical Genomics, Vol 11, Iss S1, Pp 61-76 (2018)
Abstract Background Hypertension and bronchial asthma are a major issue for people’s health. As of 2014, approximately one billion adults, or ~ 22% of the world population, have had hypertension. As of 2011, 235–330 million people globally have b
Externí odkaz:
https://doaj.org/article/0c88c88771ca4665bcf1b8bbe328a7c6
Autor:
Olga V. Saik, Vadim V. Klimontov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12419 (2021)
Hypoglycemia has been recognized as a risk factor for diabetic vascular complications and cognitive decline, but the molecular mechanisms of the effect of hypoglycemia on target organs are not fully understood. In this work, gene networks of hypoglyc
Externí odkaz:
https://doaj.org/article/64603f7b59d5443194d2959e45f540e5
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7783 (2021)
A growing body of evidence points to the role of glucose variability (GV) in the development of the microvascular and macrovascular complications of diabetes. In this review, we summarize data on GV-induced biochemical, cellular and molecular events
Externí odkaz:
https://doaj.org/article/0c93f95935644a85bb6bef770c5d37a1
Autor:
Vladimir V. Sherstyuk, Sergey P. Medvedev, Evgeniy A. Elisaphenko, Evgeniya A. Vaskova, Maxim T. Ri, Yuri V. Vyatkin, Olga V. Saik, Dmitry N. Shtokalo, Evgeniy A. Pokushalov, Suren M. Zakian
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract MicroRNAs (miRNAs) constitute a class of small noncoding RNAs that plays an important role in the post-transcriptional regulation of gene expression. Much evidence has demonstrated that miRNAs are involved in regulating the human and mouse p
Externí odkaz:
https://doaj.org/article/4290a1fa61c244d4b5bfea8034b6f997
Autor:
Olga V. Saik, Vadim V. Klimontov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8691 (2020)
Glucose variability (GV) has been recognized recently as a promoter of complications and therapeutic targets in diabetes. The aim of this study was to reconstruct and analyze gene networks related to GV in diabetes and its complications. For network
Externí odkaz:
https://doaj.org/article/e627c26859ca40c4a94b6ddcad8c305d