Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Olga V Volpert"'
Autor:
Dalia Martinez-Marin, Courtney Jarvis, Thomas Nelius, Werner de Riese, Olga V Volpert, Stéphanie Filleur
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174968 (2017)
Although inflammation and prostate cancer (PCa) have been linked, the molecular interactions between macrophages and PCa cells are poorly explored. Pigment Epithelium-Derived Factor (PEDF) is an anti-angiogenic and anti-tumor factor. We previously sh
Externí odkaz:
https://doaj.org/article/68f998169d2d488faf4e6bb5cb53cfd3
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 7, Pp 633-642 (2011)
Metastatic melanoma cells are highly adaptable to their in vivo microenvironment and can switch between protease-dependent mesenchymal and protease-independent amoeboid invasion to facilitate metastasis. Such adaptability can be visualized in vitro,
Externí odkaz:
https://doaj.org/article/abf7f92ebf7e42d78a2ec2b5395c9fe7
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83991 (2013)
miRNA regulate gene expression at post-transcriptional level and fine-tune the key biological processes, including cancer progression. Here, we demonstrate the involvement of miR-200 b in the metastatic spread of prostate cancer. We identified miR-20
Externí odkaz:
https://doaj.org/article/ac40a7c17f6049a19e0d064ad7940afe
Autor:
Yelena Mirochnik, Dorina Veliceasa, Latanya Williams, Kelly Maxwell, Alexander Yemelyanov, Irina Budunova, Olga V Volpert
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31052 (2012)
The accepted androgen receptor (AR) role is to promote proliferation and survival of prostate epithelium and thus prostate cancer progression. While growth-inhibitory, tumor-suppressive AR effects have also been documented, the underlying mechanisms
Externí odkaz:
https://doaj.org/article/0e4c38a515374fc1a7f4176f534426e1
Autor:
Amanda R. Haltom, Wafa E. Hassen, Janine Hensel, Jiha Kim, Hikaru Sugimoto, Bingrui Li, Kathleen M. McAndrews, Meagan R. Conner, Michelle L. Kirtley, Xin Luo, Bingqing Xie, Olga V. Volpert, Susan Olalekan, Natalia Maltsev, Anindita Basu, Valerie S. LeBleu, Raghu Kalluri
Publikováno v:
Extracellular Vesicle, Vol 1, Iss , Pp 100014- (2022)
Dysregulated Myc signaling is a key oncogenic pathway in glioblastoma multiforme (GBM). Yet, effective therapeutic targeting of Myc continues to be challenging. Here, we demonstrate that exosomes generated from human bone marrow mesenchymal stem cell
Externí odkaz:
https://doaj.org/article/31ae9f76978c40408bc4b64bc343197a
Autor:
Xunian Zhou, Paul Kurywchak, Kerri Wolf-Dennen, Sara P.Y. Che, Dinanath Sulakhe, Mark D’Souza, Bingqing Xie, Natalia Maltsev, T. Conrad Gilliam, Chia-Chin Wu, Kathleen M. McAndrews, Valerie S. LeBleu, David J. McConkey, Olga V. Volpert, Shanna M. Pretzsch, Bogdan A. Czerniak, Colin P. Dinney, Raghu Kalluri
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 360-376 (2021)
Bladder cancer (BC), a heterogeneous disease characterized by high recurrence rates, is diagnosed and monitored by cystoscopy. Accurate clinical staging based on biopsy remains a challenge, and additional, objective diagnostic tools are needed urgent
Externí odkaz:
https://doaj.org/article/bdca943877004a2b91e176430decece2
Autor:
Michael P. Plebanek, Nicholas L. Angeloni, Elena Vinokour, Jia Li, Anna Henkin, Dalia Martinez-Marin, Stephanie Filleur, Reshma Bhowmick, Jack Henkin, Stephen D. Miller, Igal Ifergan, Yesung Lee, Iman Osman, C. Shad Thaxton, Olga V. Volpert
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Exosomes are extracellular vesicles that can favor tumor development and metastasis. Here, the authors show that cancer exosomes may also exert a suppressive function; in fact, exosomes from non-metastatic melanoma cells can lead to the recruitment o
Externí odkaz:
https://doaj.org/article/0a21f57d94e44252ad7ff8007fe02002
Autor:
Olga V. Volpert, Andrew P. Mazar, Andrey Ugolkov, Oleksii Dubrovskyi, Elena Vinokour, Benilde Jimenez, Maria L. Deguiz, Nkechiyere G. Nwani
Supplemental Figure 1. Verification of PEDF knockdown Supplemental Figure 2. Verification of PEDF silencing in fibroblasts Supplemental Figure 3. The effect of PEDF expression in fibroblasts on tumor growth Supplemental Figure 4. The effect of endoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1f376f8587641c7c6028f2125e2958
https://doi.org/10.1158/0008-5472.22411488
https://doi.org/10.1158/0008-5472.22411488
Autor:
Olga V. Volpert, Andrew P. Mazar, Andrey Ugolkov, Oleksii Dubrovskyi, Elena Vinokour, Benilde Jimenez, Maria L. Deguiz, Nkechiyere G. Nwani
Loss of pigment epithelium-derived factor (PEDF, SERPINF1) in cancer cells is associated with poor prognosis and metastasis, but the contribution of stromal PEDF to cancer evolution is poorly understood. Therefore, we investigated the role of fibrobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4e15eefa9bff335b82e8682f1c611e9
https://doi.org/10.1158/0008-5472.c.6508233.v1
https://doi.org/10.1158/0008-5472.c.6508233.v1
Autor:
Olga V. Volpert, Andrew P. Mazar, Andrey Ugolkov, Oleksii Dubrovskyi, Elena Vinokour, Benilde Jimenez, Maria L. Deguiz, Nkechiyere G. Nwani
Legends for supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afef11961714b78b6abd0f41c3eef27
https://doi.org/10.1158/0008-5472.22411491
https://doi.org/10.1158/0008-5472.22411491