Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Olga V, Bocharova"'
Autor:
Vladimir D. Krasnobaev, Yaroslav V. Bershatsky, Olga V. Bocharova, Eduard V. Bocharov, Oleg V. Batishchev
Publikováno v:
Membranes, Vol 13, Iss 8, p 706 (2023)
One of the hallmarks of Alzheimer’s disease (AD) is the accumulation of amyloid beta (Aβ) peptides in the brain. The processing of amyloid precursor protein (APP) into Aβ is dependent on the location of APP in the membrane, membrane lipid composi
Externí odkaz:
https://doaj.org/article/b25979ecf2ab4069820d3e25ad924d01
Autor:
Petro Khoroshyy, Katalin Tenger, Rita V. Chertkova, Olga V. Bocharova, Mikhail P. Kirpichnikov, Natalia Borovok, Géza I. Groma, Dmitry A. Dolgikh, Alexander B. Kotlyar, László Zimányi
Publikováno v:
Molecules, Vol 26, Iss 22, p 6976 (2021)
Electron transfer within and between proteins is a fundamental biological phenomenon, in which efficiency depends on several physical parameters. We have engineered a number of horse heart cytochrome c single-point mutants with cysteine substitutions
Externí odkaz:
https://doaj.org/article/25d90bdee2794967bf347ec6ed75cffa
Autor:
Olga V. Bocharova, Aidan Fisher, Narayan P. Pandit, Kara Molesworth, Olga Mychko, Alison J. Scott, Natallia Makarava, Rodney Ritzel, Ilia V. Baskakov
Publikováno v:
Brain Pathology. 33
The possibility that the etiology of late onset Alzheimer's disease is linked to viral infections of the CNS has been actively debated in recent years. According to the antiviral protection hypothesis, viral pathogens trigger aggregation of Aβ pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d02c25121f4c462bb96b315625a5a1e
https://doi.org/10.1111/bpa.13116
https://doi.org/10.1111/bpa.13116
Autor:
Olga V Bocharova, Elizaveta D Kulaeva, E. V. Mashkina, Elena D Teplakova, Mikhail Shkurat, Ekaterina Derevyanchuk, Varvara V Volchik
Publikováno v:
Genetic Testing and Molecular Biomarkers. 25:419-425
Background: Obesity is one of the most common metabolic disorders in the world, which develops due to an imbalance in energy consumption and expenditure, and both genetic and environmental factors ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86dcb3a578605686efa41c7c7f5f440
https://doi.org/10.1089/gtmb.2020.0343
https://doi.org/10.1089/gtmb.2020.0343
Autor:
Yaroslav V. Bershatsky, Andrey S. Kuznetsov, Aisha R. Idiatullina, Olga V. Bocharova, Sofya M. Dolotova, Alina A. Gavrilenkova, Oxana V. Serova, Igor E. Deyev, Tatiana V. Rakitina, Olga T. Zangieva, Konstantin V. Pavlov, Oleg V. Batishchev, Vladimir V. Britikov, Sergey A. Usanov, Alexander S. Arseniev, Roman G. Efremov, Eduard V. Bocharov
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3906
Volume 24
Issue 4
Pages: 3906
Human InsR, IGF1R, and IRR receptor tyrosine kinases (RTK) of the insulin receptor subfamily play an important role in signaling pathways for a wide range of physiological processes and are directly associated with many pathologies, including neurode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e893ba9e447dbe99879cc948cd9e5b83
https://doi.org/10.3390/ijms24043906
https://doi.org/10.3390/ijms24043906
Autor:
Eduard V, Bocharov, Lothar, Gremer, Anatoly S, Urban, Ivan S, Okhrimenko, Pavel E, Volynsky, Kirill D, Nadezhdin, Olga V, Bocharova, Daniil A, Kornilov, Yuliya A, Zagryadskaya, Anna V, Kamynina, Pavel K, Kuzmichev, Janine, Kutzsche, Najoua, Bolakhrif, Andreas, Müller-Schiffmann, Norbert A, Dencher, Alexander S, Arseniev, Roman G, Efremov, Valentin I, Gordeliy, Dieter, Willbold
Publikováno v:
Journal of medicinal chemistry. 64(22)
Alzheimer's disease (AD) is a severe neurodegenerative pathology with no effective treatment known. Toxic amyloid-β peptide (Aβ) oligomers play a crucial role in AD pathogenesis. All
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5734610a5dba17c95b40542793d2c19e
https://pubmed.ncbi.nlm.nih.gov/34739758
https://pubmed.ncbi.nlm.nih.gov/34739758
Autor:
Katalin Tenger, Olga V. Bocharova, Dmitry A. Dolgikh, Géza I. Groma, Alexander Kotlyar, Rita V. Chertkova, László Zimányi, Natalia Borovok, Mikhail P. Kirpichnikov, Petro Khoroshyy
Publikováno v:
Molecules, Vol 26, Iss 6976, p 6976 (2021)
Molecules; Volume 26; Issue 22; Pages: 6976
Molecules; Volume 26; Issue 22; Pages: 6976
Electron transfer within and between proteins is a fundamental biological phenomenon, in which efficiency depends on several physical parameters. We have engineered a number of horse heart cytochrome c single-point mutants with cysteine substitutions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b244c4c32ee77f6f076457990d8b89a
https://www.mdpi.com/1420-3049/26/22/6976
https://www.mdpi.com/1420-3049/26/22/6976
Autor:
Roman G. Efremov, Anatoly S. Urban, Kirill D. Nadezhdin, Konstantin V. Pavlov, Alexander S. Arseniev, Pavel E. Volynsky, Eduard V. Bocharov, Olga V. Bocharova
Publikováno v:
ACS Chemical Biology. 14:1573-1582
Alzheimer's disease is an age-related pathology associated with accumulation of amyloid-β peptides, products of enzymatic cleavage of amyloid-β precursor protein (APP) by secretases. Several familial mutations causing early onset of the disease hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a072e33396eb30cbe162abf16b5169
https://doi.org/10.1021/acschembio.9b00309
https://doi.org/10.1021/acschembio.9b00309
Autor:
Anatoly S. Urban, Amélie I. Velghe, Roman G. Efremov, Bojan Zagrovic, Andrey S. Kuznetsov, Eduard V. Bocharov, Olga V. Bocharova, Anton A. Polyansky, Alexander S. Arseniev, Jean-Baptiste Demoulin
Publikováno v:
Biochimica et biophysica acta. General subjects, Vol. 1863, no.1, p. 82-95 (2019)
Single-point mutations in the transmembrane (TM) region of receptor tyrosine kinases (RTKs) can lead to abnormal ligand-independent activation. We use a combination of computational modeling, NMR spectroscopy and cell experiments to analyze in detail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1793a64e4ca2a9afdc7d65e0faa43b
https://doi.org/10.1016/j.bbagen.2018.09.011
https://doi.org/10.1016/j.bbagen.2018.09.011
Autor:
Kara Molesworth, Olga Mychko, Ilia V. Baskakov, Natallia Makarava, Olga V. Bocharova, Narayan P. Pandit, Aidan Fisher
Publikováno v:
The Journal of Biological Chemistry
Alzheimer’s disease (AD) is a devastating fatal neurodegenerative disease. An alternative to the amyloid cascade hypothesis is that a viral infection is key to the etiology of late-onset AD, with β-amyloid (Aβ) peptides playing a protective role.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ae24230b04d4f7e95d10a7a69a49ed
http://europepmc.org/articles/PMC8214219
http://europepmc.org/articles/PMC8214219