Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Olga Tayber"'
Autor:
Siegfried Janz, Brian Van Ness, Joseph B. Bolen, Mark Manfredi, Erik Kupperman, Allison J. Berger, Vishala T. Neppalli, Mary Carsillo, Paul Hales, Ping Li, Olga Tayber, Zhi Li, Michael Pickard, Ray Liu, Matthew D. Silva, Ozlem Subakan, Daniel P. Bradley, Jennifer Terkelsen, Kristen Bano, Jill Donelan, Bret Bannerman, Michael Fitzgerald, Edmund C. Lee
Purpose: The clinical success of the first-in-class proteasome inhibitor bortezomib (VELCADE) has validated the proteasome as a therapeutic target for treating human cancers. MLN9708 is an investigational proteasome inhibitor that, compared with bort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf51cd992431bfa10c2e6773dbd8053
https://doi.org/10.1158/1078-0432.c.6520107
https://doi.org/10.1158/1078-0432.c.6520107
Autor:
Siegfried Janz, Brian Van Ness, Joseph B. Bolen, Mark Manfredi, Erik Kupperman, Allison J. Berger, Vishala T. Neppalli, Mary Carsillo, Paul Hales, Ping Li, Olga Tayber, Zhi Li, Michael Pickard, Ray Liu, Matthew D. Silva, Ozlem Subakan, Daniel P. Bradley, Jennifer Terkelsen, Kristen Bano, Jill Donelan, Bret Bannerman, Michael Fitzgerald, Edmund C. Lee
PDF file - 108K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fd400a1ca08e8405e5d218dd1e0d4b
https://doi.org/10.1158/1078-0432.22444227.v1
https://doi.org/10.1158/1078-0432.22444227.v1
Autor:
Eric S. Lightcap, Michael A. Milhollen, Usha Narayanan, Ray Liu, Greg Hather, Olga Tayber, Hugues Bernard, Khristofer Garcia, David C. Bouck, Katherine Cosmopoulos, Xiaozhen J. Liu, Jonathan L. Blank
PDF file - 162K, Genes Selected Based upon Extreme BI Scores are More Likely to Have Extreme Deconvoluted Oligo Scores than Those Selected Based upon Biology or Randomly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a546b38d3161caa049609d1965ddbb2
https://doi.org/10.1158/0008-5472.22398225.v1
https://doi.org/10.1158/0008-5472.22398225.v1
Autor:
Eric S. Lightcap, Michael A. Milhollen, Usha Narayanan, Ray Liu, Greg Hather, Olga Tayber, Hugues Bernard, Khristofer Garcia, David C. Bouck, Katherine Cosmopoulos, Xiaozhen J. Liu, Jonathan L. Blank
PDF file - 121K, Distribution and Reproducibility of Scores from SMARTpool Interactions with MLN4924 in A375 Melanoma Cell Line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f144047eabd9043d95d4f04431497b
https://doi.org/10.1158/0008-5472.22398228
https://doi.org/10.1158/0008-5472.22398228
Autor:
Eric S. Lightcap, Michael A. Milhollen, Usha Narayanan, Ray Liu, Greg Hather, Olga Tayber, Hugues Bernard, Khristofer Garcia, David C. Bouck, Katherine Cosmopoulos, Xiaozhen J. Liu, Jonathan L. Blank
PDF file - 355K, Effect of Gene Knock-down on Cell Cycle Distribution of A375 Melanoma Cells in Combination with Vehicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199495bee9c83d595b42944e802ad2d6
https://doi.org/10.1158/0008-5472.22398222.v1
https://doi.org/10.1158/0008-5472.22398222.v1
Autor:
Eric S. Lightcap, Michael A. Milhollen, Usha Narayanan, Ray Liu, Greg Hather, Olga Tayber, Hugues Bernard, Khristofer Garcia, David C. Bouck, Katherine Cosmopoulos, Xiaozhen J. Liu, Jonathan L. Blank
PDF file - 156K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04aebea301b880bdaf5010454e3172ba
https://doi.org/10.1158/0008-5472.22398219
https://doi.org/10.1158/0008-5472.22398219
Autor:
Eric S. Lightcap, Michael A. Milhollen, Usha Narayanan, Ray Liu, Greg Hather, Olga Tayber, Hugues Bernard, Khristofer Garcia, David C. Bouck, Katherine Cosmopoulos, Xiaozhen J. Liu, Jonathan L. Blank
PDF file - 337K, Analysis of flow cytometry results of the effect of vehicle (DMSO) or 3 muM MLN4924 for 24 h on multiple cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563207fc10cacbf53697247f513f68ef
https://doi.org/10.1158/0008-5472.22398231
https://doi.org/10.1158/0008-5472.22398231
Autor:
Eric S. Lightcap, Michael A. Milhollen, Usha Narayanan, Ray Liu, Greg Hather, Olga Tayber, Hugues Bernard, Khristofer Garcia, David C. Bouck, Katherine Cosmopoulos, Xiaozhen J. Liu, Jonathan L. Blank
XLS file - 4.1MB, Summary of Genome-wide siRNA Screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ac2bc280246274b16608310e62f516
https://doi.org/10.1158/0008-5472.22398216
https://doi.org/10.1158/0008-5472.22398216
Autor:
Eric S. Lightcap, Michael A. Milhollen, Usha Narayanan, Ray Liu, Greg Hather, Olga Tayber, Hugues Bernard, Khristofer Garcia, David C. Bouck, Katherine Cosmopoulos, Xiaozhen J. Liu, Jonathan L. Blank
PDF file - 1.6MB, Full Length Western Blots in Support of Figures 4 and 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f4d131f15ef381083561d54789e676
https://doi.org/10.1158/0008-5472.22398234
https://doi.org/10.1158/0008-5472.22398234
Autor:
Yosuke Sato, Cierra N. Casson, Atsushi Matsuda, James I. Kim, Judy Qiuju Shi, Shinji Iwasaki, Susan Chen, Brett Modrell, Chingkit Chan, Daniel Tavares, Douglas Austen, Koh Ida, Olga Tayber, Pyae Hein, Robert Comeau, Yafang Lin, Michael H. Shaw
Publikováno v:
Cancer Immunology, Immunotherapy. 71:2421-2431
Ipilimumab, a monoclonal antibody that recognizes cytotoxic T-lymphocyte associated protein 4 (CTLA-4), was the first immune checkpoint inhibitor approved by the FDA to treat metastatic melanoma patients. Multiple preclinical studies have proposed th