Minimal residual disease status is the prognostic determinant following high‐dose treatment for patients with multiple myeloma

Autor: Hareth Nahi, Gabriel Afram, Katarina Uttervall, Sandra Lockmer, Love Tätting, Gösta Gahrton, Muhammad Kashif, Evren Alici, Olga Stromberg, Monika Klimkowska, Johan Lund

Publikováno v: Cancer Medicine, Vol 12, Iss 22, Pp 20736-20744 (2023)

Abstract Background The presence of minimal residual disease (MRD+) following autologous stem cell transplantation (ASCT) in multiple myeloma represents a poor prognostic factor for progression‐free survival (PFS) and overall survival (OS). Methods

Externí odkaz: https://doaj.org/article/1903be302e0e4ca7b07df80c300622ad

Trametinib and Dabrafenib in histiocytic sarcoma transdifferentiated from chronic lymphocytic leukemia with a K-RAS and a unique BRAF mutation

Autor: Kristina Sonnevi, Ioanna Xagoraris, Kenbugul Jatta, Olga Stromberg, George Z. Rassidakis

Publikováno v: Annals of Hematology. 99:649-651

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f9716da8050f599120fbef380fd1567
https://doi.org/10.1007/s00277-020-03941-7

Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial

Autor: Meletios A Dimopoulos, Francesca Gay, Fredrik Schjesvold, Meral Beksac, Roman Hajek, Katja Christina Weisel, Hartmut Goldschmidt, Vladimir Maisnar, Philippe Moreau, Chang Ki Min, Agnieszka Pluta, Wee-Joo Chng, Martin Kaiser, Sonja Zweegman, Maria-Victoria Mateos, Andrew Spencer, Shinsuke Iida, Gareth Morgan, Kaveri Suryanarayan, Zhaoyang Teng, Tomas Skacel, Antonio Palumbo, Ajeeta B Dash, Neeraj Gupta, Richard Labotka, S Vincent Rajkumar, Daniel Bar, Alfredo Basso, Dorotea Fantl, Simon He, Neomi Horvath, Cindy Lee, Phillip Rowlings, Kerry Taylor, Tara Cochrane, Fiona Kwok, Sundreswran Ramanathan, Hermine Agis, Niklas Zojer, Alain Kentos, Fritz Offner, Jan Van Droogenbroeck, Ka Lung Wu, Angelo Maiolino, Gracia Martinez, Karla Zanella, Marcelo Capra, Sérgio Araújo, Evzen Gregora, Ludek Pour, Vlastimil Scudla, Ivan Spicka, Niels Abildgaard, Niels Andersen, Bo Amdi Jensen, Carsten Helleberg, Torben Plesner, Morten Salomo, Asta Svirskaite, Richard Delarue, Igor Blau, Aneta Schieferdecker, Veronica Teleanu, Markus Munder, Christoph Röllig, Han-Juergen Salwender, Stephan Fuhrmann, Katja Weisel, Jan Duerig, Matthias Zeis, Stefan Klein, Peter Reimer, Christian Schmidt, Christof Scheid, Karin Mayer, Martin Hoffmann, Markus Sosada, Athanasios Dimopoulos, Sosana Delimpasi, Mary-Christine Kyrtsonis, Achilleas Anagnostopoulos, Zsolt Nagy, Árpád Illés, Miklós Egyed, Zita Borbényi, Gabor Mikala, Najib Dally, Netanel Horowitz, Odit Gutwein, Anatoly Nemets, Iuliana Vaxman, Olga Shvetz, Svetlana Trestman, Rosa Ruchlemer, Arnon Nagler, Tamar Tadmor, Ory Rouvio, Meir Preis, Michele Cavo, Luca De Rosa, Pellegrino Musto, Anna Cafro, Patrizia Tosi, Massimo Offidani, Alessandro Corso, Giuseppe Rossi, Anna Marina Liberati, Alberto Bosi, Kenshi Suzuki, Chiaki Nakaseko, Takayuki Ishikawa, Morio Matsumoto, Hirokazu Nagai, Kazutaka Sunami, Takaaki Chou, Koichi Akashi, Naoki Takezako, Shotaro Hagiwara, Hyeon Seok Eom, Deog-Yeon Jo, Jin Seok Kim, Jae Hoon Lee, Sung Soo Yoon, Dok Hyun Yoon, Kihyun Kim, Mark-David Levin, Edo Vellenga, Monique Minnema, Anders Waage, Einar Haukås, Sebastian Grosicki, Andrzej Pluta, Tadeusz Robak, Herlander Marques, Rui Bergantim, Fernando Campilho, Wee Joo Chng, Yeow Tee Goh, Andrew McDonald, Bernado Rapoport, Miguel Angel Álvarez Rivas, Felipe De Arriba de La Fuente, Yolanda González Montes, Jesus Martin Sanchez, Maria Victoria Mateos, Albert Oriol Rocafiguera, Laura Rosinol, Jesús San Miguel, Jaime Pérez de Oteyza, Cristina Encinas, Adrian Alegre-Amor, Ana López-Guía, Per Axelsson, Kristina Carlson, Olga Stromberg, Markus Hansson, Cecile Hveding Blimark, Rouven Mueller, Chih-Cheng Chen, Ta-Chih Liu, Shang-Yi Huang, Po-Nan Wang, Thanyaphong Na Nakorn, Kannadit Prayongratana, Ali Unal, Hakan Goker, Mehmet Sonmez, Sybiryna Korenkova, Aristeidis Chaidos, Heather Oakervee, Hamdi Sati, Reuben Benjamin, Ashutosh Wechalekar, Mamta Garg, Karthik Ramasamy, Gordon Cook, Andrew Chantry, Matthew Jenner, Francis Buadi, Robert Berryman, Murali Janakiram

Publikováno v: Dimopoulos, M A, Gay, F, Schjesvold, F, Beksac, M, Hajek, R, Weisel, K C, Goldschmidt, H, Maisnar, V, Moreau, P, Min, C K, Pluta, A, Chng, W-J, Kaiser, M, Zweegman, S, Mateos, M-V, Spencer, A, Iida, S, Morgan, G, Suryanarayan, K, Teng, Z, Skacel, T, Palumbo, A, Dash, A B, Gupta, N, Labotka, R, Rajkumar, S V, Abildgaard, N & TOURMALINE-MM3 study group 2019, ' Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3) : a double-blind, randomised, placebo-controlled phase 3 trial ', Lancet, vol. 393, no. 10168, pp. 253-264 . https://doi.org/10.1016/S0140-6736(18)33003-4
Dimopoulos, M A, Gay, F, Schjesvold, F, Beksac, M, Hajek, R, Weisel, K C, Goldschmidt, H, Maisnar, V, Moreau, P, Min, C K, Pluta, A, Chng, W J, Kaiser, M, Zweegman, S, Mateos, M V, Spencer, A, Iida, S, Morgan, G, Suryanarayan, K, Teng, Z, Skacel, T, Palumbo, A, Dash, A B, Gupta, N, Labotka, R, Rajkumar, S V, Kwok, F & TOURMALINE-MM3 study group 2019, ' Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3) : a double-blind, randomised, placebo-controlled phase 3 trial ', The Lancet, vol. 393, no. 10168, pp. 253-264 . https://doi.org/10.1016/S0140-6736(18)33003-4
Digital.CSIC. Repositorio Institucional del CSIC
instname
Lancet, 393(10168), 253. Elsevier Limited
LANCET, 393(10168), 253-264. ELSEVIER SCIENCE INC
The Lancet, 393(10168), 253-264. Elsevier Limited

[Background]: Maintenance therapy following autologous stem cell transplantation (ASCT) can delay disease progression and prolong survival in patients with multiple myeloma. Ixazomib is ideally suited for maintenance therapy given its convenient once

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de353f2eca3bce4266841424f74a30c
http://hdl.handle.net/2318/1732833

Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation in Sweden, long-term results from all patients treated in 1994-2009

Autor: Olga Stromberg, Karin Forsberg, Sara Rosengren, Hareth Nahi, U. H. Mellqvist, Lucia Ahlberg, Stig Lenhoff, Kristina Carlson, Olle Linder

Publikováno v: Bone marrow transplantation. 51(12)

High-dose melphalan and autologous stem cell transplantation (HDM/ASCT) is widely used in immunoglobulin light chain (AL) amyloidosis, but the benefit is debated mainly because of the high treatment-related mortality (24% in a randomised study compar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86984baf0cf0eabb95d1086f8f8e0bcc
https://pubmed.ncbi.nlm.nih.gov/27694943