Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Olga Stakhovskaya"'
Publikováno v:
Hearing Research. 342:134-143
Many previous studies have shown significant neurotrophic effects of intracochlear delivery of BDNF in preventing degeneration of cochlear spiral ganglion (SG) neurons after deafness in rodents and our laboratory has shown similar results in developi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bc41bf82a1c4495c3f8b1a200fcbce
https://doi.org/10.1016/j.heares.2016.10.011
https://doi.org/10.1016/j.heares.2016.10.011
Autor:
Meral Gunay-Aygun, William A. Gahl, Hung Jeffrey Kim, Kelly A. King, Juergen K Naggert, Jan D. Marshall, Joy Bryant, Carmen C. Brewer, Spencer Lindsey, Olga Stakhovskaya, Chris Zalewski
Publikováno v:
American journal of medical genetics. Part A. 173(8)
Alström syndrome is a rare autosomal recessive ciliopathy caused by mutations in the ALMS1 gene. Hallmark characteristics include childhood onset of severe retinal degeneration, sensorineural hearing loss, obesity, insulin-resistant diabetes, and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cd15d84678dad42ce1fdb5c004db9b
https://pubmed.ncbi.nlm.nih.gov/28573831
https://pubmed.ncbi.nlm.nih.gov/28573831
Publikováno v:
The Journal of Comparative Neurology. 519:1526-1545
Postnatal development and survival of spiral ganglion (SG) neurons depend on both neural activity and neurotrophic support. Our previous studies showed that electrical stimulation from a cochlear implant only partially prevents SG degeneration after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364ee32744a2555c0ac3f33311ca17db
https://doi.org/10.1002/cne.22582
https://doi.org/10.1002/cne.22582
Spontaneous Discharge Patterns in Cochlear Spiral Ganglion Cells Before the Onset of Hearing in Cats
Publikováno v:
Journal of Neurophysiology. 98:1898-1908
Spontaneous neural activity has been recorded in the auditory nerve of cats as early as 2 days postnatal (P2), yet individual auditory neurons do not respond to ambient sound levels i = 2.9 ± 1.6) and burst index of 5.2 ± 3.5 across ganglion cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b867a2eb67bdea41ed0fb57461a34d
https://doi.org/10.1152/jn.00472.2007
https://doi.org/10.1152/jn.00472.2007
This study examined the effects of deafness and intracochlear electrical stimulation on the anatomy of the cochlear nucleus (CN) after a brief period of normal auditory development early in life. Kittens were deafened by systemic ototoxic drug inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc7ff3fd051a962ae90f4d4889a0bb1
https://europepmc.org/articles/PMC2575007/
https://europepmc.org/articles/PMC2575007/
Publikováno v:
Hearing research. 242(1-2)
Research in animal models has demonstrated that electrical stimulation from a cochlear implant (CI) may help prevent degeneration of the cochlear spiral ganglion (SG) neurons after deafness. In cats deafened early in life, effective stimulation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d49ffe0b81cdb17810415f63fc1d2d7
https://pubmed.ncbi.nlm.nih.gov/18573324
https://pubmed.ncbi.nlm.nih.gov/18573324