Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Olga Senkovich"'
Autor:
Elias Seif, Jin Joo Kang, Charles Sasseville, Olga Senkovich, Alexander Kaltashov, Elodie L. Boulier, Ibani Kapur, Chongwoo A. Kim, Nicole J. Francis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
The conserved SAM motif of Polycomb Repressive Complex 1 subunit Ph has been shown to play an important role in chromatin organization. Here, the authors study the effect of Ph SAM on chromatin in vitro, showing that it induces the formation of conce
Externí odkaz:
https://doaj.org/article/f93773e13b25400184a9e8d15645342f
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46875 (2012)
Pyruvate kinase plays a critical role in cellular metabolism of glucose by serving as a major regulator of glycolysis. This tetrameric enzyme is allosterically regulated by different effector molecules, mainly phosphosugars. In response to binding of
Externí odkaz:
https://doaj.org/article/1254262e68124f01a58c29da12ed655b
Autor:
Alexander Kaltashov, Elodie L. Boulier, Jin Joo Kang, Elias Seif, Chongwoo A. Kim, Charles Sasseville, Ibani Kapur, Olga Senkovich, Nicole J. Francis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications
Nature Communications
Polycomb Group (PcG) proteins organize chromatin at multiple scales to regulate gene expression. A conserved Sterile Alpha Motif (SAM) in the Polycomb Repressive Complex 1 (PRC1) subunit Polyhomeotic (Ph) has been shown to play an important role in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0d91e76d90bef838a1946fc4975677
http://link.springer.com/article/10.1038/s41467-020-19435-z
http://link.springer.com/article/10.1038/s41467-020-19435-z
Autor:
Kelsey N. Abel, Jason A. Artigas, Andrew P. Hinck, Olga Senkovich, Micah D. Gearhart, Sarah J. Wong, David W. Graham, Udayar Ilangovan, Tianrong Yu, Chongwoo A. Kim, Vivian J. Bardwell
Publikováno v:
Biochemistry
Polycomb repression complex 1 (PRC1) is a multiprotein assembly that regulates transcription. The Polycomb group ring finger 1 protein (PCGF1) is central in the assembly of the noncanonical PRC1 variant called PRC1.1 through its direct interaction wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed9c988921d6b6114c63d72b8dfc257
https://doi.org/10.1021/acs.biochem.0c00285
https://doi.org/10.1021/acs.biochem.0c00285
Autor:
Olga Senkovich, Joseph R. Gould, Rachael Motamed, Surajit Banerjee, Todd Green, Norbert Schormann, Juan Campos, Debasish Chattopadhyay, Glen C. Ulett, Katherine L. Hayden
Publikováno v:
Protein Sci
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an evolutionarily conserved essential enzyme in the glycolytic pathway. GAPDH is also involved in a wide spectrum of non-catalytic cellular 'moonlighting' functions. Bacterial surface-associated GAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e024cc9fcacafb5f137bc0b9b35ab26c
https://europepmc.org/articles/PMC7679969/
https://europepmc.org/articles/PMC7679969/
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
The protozoan parasite Cryptosporidium parvum causes waterborne diseases worldwide. There is no effective therapy for C. parvum infection. The parasite depends mainly on glycolysis for energy production. Lactate dehydrogenase is a major regulator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a622b3f91d1f116806d44130cb6e67
https://doi.org/10.1016/j.ijbiomac.2014.12.019
https://doi.org/10.1016/j.ijbiomac.2014.12.019
Autor:
Norbert Schormann, Surajit Banerjee, Debasish Chattopadhyay, Chapelle A. Ayres, Alexandra Fry, Glen C. Ulett, Olga Senkovich
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 70:1333-1339
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a conserved cytosolic enzyme, which plays a key role in glycolysis. GAPDH catalyzes the oxidative phosphorylation of D-glyceraldehyde 3-phosphate using NAD or NADP as a cofactor. In addition, GAPDH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14f25bb115c57952ee4fc37cb0131d2
https://doi.org/10.1107/s2053230x14019517
https://doi.org/10.1107/s2053230x14019517
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67:1339-1344
The crystal structure of the catalytic domain of the ADP ribosylation factor GTPase-activating protein (ARFGAP) from Plasmodium falciparum has been determined and refined to 2.4 Å resolution. Multiwavength anomalous diffraction (MAD) data were colle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f079be38183644d5df6d82886a6e8289
https://doi.org/10.1107/s1744309111032507
https://doi.org/10.1107/s1744309111032507
Autor:
Robert E. Rhoads, David J. McGee, Carolyn Conant, Sergey V. Slepenkov, James G. Traylor, Traci L. Testerman, Viktoriya Ekshyyan, Olga Senkovich, Jun Yin, Patrick Adegboyega
Publikováno v:
Infection and Immunity. 79:3106-3116
Helicobacter pylori persistently colonizes humans, causing gastritis, ulcers, and gastric cancer. Adherence to the gastric epithelium has been shown to enhance inflammation, yet only a few H. pylori adhesins have been paired with targets in host tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047fd097449f3c6e79be1228b1700834
https://doi.org/10.1128/iai.01275-10
https://doi.org/10.1128/iai.01275-10
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 66:1426-1431
Vesicular trafficking may play a crucial role in the pathogenesis and survival of the malaria parasite. ADP-ribosylation factors (ARFs) are among the major components of vesicular trafficking pathways in eukaryotes. The crystal structure of ARF1 GTPa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953980558703e323fcc3dcb5075a8f5d
https://doi.org/10.1107/s1744309110036997
https://doi.org/10.1107/s1744309110036997