Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Olga Savichtcheva"'
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Early, On-Treatment Levels and Dynamic Changes of Genomic Instability in Circulating Tumor DNA Predict Response to Treatment and Outcome in Metastatic Breast Cancer Patients
Autor: Josiane P. Lafleur, Graham McLennan, Nathan Faulkner, Susie Brousse, Olga Savichtcheva, Kimberly A. Holden, Taylor J. Jensen, Mark Basik, Adriana Aguilar-Mahecha
Publikováno v: Cancers
Volume 13
Issue 6
Cancers, Vol 13, Iss 1331, p 1331 (2021)
Background: Circulating tumor DNA (ctDNA) offers high sensitivity and specificity in metastatic cancer. However, many ctDNA assays rely on specific mutations in recurrent genes or require the sequencing of tumor tissue, difficult to do in a metastati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9590bbdfdf5f66b9a2fb03a4abae1930
https://doi.org/10.3390/cancers13061331
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2
Abstract 2149: Use of PDXs and patient-derived cell lines to uncover unconventional drug therapies and combinations for the treatment of drug-resistant cancers
Autor: Urszula Krzemien, Gerald Batist, Jean-Francois Boileau, Paul Savage, Catherine Chabot, Cathy Lan, Morag Park, Adriana Aguilar-Mahecha, Olga Savichtcheva, Marguerite Buchanan, Josiane P. Lafleur, Mark Basik, Cristiano Ferrario
Publikováno v: Cancer Research. 78:2149-2149
The use of patient derived models for pre-clinical drug testing provides a unique opportunity for testing non-conventional therapies and novel drug combinations to overcome drug resistance in cancer. We have established 22 models from breast cancer,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::524a77b52a059e91778586e4140cd6d6
https://doi.org/10.1158/1538-7445.am2018-2149
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3
Relationships between Bacteroides 16S rRNA genetic markers and presence of bacterial enteric pathogens and conventional fecal indicators
Autor: Satoshi Okabe, Olga Savichtcheva, Noriko Okayama
Publikováno v: Water Research. 41:3615-3628
Occurrence and prevalence of different bacterial enteric pathogens as well as their relationships with conventional (total and fecal coliforms) and alternative fecal indicators (host-specific Bacteroides 16S rRNA genetic markers) were investigated fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ed6e9036db55eea9a74b9e53ba6c6e
https://doi.org/10.1016/j.watres.2007.03.028
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4
Effects of nutrients and warming on Planktothrix dynamics and diversity: a palaeolimnological view based on sedimentary DNA and RNA
Autor: Isabelle Domaizon, Emilie Lyautey, Benjamin Alric, Amy Kirkham, Clement Villar, Marie-Elodie Perga, Fabien Arnaud, Didier Debroas, Cécile Chardon, Olga Savichtcheva
Publikováno v: Freshwater Biology
Freshwater Biology, Wiley, 2015, 60 (1), pp.31-49. ⟨10.1111/fwb.12465⟩
Freshwater Biology, 2015, 60 (1), pp.31-49. ⟨10.1111/fwb.12465⟩
Summary Decennial changes in Planktothrix rubescens diversity and dynamics were reconstructed by applying molecular tools to analyse DNA and RNA extracted from lake sediments. The sediments studied were sampled from a deep peri-alpine lake that has e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a640c99ed04a318ba66dccf3c49aa1
https://hal.archives-ouvertes.fr/hal-01452304
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5
Alternative indicators of fecal pollution: Relations with pathogens and conventional indicators, current methodologies for direct pathogen monitoring and future application perspectives
Autor: Olga Savichtcheva, Satoshi Okabe
Publikováno v: Water Research. 40:2463-2476
The ecological and survival characteristics of bacterial, viral and parasitic pathogens vary under environmental conditions, indicating that probably no single indicator organism can predict the presence of all enteric pathogens for all types of wate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506a392c9ee040850c58175d2f5d0d2c
https://doi.org/10.1016/j.watres.2006.04.040
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6
Trophic transfer of microcystins through the lake pelagic food web: evidence for the role of zooplankton as a vector in fish contamination
Autor: Jean Guillard, Benoît Sotton, Marjorie Maréchal, Olga Savichtcheva, Isabelle Domaizon, Orlane Anneville
Publikováno v: The Science of the total environment.
An in situ study was performed to investigate the role of zooplankton as a vector of microcystins (MCs) from Planktothrix rubescens filaments to fish during a metalimnic bloom of P. rubescens in Lake Hallwil (Switzerland). The concentrations of MCs i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08737cc0417eedd64a490ce417cecc6c
https://pubmed.ncbi.nlm.nih.gov/23906853
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7
DNA from lake sediments reveals the long-term dynamics and diversity of Synechococcus assemblages
Autor: Benjamin Alric, Olga Savichtcheva, Isabelle Domaizon, Didier Debroas, Marie-Elodie Perga, Clement Villar, Fabien Arnaud, Cécile Pignol
While picocyanobacteria (PC) are important actors in carbon and nutrient cycles in aquatic systems, factors controlling their interannual dynamics and diversity are poorly known due to the general lack of long-term monitoring surveys. This study inte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cc86bf7bce73a1ec318ce1800104e7
https://doi.org/10.5194/bgd-10-2515-2013
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10
Quantitative PCR enumeration of total/toxic Planktothrix rubescens and total cyanobacteria in preserved DNA isolated from lake sediments
Autor: Fabien Arnaud, Jean-Philippe Jenny, Olga Savichtcheva, Didier Debroas, Rainer Kurmayer, Isabelle Domaizon, Clement Villar, Marie-Elodie Perga
Publikováno v: Applied and Environmental Microbiology
Applied and Environmental Microbiology, American Society for Microbiology, 2011, 77 (24), pp.8744-53. ⟨10.1128/AEM.06106-11⟩
Applied and Environmental Microbiology, 2011, 77 (24), pp.8744-53. ⟨10.1128/AEM.06106-11⟩
The variability of spatial distribution and the determinism of cyanobacterial blooms, as well as their impact at the lake scale, are still not understood, partly due to the lack of long-term climatic and environmental monitoring data. The paucity of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a78965c76804d52202ccee7fa3f344
https://hal.archives-ouvertes.fr/hal-00840945
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