Accurate and fast identification of minimally prepared bacteria phenotypes using Raman spectroscopy assisted by machine learning

Autor: Benjamin Lundquist Thomsen, Jesper B. Christensen, Olga Rodenko, Iskander Usenov, Rasmus Birkholm Grønnemose, Thomas Emil Andersen, Mikael Lassen

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract The worldwide increase of antimicrobial resistance (AMR) is a serious threat to human health. To avert the spread of AMR, fast reliable diagnostics tools that facilitate optimal antibiotic stewardship are an unmet need. In this regard, Raman

Externí odkaz: https://doaj.org/article/87193caef5994f92993e18f173c9d451

Accurate identification of bacteria in a minimally prepared environment using Raman spectroscopy assisted by machine learning

Autor: Benjamin Thomsen, Jesper Christensen, Olga Rodenko, Iskander Usenov, Rasmus B. Grønnemose, Thomas Emil Andersen, Mikael Ø. Lassen

Publikováno v: Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2023.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27845429ddebafd54e4217a9674f6f0a
https://doi.org/10.1117/12.2646653

340nm UV LED excitation in time-resolved fluorescence system for europium-based immunoassays detection

Autor: Olga Rodenko, Henrik Fodgaard, Christian Pedersen, Peter Tidemand-Lichtenberg

Publikováno v: Rodenko, O, Fodgaard, H, Tidemand-Lichtenberg, P & Pedersen, C 2017, 340nm UV LED excitation in time-resolved fluorescence system for europium-based immunoassays detection . in Proceedings of SPIE . vol. 10072, 100720M, SPIE-International Society for Optical Engineering, Proceedings of SPIE-The International Society for Optical Engineering, Optical Diagnostics and Sensing XVII: Toward Point-of-Care Diagnostics, San Francisco, California, United States, 30/01/2017 . https://doi.org/10.1117/12.2250769

In immunoassay analyzers for in-vitro diagnostics, Xenon flash lamps have been widely used as excitation light sources. Recent advancements in UV LED technology and its advantages over the flash lamps such as smaller footprint, better wall-plug effic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3556c3c5d492c6cc2a4d34b75fa39a09
https://doi.org/10.1117/12.2250769

340 nm pulsed UV LED system for europium-based time-resolved fluorescence detection of immunoassays

Autor: Henrik Fodgaard, Peter Tidemand-Lichtenberg, Paul Michael Petersen, Christian Pedersen, Olga Rodenko

Publikováno v: Rodenko, O, Fodgaard, H, Tidemand-Lichtenberg, P, Petersen, P M & Pedersen, C 2016, ' 340 nm pulsed UV LED system for europium-based time-resolved fluorescence detection of immunoassays ', Optics Express, vol. 24, no. 19, pp. 22135-22143 . https://doi.org/10.1364/OE.24.022135

We report on the design, development and investigation of an optical system based on UV light emitting diode (LED) excitation at 340 nm for time-resolved fluorescence detection of immunoassays. The system was tested to measure cardiac marker Troponin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c45976124183844853402e03959638a
https://pubmed.ncbi.nlm.nih.gov/27661948

Efficient simulation of autofluorescence effects in microscopic lenses

Autor: Olga Rodenko, Herbert Gross, Moritz Esslinger, Andreas Tünnermann

Publikováno v: Gross, H, Rodenko, O, Esslinger, M & Tünnermann, A 2015, Efficient simulation of autofluorescence effects in microscopic lenses . in Proceedings of SPIE . vol. 9626, 962609, SPIE-International Society for Optical Engineering, Proceedings of SPIE-The International Society for Optical Engineering, Optical Design and Engineering, Jena, Germany, 07/09/2015 . https://doi.org/10.1117/12.2191260

The use of fluorescence in microscopy is a well known technology today. Due to the autofluorescence of the materials of the optical system components, the contrast of the images is degraded. The calculation of autofluorescense usually is performed by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef50030ce0c30556febf28c4a93b790
https://doi.org/10.1117/12.2191260