Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Olga Renner"'
Autor:
Alban Piotrowsky, Markus Burkard, Katharina Hammerschmidt, Hannah K. Ruple, Pia Nonnenmacher, Monika Schumacher, Christian Leischner, Susanne Berchtold, Luigi Marongiu, Thomas A. Kufer, Ulrich M. Lauer, Olga Renner, Sascha Venturelli
Publikováno v:
Antioxidants, Vol 13, Iss 9, p 1095 (2024)
Several studies have demonstrated, both in vitro and in animal models, the anti-tumor efficacy of high-dose ascorbate treatment against a variety of tumor entities, including glioblastoma, the most common and aggressive primary malignant brain tumor.
Externí odkaz:
https://doaj.org/article/0e0ee2440fab426a82a3784ac1036db3
Autor:
Christian Leischner, Luigi Marongiu, Alban Piotrowsky, Heike Niessner, Sascha Venturelli, Markus Burkard, Olga Renner
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 916 (2023)
Despite the increasing number of newly diagnosed malignancies worldwide, therapeutic options for some tumor diseases are unfortunately still limited. Interestingly, preclinical but also some clinical data suggest that the administration of pharmacolo
Externí odkaz:
https://doaj.org/article/056c09e84ea54a1ba84c561177d2aa0e
Autor:
Markus Burkard, Heike Niessner, Christian Leischner, Alban Piotrowsky, Olga Renner, Luigi Marongiu, Ulrich M. Lauer, Christian Busch, Tobias Sinnberg, Sascha Venturelli
Publikováno v:
Cells, Vol 12, Iss 2, p 254 (2023)
Ascorbate acts as a prooxidant when administered parenterally at high supraphysiological doses, which results in the generation of hydrogen peroxide in dependence on oxygen. Most cancer cells are susceptible to the emerging reactive oxygen species (R
Externí odkaz:
https://doaj.org/article/748f1d6dd3e54c14b47d1ac01c5f0e50
Autor:
Tobias Sinnberg, Christa Lichtensteiger, Katharina Hill-Mündel, Christian Leischner, Heike Niessner, Christian Busch, Olga Renner, Nina Wyss, Lukas Flatz, Ulrich M. Lauer, Ludwig E. Hoelzle, Donatus Nohr, Markus Burkard, Luigi Marongiu, Sascha Venturelli
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1580 (2022)
Coronavirus disease 2019 (COVID-19) is the most notable pandemic of the modern era. A relationship between ascorbate (vitamin C) and COVID-19 severity is well known, whereas the role of other vitamins is less understood. The present study compared th
Externí odkaz:
https://doaj.org/article/a03a10598ea946df810d82b974e25561
Autor:
Mascha Mayer, Alexander Berger, Christian Leischner, Olga Renner, Markus Burkard, Alexander Böcker, Seema Noor, Timo Weiland, Thomas S. Weiss, Christian Busch, Ulrich M. Lauer, Stephan C. Bischoff, Sascha Venturelli
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 438 (2022)
Gossypol, a sesquiterpenoid found in cotton seeds, exerts anticancer effects on several tumor entities due to inhibition of DNA synthesis and other mechanisms. In clinical oncology, histone deacetylase inhibitors (HDACi) are applied as anticancer com
Externí odkaz:
https://doaj.org/article/09e8460e1a33471d8ee405bb420c8aef
Autor:
Heike Niessner, Markus Burkard, Christian Leischner, Olga Renner, Sarah Plöger, Francisco Meraz-Torres, Matti Böcker, Constanze Hirn, Ulrich M. Lauer, Sascha Venturelli, Christian Busch, Tobias Sinnberg
Publikováno v:
Cells, Vol 11, Iss 7, p 1229 (2022)
High-dose ascorbate paradoxically acts as a pro-oxidant causing the formation of hydrogen peroxide in an oxygen dependent manner. Tumor cells (in particular melanoma cells) show an increased vulnerability to ascorbate induced reactive oxygen species
Externí odkaz:
https://doaj.org/article/ac50fc3fb9854c4399ee807731d5d2d5
Autor:
Olga Renner, Mascha Mayer, Christian Leischner, Markus Burkard, Alexander Berger, Ulrich M. Lauer, Sascha Venturelli, Stephan C. Bischoff
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 144 (2022)
The potential of gossypol and of its R-(−)-enantiomer (R-(−)-gossypol acetic acid, AT-101), has been evaluated for treatment of cancer as an independent agent and in combination with standard chemo-radiation-therapies, respectively. This review a
Externí odkaz:
https://doaj.org/article/fb4bed0651c1488aacf328ecde69ba2d
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 9, Pp 2045-2054 (2008)
Cholelithiasis is a multifactorial process, and several mechanisms have been postulated. A decreased expression of the ileal apical sodium-dependent bile acid transporter (ASBT) and of the cytosolic ileal lipid binding protein (ILBP) was recently des
Externí odkaz:
https://doaj.org/article/4219762d2fd04ab2b916d478091a413a
Autor:
Olga Renner, Simone Harsch, Elke Schaeffeler, Stefan Winter, Matthias Schwab, Marcin Krawczyk, Jonas Rosendahl, Henning Wittenburg, Frank Lammert, Eduard F Stange
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7321 (2009)
BACKGROUND:Cholelithiasis is a multifactorial process and several mechanisms of gallstone formation have been postulated. As one of these mechanisms, a decreased expression of the ileal apical sodium-dependent bile acid transporter gene SLC10A2 in ga
Externí odkaz:
https://doaj.org/article/8078fa531ce048cfb99aa0197462a7e7
Autor:
Venturelli, Tobias Sinnberg, Christa Lichtensteiger, Katharina Hill-Mündel, Christian Leischner, Heike Niessner, Christian Busch, Olga Renner, Nina Wyss, Lukas Flatz, Ulrich M. Lauer, Ludwig E. Hoelzle, Donatus Nohr, Markus Burkard, Luigi Marongiu, Sascha
Publikováno v:
Antioxidants; Volume 11; Issue 8; Pages: 1580
Coronavirus disease 2019 (COVID-19) is the most notable pandemic of the modern era. A relationship between ascorbate (vitamin C) and COVID-19 severity is well known, whereas the role of other vitamins is less understood. The present study compared th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::1dacd1368bc3b300f34d5e8913029b31