Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Olga Pernía"'
Autor:
Rocío Rosas-Alonso, Julian Colmenarejo-Fernández, Olga Pernía, Miranda Burdiel, Carlos Rodríguez-Antolín, Itsaso Losantos-García, Tania Rubio, Rocío Moreno-Velasco, Isabel Esteban-Rodríguez, Virginia Martínez-Marín, Paloma Yubero, Nicolas Costa-Fraga, Angel Díaz-Lagares, Rafael López-López, Eva Díaz-Martin, Juan F. García, Catalina Vivancos Sánchez, Maria Luisa Gandía-González, Gema Moreno-Bueno, Javier de Castro, Inmaculada Ibánez de Cáceres
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Glioblastoma (GB) is a devastating tumor of the central nervous system characterized by a poor prognosis. One of the best-established predictive biomarker in IDH-wildtype GB is O6-methylguanine-DNA methyltransferase (MGMT) methylation (mMGMT
Externí odkaz:
https://doaj.org/article/e4a8484a046145d48a70e38e2c8d1575
Autor:
Miranda Burdiel, Julia Jiménez, Carlos Rodríguez-Antolín, Álvaro García-Guede, Olga Pernía, Ana Sastre-Perona, Rocío Rosas-Alonso, Julián Colmenarejo, Carmen Rodríguez-Jiménez, María Dolores Diestro, Virginia Martínez-Marín, Oliver Higueras, Patricia Cruz, Itsaso Losantos-García, Héctor Peinado, Olga Vera, Javier de Castro, Inmaculada Ibáñez de Cáceres
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract Small extracellular vesicles (sEVs) in the blood of cancer patients contain higher amounts of tumor markers than those identified as free-circulating. miRNAs have significant biomedical relevance due to their high stability and feasible dete
Externí odkaz:
https://doaj.org/article/fb3fd8538ff04f0a980527d02e7153c5
Autor:
Darío Sanchez-Cabrero, Álvaro Garcia-Guede, Miranda Burdiel, Olga Pernía, Julián Colmenarejo-Fernandez, Laura Gutierrez, Oliver Higuera, Isabel Esteban Rodriguez, Rocío Rosas-Alonso, Carlos Rodriguez-Antolín, Itsaso Losantos-García, Olga Vera, Javier De Castro-Carpeño, Inmaculada Ibanez de Caceres
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11464 (2023)
Despite advances in non-small cell lung cancer (NSCLC) research, this is still the most common cancer type that has been diagnosed up to date. microRNAs have emerged as useful clinical biomarkers in both tissue and liquid biopsy. However, there are n
Externí odkaz:
https://doaj.org/article/c82e7bcbdbe64a4e99943c7310982c98
Autor:
Carlos Rodríguez-Antolín, Laura Felguera-Selas, Olga Pernía, Olga Vera, Isabel Esteban, Itsaso Losantos García, Javier de Castro, Rocío Rosas-Alonso, Inmaculada Ibanez de Caceres
Publikováno v:
Cell & Bioscience, Vol 9, Iss 1, Pp 1-6 (2019)
Abstract Non-small-cell lung cancer (NSCLC) is the most common malignancy worldwide. Platinum-based chemotherapy is the standard of care for these patients. Recent research showed that miR-7 methylation status is a biomarker of cisplatin resistance i
Externí odkaz:
https://doaj.org/article/1f94d0872e2e4bb9a3639f57237c1d58
Autor:
Olga Pernía, Ana Sastre-Perona, Carlos Rodriguez-Antolín, Alvaro García-Guede, María Palomares-Bralo, Rocío Rosas, Darío Sanchez-Cabrero, Patricia Cruz, Carmen Rodriguez, MDolores Diestro, Rubén Martín-Arenas, Verónica Pulido, Pilar Santisteban, Javier de Castro, Olga Vera, Inmaculada Ibáñez de Cáceres
Publikováno v:
Cancers, Vol 12, Iss 4, p 786 (2020)
Despite often leading to platinum resistance, platinum-based chemotherapy continues to be the standard treatment for many epithelial tumors. In this study we analyzed and validated the cytogenetic alterations that arise after treatment in four lung a
Externí odkaz:
https://doaj.org/article/f768a3a0d3914a3bbe01bf683d18af49
Autor:
Javier Benitez, Inmaculada Ibáñez de Cáceres, Maria Dolores Diestro, Carlos Rodriguez-Antolin, Rafael Alvarez, Fátima Sánchez-Cabo, Javier de Castro, Olga Pernía, Olga Vera, Isabel Esteban-Rodríguez, Javier Andrés Soto
Publikováno v:
Clinical Epigenetics
Repositorio Universidad de Santander
Universidad de Santander
instacron:Universidad de Santander
Repositorio Universidad de Santander
Universidad de Santander
instacron:Universidad de Santander
Digital
Background: In an effort to contribute to overcoming the platinum resistance exhibited by most solid tumors, we performed an array of epigenetic approaches, integrating next-generation methodologies and public clinical data to identify n
Background: In an effort to contribute to overcoming the platinum resistance exhibited by most solid tumors, we performed an array of epigenetic approaches, integrating next-generation methodologies and public clinical data to identify n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165246aa54b2180709bf9f5f1fca76db
https://doi.org/10.1186/s13148-021-01149-8
https://doi.org/10.1186/s13148-021-01149-8
Autor:
Olga Pernía, Sara Palacios-Zambrano, Itsaso Losantos-Garcia, Inmaculada Ibanez-de-caceres, Isabel Esteban, Darío Sanchez-Cabrero, Ismael Ghanem, Virginia Martínez-Marín, Rocío Rosas-Alonso, Carlos Rodriguez-Antolin, Julian Colmenarejo-Fernandez, Gema Moreno-Bueno, Javier de Castro
Publikováno v:
Clinical Epigenetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
© The Author(s) 2021.
[Background]: The promoter hypermethylation of the methylguanine-DNA methyltransferase gene is a frequently used biomarker in daily clinical practice as it is associated with a favorable prognosis in glioblastoma patients
[Background]: The promoter hypermethylation of the methylguanine-DNA methyltransferase gene is a frequently used biomarker in daily clinical practice as it is associated with a favorable prognosis in glioblastoma patients
Autor:
Isabel Esteban, Darío Sanchez-Cabrero, Ismael Ghanem, Carlos Rodriguez-Antolin, Javier de Castro, Julian Colmenarejo-Fernandez, Virginia Martínez-Marín, Rocío Rosas-Alonso, Inmaculada Ibáñez de Cáceres, Itsaso Losantos-Garcia, Olga Pernía
The promoter hypermethylation of the methylguanine-DNA methyltransferase (MGMT) gene is a frequently used biomarker in daily clinical practice as it is associated with a favorable prognosis in glioblastoma patients treated with temozolamide. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2339d159bb50a8fa074bc832bbb7dde7
https://doi.org/10.20944/preprints202008.0096.v1
https://doi.org/10.20944/preprints202008.0096.v1
Autor:
Olga Pernía, Rocío Rosas, Ángel Diaz Lagares, Olga Vera Puente, Patricia Cruz Castellanos, Julia Jimenez, Isabel Esteban, Javier de Castro, Oliver Higuera, Inmaculada Ibáñez De Cáceres, Itsaso Losantos, Tatiana Juste
Publikováno v:
Cancer Research. 81:2095-2095
Background: Non-small cell lung cancer (NSCLC) represents the 80-85% of the lung cancer. Cisplatin-based chemotherapy is the paradigm of NSCLC treatment; however, it also induces de novo DNA hyper methylation that is associated with gene expression r
Autor:
Inmaculada Ibáñez de Cáceres, Rocío Rosas, Carlos Rodriguez-Antolin, Miranda Burdiel, P. Cruz, Darío Sanchez-Cabrero, Itsaso Losantos, Olga Pernía, Julia Jimenez, Javier de Castro
Publikováno v:
Cancer Research. 81:2381-2381
Background: Non-small cell lung cancer (NSCLC) is one leading cause of death worldwide, with a 5-year survival rate of only 24%. Late diagnosis and the innate or acquired anti-cancer drug resistance are the main causes of this high mortality. In rece