Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Olga Pacios"'
Autor:
Antonio Barrio-Pujante, Inés Bleriot, Lucía Blasco, Laura Fernández-Garcia, Olga Pacios, Concha Ortiz-Cartagena, Felipe Fernández Cuenca, Jesús Oteo-Iglesias, María Tomás
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundMultidrug-resistant bacteria and the shortage of new antibiotics constitute a serious health problem. This problem has led to increased interest in the use of bacteriophages, which have great potential as antimicrobial agents but also carry
Externí odkaz:
https://doaj.org/article/d5dafc76cf324a599697e03b661cade3
Autor:
Olga Pacios, Soraya Herrera-Espejo, Lucía Armán, Clara Ibarguren-Quiles, Lucía Blasco, Inés Bleriot, Laura Fernández-García, Concha Ortiz-Cartagena, María Paniagua, Antonio Barrio-Pujante, Belén Aracil, José Miguel Cisneros, María Eugenia Pachón-Ibáñez, María Tomás
Publikováno v:
Antibiotics, Vol 13, Iss 9, p 815 (2024)
The combination of several therapeutic strategies is often seen as a good way to decrease resistance rates, since bacteria can more easily overcome single-drug treatments than multi-drug ones. This strategy is especially attractive when several targe
Externí odkaz:
https://doaj.org/article/e2fb171679d445e89f7e46bded1b6701
Autor:
Olga Pacios, Lucía Blasco, Concha Ortiz Cartagena, Inés Bleriot, Laura Fernández-García, María López, Antonio Barrio-Pujante, Felipe Fernández Cuenca, Belén Aracil, Jesús Oteo-Iglesias, María Tomás
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Mucins are important glycoproteins that form a protective layer throughout the gastrointestinal and respiratory tracts. There is scientific evidence of increase in phage-resistance in the presence of mucin for some bacterial pathogens. Manipulation i
Externí odkaz:
https://doaj.org/article/8cafde59190d4bc3928d67c064bf2a75
Autor:
Lucía Blasco, Manuel González de Aledo, Concha Ortiz-Cartagena, Inés Blériot, Olga Pacios, María López, Laura Fernández-García, Antonio Barrio-Pujante, Marta Hernández-Garcia, Rafael Cantón, María Tomás
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Phage tail-like bacteriocins (PTLBs) are large proteomic structures similar to the tail phages. These structures function in bacterial competition by making pores in the membrane of their competitors. The PTLBs identified in Pseudomonas aeru
Externí odkaz:
https://doaj.org/article/f990ec9ee74d48049db080727ac741ae
Autor:
Manuel González de Aledo, Lucia Blasco, Maria Lopez, Concha Ortiz-Cartagena, Inés Bleriot, Olga Pacios, Marta Hernández-García, Rafael Cantón, Maria Tomas
Publikováno v:
mSphere, Vol 8, Iss 4 (2023)
ABSTRACT Prophages are bacteriophages integrated into the bacterial host’s chromosome. This research aims to analyze and characterize the existing prophages within a collection of 53 Pseudomonas aeruginosa strains from intensive care units (ICUs) i
Externí odkaz:
https://doaj.org/article/024dfe003a6f4267bd0ea08700975492
Autor:
Concha Ortiz-Cartagena, Daniel Pablo-Marcos, Laura Fernández-García, Lucía Blasco, Olga Pacios, Inés Bleriot, María Siller, María López, Javier Fernández, Belén Aracil, Pablo Arturo Fraile-Ribot, Sergio García-Fernández, Felipe Fernández-Cuenca, Marta Hernández-García, Rafael Cantón, Jorge Calvo-Montes, María Tomás
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Carbapenem-resistant pathogens have been recognized as a health concern as they are both difficult to treat and detect in clinical microbiology laboratories. Researchers are making great efforts to develop highly specific, sensitive, accurat
Externí odkaz:
https://doaj.org/article/84bc09a95f104ef695408a888a0ea7d7
Autor:
Manuela C. Aguirre-Botero, Eduardo Aliprandini, Anisha Gladston, Olga Pacios, Rafael Miyazawa Martins, Jean-Luc Poyet, Rogerio Amino
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 480 (2024)
Membranolytic molecules constitute the first line of innate immune defense against pathogenic microorganisms. Plasmodium sporozoites are potentially exposed to these cytotoxic molecules in the hemolymph and salivary glands of mosquitoes, as well as i
Externí odkaz:
https://doaj.org/article/4f5d4429d3264601ad82e325d1de34de
Autor:
Ines Bleriot, Lucia Blasco, Olga Pacios, Laura Fernández-García, Antón Ambroa, María López, Concha Ortiz-Cartagena, Felipe Fernández Cuenca, Jesús Oteo-Iglesias, Álvaro Pascual, Luis Martínez-Martínez, Pilar Domingo-Calap, Thomas K. Wood, María Tomás
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Since their discovery, toxin-antitoxin (TA) systems have captivated the attention of many scientists. Recent studies have demonstrated that TA systems play a key role in phage inhibition. The aim of the present study was to investigate the r
Externí odkaz:
https://doaj.org/article/8d0634cffb1c40989205c9d200451c72
Autor:
Concha Ortiz-Cartagena, Laura Fernández-García, Lucia Blasco, Olga Pacios, Inés Bleriot, María López, Rafael Cantón, María Tomás
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT At the end of 2019, a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), caused a pandemic that persists to date and has resulted in more than 6.2 million deaths. In the last couple of years, researchers have made
Externí odkaz:
https://doaj.org/article/0cf5f349c9ff4afba2ecf32d81d0e03c
Autor:
Antón Ambroa, Lucia Blasco, María López, Olga Pacios, Inés Bleriot, Laura Fernández-García, Manuel González de Aledo, Concha Ortiz-Cartagena, Andrew Millard, María Tomás
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
To optimize phage therapy, we need to understand how bacteria evolve against phage attacks. One of the main problems of phage therapy is the appearance of bacterial resistance variants. The use of genomics to track antimicrobial resistance is increas
Externí odkaz:
https://doaj.org/article/42cf4cb1edf04d4d8102f5e67f1b28a7