Biochemical Properties of a Promising Milk-Clotting Enzyme, Moose (Alces alces) Recombinant Chymosin

Autor: Dina V. Balabova, Ekaterina A. Belash, Svetlana V. Belenkaya, Dmitry N. Shcherbakov, Alexander N. Belov, Anatoly D. Koval, Anna V. Mironova, Alexander A. Bondar, Ekaterina A. Volosnikova, Sergey G. Arkhipov, Olga O. Sokolova, Varvara Y. Chirkova, Vadim V. Elchaninov

Publikováno v: Foods, Vol 12, Iss 20, p 3772 (2023)

Moose (Alces alces) recombinant chymosin with a milk-clotting activity of 86 AU/mL was synthesized in the Kluyveromyces lactis expression system. After precipitation with ammonium sulfate and chromatographic purification, a sample of genetically engi

Externí odkaz: https://doaj.org/article/b17bc991ef924f16b5ba870c8ca9ee26

C–C Bond Activations of Minimally Activated Cyclopropanes

Autor: John F. Bower, Olga O. Sokolova, Andrew G. Dalling

Publikováno v: Synlett.

Catalytic processes involving oxidative addition of a C–C bond to a transition metal allow the atom economical assembly of complex scaffolds. The focus of this Account is on C–C bond activation-based methodologies that employ minimally activated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4daa6e1b289d1a23ac284e56e8b1b770
https://doi.org/10.1055/s-0042-1753177

Stereocontrolled Synthesis of Fluorinated Isochromans via Iodine(I)/Iodine(III) Catalysis

Autor: Joel Häfliger, Olga O. Sokolova, Madina Lenz, Constantin G. Daniliuc, Ryan Gilmour

Publikováno v: Angewandte Chemie (International ed. in English). 61(30)

The success of saturated, fluorinated heterocycles in contemporary drug discovery provides a stimulus for creative endeavor in main group catalysis. Motivated by the ubiquity of isochromans across the bioactive small molecule spectrum, the prominence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2ada4dd7da704465d7f93299003d11
https://pubmed.ncbi.nlm.nih.gov/35536157

Carbonylative C–C Bond Activation of Aminocyclopropanes Using a Temporary Directing Group Strategy

Autor: Tom A. Young, Gang-Wei Wang, Ektor M. S. Christodoulou, Olga O. Sokolova, Craig P. Butts, John F. Bower

Publikováno v: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Wang, G-W, Sokolova, O O, Young, T A, Christodoulou, E M S, Butts, C P & Bower, J F 2020, ' Carbonylative C–C Bond Activation of Aminocyclopropanes Using a Temporary Directing Group Strategy ', Journal of the American Chemical Society, vol. 142, no. 45, pp. 19006–19011 . https://doi.org/10.1021/jacs.0c08973

Temporary directing groups (TDGs) underpin a range of C-C bond activation methodologies; however, the use of TDGs for the regiocontrolled activation of cyclopropane C-C bonds is underdeveloped. In this report, we show how an unusual ring contraction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159ea4738507f662113200b500eb9af8
https://doi.org/10.1021/jacs.0c08973

Electrocatalytic Cascade Reaction of Aldehydes and 4-Hydroxy-6-methyl-2H-pyran-2-one

Autor: Fructuoso Barba, Alexander D. Korshunov, Michail N. Elinson, Belen Batanero, Olga O. Sokolova

Publikováno v: Electrocatalysis. 9:602-607

The electrolysis of salicylaldehydes and 4-hydroxy-6-methyl-2H-pyran-2-one in an undivided cell in alcoholic media and in the presence of alkali metal halides results in rapid and efficient formation of the substituted 3-acetoacetylcoumarins in 85–

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bef74ac485c6a1905dab561121a4c9a
https://doi.org/10.1007/s12678-018-0470-6