Production of Bst polymerase for diagnosis of different infections using loop-mediated isothermal amplification

Autor: Maria I. Pika, Olga O. Mikheeva, Elena D. Solovyova, Anna V. Valdokhina, Victoria P. Bulanenko, Evgeny A. Cherkashin, Vadim V. Petrov, Kirill V. Krasovitov, Anna S. Cherkashina, Vasily G. Akimkin

Publikováno v: Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 100, Iss 3, Pp 210-218 (2023)

Introduction. The large fragment of DNA polymerase I from Geobacillus stearothermophilus GIM1.543 (Bst DNA polymerase) possesses 5'-3' DNA polymerase activity, 5'-3' displacement activity and high processivity. These properties make it possible to us

Externí odkaz: https://doaj.org/article/7401a923d4be4c649ebf919317306af1

The comparative analysis of the properties and structures of purine nucleoside phosphorylases from thermophilic bacterium Thermus thermophilus HB27

Autor: Vladimir I. Timofeev, I. V. Fateev, Y.A. Abramchik, Irina D. Konstantinova, Inna P. Kuranova, T. I. Muravieva, D. D. Lykoshin, Vladimir Volkov, Roman S. Esipov, M. A. Kostromina, Olga O Mikheeva

Publikováno v: Journal of Biomolecular Structure and Dynamics. 40:3626-3641

Two recombinant purine nucleoside phosphorylases from thermophilic bacterium Thermus thermophilus HB27 encoded by genes TT_C1070 (TthPNPI) and TT_C0194 (TthPNPII) were purified and characterized. T...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d27c24510a7643a0196d4e1ece1b8b32
https://doi.org/10.1080/07391102.2020.1848628

Multi-Enzymatic Cascades in the Synthesis of Modified Nucleosides: Comparison of the Thermophilic and Mesophilic Pathways

Autor: Elena V Dorofeeva, Alexander S. Paramonov, Y.A. Abramchik, Dmitry D Lukoshin, Irina D. Konstantinova, Barbara Z. Eletskaya, Roman S. Esipov, Evgeniy A Zayats, Maria Ya Berzina, M. A. Kostromina, Olga O Mikheeva, Alexey L Kayushin, Ilja V. Fateev

Publikováno v: Biomolecules, Vol 11, Iss 586, p 586 (2021)
Biomolecules
Volume 11
Issue 4

A comparative study of the possibilities of using ribokinase → phosphopentomutase → nucleoside phosphorylase cascades in the synthesis of modified nucleosides was carried out. Recombinant phosphopentomutase from Thermus thermophilus HB27 was obta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f6ff43731ec7ad2eecda5bb12c31a6
https://pubmed.ncbi.nlm.nih.gov/33923608

A Randomized, Phase III Trial to Evaluate Rucaparib Monotherapy as Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer (ATHENA-MONO/GOG-3020/ENGOT-ov45).

Autor: Monk BJ; GOG Foundation, HonorHealth Research Institute, University of Arizona College of Medicine, Creighton University School of Medicine, Phoenix, AZ., Parkinson C; Medical Oncology, Addenbrooke's Hospital, Cambridge, United Kingdom., Lim MC; Gynecologic Oncology, National Cancer Center Korea, Goyang-si, Gyeonggi-do, South Korea., O'Malley DM; Division of Gynecologic Oncology, The Ohio State University, James Cancer Center, Columbus, OH., Oaknin A; Gynaecologic Cancer Programme, Vall d'Hebron Institute of Oncology (VHIO), Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Wilson MK; Department of Cancer and Blood, Auckland City Hospital, Auckland, New Zealand., Coleman RL; US Oncology Research, The Woodlands, TX., Lorusso D; MITO and Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS and Catholic University of Sacred Heart, Rome, Italy., Bessette P; Department of Obstetrics and Gynecology, University of Sherbrooke, Sherbrooke, Quebec, Canada., Ghamande S; Department of Obstetrics and Gynecology, Augusta University, Augusta, GA., Christopoulou A; Medical Oncology, St Andrews General Hospital, Patras, Greece., Provencher D; Princess Margaret Consortium and Department of Obstetrics-Gynaecology, Centre Hospitalier de l'Université de Montréal (CHUM), Institut du Cancer de Montréal, Montréal, Canada., Prendergast E; Gynecologic Oncology, Minnesota Oncology and Metro-Minnesota Community Oncology Research Consortium, Minneapolis, MN., Demirkiran F; Gynecologic Oncology Department, Medical Faculty, Istanbul University, Cerrahpaşa, Istanbul, Turkey., Mikheeva O; Limited Liability Company MedPomosch, Saint Petersburg, Russia., Yeku O; Gynecologic Cancers Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Chudecka-Glaz A; Department of Gynecological Surgery and Gynecological Oncology of Adults and Adolescents, Pomeranian Medical University, Szczecin, Poland., Schenker M; Department of Medical Oncology, Sfantul Nectarie Oncology Center, Dolj, Romania., Littell RD; Kaiser Permanente Northern California Gynecologic Cancer Program, San Francisco, CA., Safra T; Oncology Department, Tel Aviv Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Chou HH; Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital (Linkou), Tao-Yuan, Taiwan.; College of Life Science, National Tsing Hua University, Hsinchu, Taiwan., Morgan MA; Division of Gynecologic Oncology, University of Pennsylvania Health System, Philadelphia, PA., Drochýtek V; Department of Obstetrics and Gynaecology, Faculty Hospital Kralovske Vinohrady, 3rd Medical Faculty, Charles University, Prague, Czech Republic., Barlin JN; Women's Cancer Care Associates, Division of Gynecologic Oncology, Albany Medical College, Albany, NY., Van Gorp T; Division of Gynaecological Oncology, Department of Obstetrics and Gynecology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium., Ueland F; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of Kentucky, Lexington, KY., Lindahl G; Nordic Society of Gynaecological Oncology, Copenhagen, Denmark.; Department of Oncology, Linköping University, Linköping, Sweden., Anderson C; Department of Gynecologic Oncology, Willamette Valley Cancer Institute and Research Center, Eugene, OR., Collins DC; Cancer Trials Ireland and Department of Medical Oncology, Cork University Hospital, Cork, Ireland., Moore K; Stevenson Cancer Center at the University of Oklahoma Health Sciences Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK., Marme F; AGO and Department Obstetrics and Gynecology, University Hospital Mannheim, Mannheim, Germany., Westin SN; Department of Gynecologic Oncology and Reproductive Medicine, University of Texas MD Anderson Cancer Center, Houston, TX., McNeish IA; Department of Surgery and Cancer, Imperial College London, London, United Kingdom., Shih D; Clinical Operations, Clovis Oncology Inc, Boulder, CO., Lin KK; Molecular Diagnostics, Clovis Oncology Inc, Boulder, CO., Goble S; Biostatistics, Clovis Oncology Inc, Boulder, CO., Hume S; Clinical Development, Clovis Oncology Inc, Boulder, CO., Fujiwara K; Department of Gynecologic Oncology, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan., Kristeleit RS; Department of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2022 Dec 01; Vol. 40 (34), pp. 3952-3964. Date of Electronic Publication: 2022 Jun 06.