Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Olga N. Solovjeva"'
Autor:
Olga N. Solovjeva
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2068
Volume 24
Issue 3
Pages: 2068
Transketolase catalyzes the interconversion of keto and aldo sugars. Its coenzyme is thiamine diphosphate. The binding of keto sugar with thiamine diphosphate is possible only after C2 deprotonation of its thiazole ring. It is believed that deprotona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef29a21880acc7e1d85a809c842f957
https://doi.org/10.3390/ijms24032068
https://doi.org/10.3390/ijms24032068
Publikováno v:
Molecular Catalysis. 466:122-129
For baker’s yeast transketolase (TK), cooperative binding of thiamine diphosphate (ThDP) and substrates in the transferase reaction is known. We show here that the differences in the properties of the active centers of TK are formed already upon th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a1aceb3187c673447b07dfd8ccf052a
https://doi.org/10.1016/j.mcat.2019.01.008
https://doi.org/10.1016/j.mcat.2019.01.008
Autor:
Dmitrii S Shcherbinin, Olga N. Solovjeva, German A. Kochetov, Victor G. Zgoda, Maria G. Zavialova, Marina V. Kovina
Publikováno v:
Bioscience Reports
Transketolase catalyzes the transfer of a glycolaldehyde residue from ketose (the donor substrate) to aldose (the acceptor substrate). In the absence of aldose, transketolase catalyzes a one-substrate reaction that involves only ketose. The mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aae2d4afe10d3a7221011da1832ea28
http://europepmc.org/articles/PMC7403953
http://europepmc.org/articles/PMC7403953
Autor:
Olga N. Solovjeva
Publikováno v:
Analytical Biochemistry. 613:114022
In a recent paper, we showed the difference between the first stage of the one-substrate and the two-substrate transketolase reactions - the possibility of transfer of glycolaldehyde formed as a result of cleavage of the donor substrate from the thia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d56dc909dbfad8afd313087ea3ecc58
https://doi.org/10.1016/j.ab.2020.114022
https://doi.org/10.1016/j.ab.2020.114022
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832(3):387-390
Until recently it was assumed that the transketolase-like protein (TKTL1) detected in the tumor tissue, is catalytically active mutant form of human transketolase (hTKT). Human TKT shares 61% sequence identity with TKTL1. And the two proteins are 77%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c5b5e914f0d6441067004ab5079890
Autor:
Vladimir A. Yurshev, German A. Kochetov, Vitalii A. Selivanov, Olga N. Solovjeva, Irina A. Sevostyanova
Publikováno v:
The Protein Journal. 31:137-140
Catalytic activity has been demonstrated for holotransketolase in the absence of free bivalent cations in the medium. The two active centers of the enzyme are equivalent in both the catalytic activity and the affinity for the substrates. In the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::588ec505854ca0d83d2c2018c3178088
https://doi.org/10.1007/s10930-011-9382-5
https://doi.org/10.1007/s10930-011-9382-5
Autor:
Gema Alcarraz-Vizán, Pedro Vizán, Olga N. Solovjeva, Marta Cascante, Wilma M. Frederiks, Santiago Diaz-Moralli
Publikováno v:
International Journal of Cancer. 124:2789-2796
Cell cycle regulation is dependent on multiple cellular and molecular events. Cell proliferation requires metabolic sources for the duplication of DNA and cell size. However, nucleotide reservoirs are not sufficient to support cell duplication and, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9486a7a9acb7e4828c206df43f696b71
https://doi.org/10.1002/ijc.24262
https://doi.org/10.1002/ijc.24262
Autor:
Philip W. Kuchel, German A. Kochetov, Antonio Ramos-Montoya, Marta Cascante, L. E. Meshalkina, Olga N. Solovjeva, Vitaly A. Selivanov, Paul W. N. Lee
Publikováno v:
Bioinformatics. 21:3558-3564
Motivation: Addition of labeled substrates and the measurement of the subsequent distribution of the labels in isotopomers in reaction networks provide a unique method for assessing metabolic fluxes in whole cells. However, owing to insufficiency of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dde6373eb0b0545f715bb67f7f52538
https://doi.org/10.1093/bioinformatics/bti573
https://doi.org/10.1093/bioinformatics/bti573
Autor:
Olga N. Solovjeva
Publikováno v:
Biochemistry (Moscow). 67:667-671
A method for isolation of homogenous transketolase from baker's yeast using immunoaffinity chromatography was significantly simplified. It was demonstrated that transketolase could be isolated from fresh yeast in the form of a complex with a high mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7960210ad91ccd0e64030c687cf691c0
https://doi.org/10.1023/a:1016198321838
https://doi.org/10.1023/a:1016198321838
Autor:
Olga N. Solovjeva, German A. Kochetov
Publikováno v:
Biochimica et biophysica acta. 1844(9)
Studies of thiamine diphosphate-dependent enzymes appear to have commenced in 1937, with the isolation of the coenzyme of yeast pyruvate decarboxylase, which was demonstrated to be a diphosphoric ester of thiamine. For quite a long time, these studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7342ba6c0a92a69af9e58eb133c32995
https://pubmed.ncbi.nlm.nih.gov/24929114
https://pubmed.ncbi.nlm.nih.gov/24929114