Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Olga Mokina"'
Autor:
Darya Tsibulskaya, Svetlana Dubiley, Julia Piskunova, Olga Mokina, Konstantin Severinov, Marina V. Serebryakova, Alexey Kulikovsky
Publikováno v:
Journal of the American Chemical Society. 139(45)
Microcin C is a heptapeptide-adenylate antibiotic produced by some strains of Escherichia coli. Its peptide part is responsible for facilitated transport inside sensitive cells where it is proteolyzed with release of a toxic warhead-a nonhydrolyzable
Autor:
Arthur Van Aerschot, Darya Tsibulskaya, Alexey Kulikovsky, Svetlana Dubiley, Olga Mokina, Manesh Nautiyal, Marina V. Serebryakova, Konstantin Severinov
Publikováno v:
Journal of the American Chemical Society
Microcin C and related antibiotics are Trojan-horse peptide-adenylates. The peptide part is responsible for facilitated transport inside the sensitive cell, where it gets processed to release a toxic warhead—a nonhydrolyzable aspartyl-adenylate, wh