Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Olga M. Mazina"'
Autor:
Nadish Goyal, Matthew J. Rossi, Olga M. Mazina, Yong Chi, Robert L. Moritz, Bruce E. Clurman, Alexander V. Mazin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
RAD54 stimulates activity of the RAD51 recombinase and catalyzes branch migration of Holliday junctions during DNA repair and recombination. Here the authors show that the N-terminal domain of RAD54 mediates RAD54 oligomerization to promote branch mi
Externí odkaz:
https://doaj.org/article/b15bd6aeba5249c9abdcd8a19d96755d
Autor:
Alexander V. Mazin, Olga M. Mazina
Publikováno v:
Homologous Recombination ISBN: 9781071606438
Methods Mol Biol
Methods Mol Biol
Rad54 is a eukaryotic protein that plays an important role in homologous recombination. Rad54, a member of the Swi2/Snf2 family, binds to Holliday junctions with high specificity and promotes their branch migration in an ATP hydrolysis-dependent mann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bae83a10ee1690186e9ab5a9f0f0193
https://doi.org/10.1007/978-1-0716-0644-5_11
https://doi.org/10.1007/978-1-0716-0644-5_11
Autor:
Andrey G. Baranovskiy, Tahir H. Tahirov, Farid A. Kadyrov, Lyudmila Y. Kadyrova, Alexander V. Mazin, Srinivas Somarowthu, Olga M. Mazina
Publikováno v:
J Biol Chem
Replication protein A (RPA), a major eukaryotic ssDNA-binding protein, is essential for all metabolic processes that involve ssDNA, including DNA replication, repair, and damage signaling. To perform its functions, RPA binds ssDNA tightly. In contras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef37093b994af6fd015b77ffb6ce690
https://doi.org/10.1101/2020.02.11.943977
https://doi.org/10.1101/2020.02.11.943977
Autor:
Gabor Banyai, Alli L. Gombolay, Chance Meers, Gary P. Newnam, Taehwan Yang, Havva Keskin, Alexander V. Mazin, Efiyenia I. Kaparos, Olga M. Mazina, Francesca Storici
Publikováno v:
SSRN Electronic Journal.
DNA double-strand breaks (DSBs) are dangerous lesions threatening genomic stability. Fidelity of DSB repair is best achieved by recombination with a homologous template sequence. In yeast, transcript RNA was shown to template DSB repair of chromosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c65a16744d49896cce682a6009599a0
https://doi.org/10.2139/ssrn.3517554
https://doi.org/10.2139/ssrn.3517554
Autor:
Kuntal Mukherjee, Chance Meers, Alli L. Gombolay, Francesca Storici, Gabor Banyai, Gary P. Newnam, Havva Keskin, Efiyenia I. Kaparos, Olga M. Mazina, Taehwan Yang, Alexander V. Mazin
Publikováno v:
Mol Cell
DNA double-stranded breaks (DSBs) are dangerous lesions threatening genomic stability. Fidelity of DSB repair is best achieved by recombination with a homologous template sequence. In yeast, transcript RNA was shown to template DSB repair of DNA. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ce6a381b69848a73f7428c25adef48
https://pubmed.ncbi.nlm.nih.gov/32882183
https://pubmed.ncbi.nlm.nih.gov/32882183
Autor:
Alexander V. Mazin, Nadish Goyal, Olga M. Mazina, Matthew J. Rossi, Bruce E. Clurman, Yong Chi, Robert L. Moritz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature Communications
In eukaryotes, RAD54 catalyzes branch migration (BM) of Holliday junctions, a basic process during DNA repair, replication, and recombination. RAD54 also stimulates RAD51 recombinase and has other activities. Here, we investigate the structural deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236c48f3a028bccec6cbf27ecd4b4a9f
http://link.springer.com/article/10.1038/s41467-017-02497-x
http://link.springer.com/article/10.1038/s41467-017-02497-x
Autor:
Kritika Hanamshet, Tomasz Skorski, Mikir Patel, Nadish Goyal, Alexander V. Mazin, Olga M. Mazina, James Spoonamore, Shailesh Metkar, Katherine J. Sullivan, Kyle A. Emmitte, Charles X. Wang, Simon Cocklin, W. Frank An, Fei Huang
Publikováno v:
Nucleic Acids Research
RAD52 is a member of the homologous recombination (HR) pathway that is important for maintenance of genome integrity. While single RAD52 mutations show no significant phenotype in mammals, their combination with mutations in genes that cause heredita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eeb922ca0ba07183807d03b76e45014
https://doi.org/10.1093/nar/gkw087
https://doi.org/10.1093/nar/gkw087
Autor:
Alexander V. Mazin, Olga M. Mazina
Publikováno v:
Methods in enzymology. 600
Proteins of the Rad51 family play a key role in homologous recombination by carrying out DNA strand exchange. Here, we present the methodology and the protocols for the 4-strand exchange between gapped circular DNA and homologous linear duplex DNA pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2a33904d533ab455da6acfd6611fe8
https://pubmed.ncbi.nlm.nih.gov/29458763
https://pubmed.ncbi.nlm.nih.gov/29458763
Publikováno v:
Molecular cell. 67(1)
RNA can serve as a template for DNA double-strand break repair in yeast cells, and Rad52, a member of the homologous recombination pathway, emerged as an important player in this process. However, the exact mechanism of how Rad52 contributes to RNA-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509dd83775972ede5d1a4d8c41fb7bcd
https://pubmed.ncbi.nlm.nih.gov/28602639
https://pubmed.ncbi.nlm.nih.gov/28602639