Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Olga Leonova"'
Autor:
Alexander Burov, Ekaterina Grigorieva, Timofey Lebedev, Valeria Vedernikova, Vladimir Popenko, Tatiana Astakhova, Olga Leonova, Pavel Spirin, Vladimir Prassolov, Vadim Karpov, Alexey Morozov
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Introduction: Proteasomes are multi-subunit protein complexes responsible for protein degradation in cells. Immunoproteasomes and intermediate proteasomes (together non-constitutive proteasomes) are specific forms of proteasomes frequently associated
Externí odkaz:
https://doaj.org/article/4934c412afc54464983aec2d3baccb3d
Autor:
Thalia S Field, William J Panenka, Andrea A Jones, Fidel Vila-Rodriguez, Olga Leonova, Donna J Lang, Alasdair M Barr, Alexander Rauscher, Allen E Thornton, William G Honer, Jacob L Stubbs, Daniel Wolfman, Ryan C Y Chan, Alexandra T Vertinsky, Manraj K Heran, Wayne Su, Kristina M Gicas, Melissa L Woodward, William MacEwan
Publikováno v:
BMJ Neurology Open, Vol 5, Iss 1 (2023)
Background Homeless or precariously housed individuals live with poor health and experience premature mortality compared with the general population, yet little is known about age-related brain changes among these individuals. We evaluated whether MR
Externí odkaz:
https://doaj.org/article/23db8d0d781643039f29b68a1dd9d5b1
Autor:
Lianne L. Cho, Andrea A. Jones, Skye Barbic, Olga Leonova, Fidel Vila-Rodriguez, Tari Buchanan, Donna J. Lang, G. William MacEwan, Ric M. Procyshyn, William J. Panenka, Alasdair M. Barr, Allen E. Thornton, Kristina M. Gicas, William G. Honer
Publikováno v:
Journal of Affective Disorders Reports, Vol 6, Iss , Pp 100229- (2021)
Background: Although homeless or precariously housed populations have a high prevalence of depression, the suitability of existing symptom measurement tools remains unknown. The present study explores the psychometric properties and correlates of the
Externí odkaz:
https://doaj.org/article/2ccb635f3d3a4c2c807279d669d354a4
Autor:
Heather A. Baitz, Paul W. Jones, David A. Campbell, Andrea A. Jones, Kristina M. Gicas, Chantelle J. Giesbrecht, Wendy Loken Thornton, Carmelina C. Barone, Nena Y. Wang, William J. Panenka, Donna J. Lang, Fidel Vila-Rodriguez, Olga Leonova, Alasdair M. Barr, Ric M. Procyshyn, Tari Buchanan, Alexander Rauscher, G. William MacEwan, William G. Honer, Allen E. Thornton
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
The Iowa Gambling Task (IGT) is a widely used measure of decision making, but its value in signifying behaviors associated with adverse, “real-world” consequences has not been consistently demonstrated in persons who are precariously housed or ho
Externí odkaz:
https://doaj.org/article/56d681f3822d436abafebecf37ee7793
Autor:
Andrea A Jones, Kristina M Gicas, Sam Seyedin, Taylor S Willi, Olga Leonova, Fidel Vila-Rodriguez, Ric M Procyshyn, Geoffrey N Smith, Toby A Schmitt, A Talia Vertinsky, Tari Buchanan, Alex Rauscher, Donna J Lang, G William MacEwan, Viviane D Lima, Julio S G Montaner, William J Panenka, Alasdair M Barr, Allen E Thornton, William G Honer
Publikováno v:
PLoS Medicine, Vol 17, Iss 7, p e1003172 (2020)
BACKGROUND:The "trimorbidity" of substance use disorder and mental and physical illness is associated with living in precarious housing or homelessness. The extent to which substance use increases risk of psychosis and both contribute to mortality ne
Externí odkaz:
https://doaj.org/article/afbe8e4f7fbb4414b0162a8e17d4c7fc
Autor:
Kristina M. Gicas, Andrea A. Jones, Allen E. Thornton, Anna Petersson, Emily Livingston, Kristina Waclawik, William J. Panenka, Alasdair M. Barr, Donna J. Lang, Fidel Vila-Rodriguez, Olga Leonova, Ric M. Procyshyn, Tari Buchanan, G. William MacEwan, William G. Honer
Publikováno v:
BJPsych Open, Vol 6 (2020)
BackgroundHomeless and precariously housed individuals experience a high burden of comorbid illnesses, and excess mortality. Cross-sectional studies report a high rate of cognitive impairment. Long-term trajectories have not been well investigated in
Externí odkaz:
https://doaj.org/article/5c80e0f1e3c94f088e2862094badd9a0
Selective Inhibition of HDAC Class I Sensitizes Leukemia and Neuroblastoma Cells to Anticancer Drugs
Autor:
Elmira Vagapova, Maxim Kozlov, Timofey Lebedev, Karina Ivanenko, Olga Leonova, Vladimir Popenko, Pavel Spirin, Sergey Kochetkov, Vladimir Prassolov
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1846 (2021)
The acquired resistance of neuroblastoma (NB) and leukemia cells to anticancer therapy remains the major challenge in the treatment of patients with these diseases. Although targeted therapy, such as receptor tyrosine kinase (RTK) inhibitors, has bee
Externí odkaz:
https://doaj.org/article/0144764414a54097a08eec6554067cae
Autor:
Alexander Burov, Sergei Funikov, Elmira Vagapova, Alexandra Dalina, Alexander Rezvykh, Elena Shyrokova, Timofey Lebedev, Ekaterina Grigorieva, Vladimir Popenko, Olga Leonova, Daria Spasskaya, Pavel Spirin, Vladimir Prassolov, Vadim Karpov, Alexey Morozov
Publikováno v:
Cells, Vol 10, Iss 11, p 3049 (2021)
The degradation of most intracellular proteins is a dynamic and tightly regulated process performed by proteasomes. To date, different forms of proteasomes have been identified. Currently the role of non-constitutive proteasomes (immunoproteasomes (i
Externí odkaz:
https://doaj.org/article/19082ea56f0d4d82a9b1d7c06365760f
Autor:
Kristina Waclawik, Andrea A. Jones, Skye P. Barbic, Kristina M. Gicas, Tiffany A. O'Connor, Geoffrey N. Smith, Olga Leonova, Steve Mathias, Alasdair M. Barr, Ric M. Procyshyn, Donna J. Lang, Melissa L. Woodward, G. William MacEwan, William J. Panenka, Aiko Yamamoto, William G. Honer, Allen E. Thornton
Publikováno v:
Frontiers in Public Health, Vol 7 (2019)
Objective: Homeless and marginally housed youth are particularly vulnerable members of society, and are known to experience numerous health problems, including psychiatric illness, substance use, and viral infection. Despite the presence of these ris
Externí odkaz:
https://doaj.org/article/c2cc4c2b02b64774acc72dd76cc4a99b
Autor:
Kristina M Gicas, Andrea A Jones, William J Panenka, Chantelle Giesbrecht, Donna J Lang, Fidel Vila-Rodriguez, Olga Leonova, Alasdair M Barr, Ric M Procyshyn, Wayne Su, Alexander Rauscher, A Talia Vertinsky, Tari Buchanan, G William MacEwan, Allen E Thornton, William G Honer
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218201 (2019)
IntroductionCognition is impaired in homeless and vulnerably housed persons. Within this heterogeneous and multimorbid group, distinct profiles of cognitive dysfunction are evident. However, little is known about the underlying neurobiological substr
Externí odkaz:
https://doaj.org/article/a7e3ac580f254c419509777162f431c1