Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Olga Konopatskaya"'
Autor:
Alastair W. Poole, Matthew T. Harper, Olga Konopatskaya, Christopher Williams, Joshua Savage, Ingeborg Hers
Publikováno v:
Journal of Thrombosis and Haemostasis. 11:771-775
Autor:
Imke C. A. Munnix, Karen Gilio, Johan W. M. Heemskerk, Alastair W. Poole, Michael Leitges, Lenneke Prinzen, Jeffery D. Molkentin, Matthew T. Harper, Olga Konopatskaya, Judith M.E.M. Cosemans, Qinghang Liu
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry, 285(30), 23408-23417. American Society for Biochemistry and Molecular Biology, Inc.
Journal of Biological Chemistry, 285(30), 23408-23417. American Society for Biochemistry and Molecular Biology, Inc.
Arterial thrombosis, a major cause of myocardial infarction and stroke, is initiated by activation of blood platelets by subendothelial collagen. The protein kinase C (PKC) family centrally regulates platelet activation, and it is becoming clear that
Autor:
Alastair W. Poole, Olga Konopatskaya
Publikováno v:
Trends in Pharmacological Sciences
Protein kinase Calpha (PKCalpha) is a member of the AGC (which includes PKD, PKG and PKC) family of serine/threonine protein kinases that is widely expressed in mammalian tissues. It is closely related in structure, function and regulation to other m
Autor:
Julie V. Macpherson, Jacqueline L. Whatmore, Patrick R. Unwin, Anna L. Barker, Christopher R. Neal, Angela C. Shore, C. Peter Winlove, Olga Konopatskaya
Publikováno v:
Phys. Chem. Chem. Phys.. 6:1006-1011
This paper describes the use of confocal laser scanning microscopy (CLSM) to observe and characterise the fully hydrated glycocalyx of human umbilical vein endothelial cells (HUVECs). Viable HUVECs in primary culture were studied at room temperature
Autor:
Michael Leitges, Alastair W. Poole, Karen Gilio, Matthew T. Harper, Olga Konopatskaya, Deborah A. Carter, Christopher Williams, María N. Navarro, Sharon A. Matthews, Johan W. M. Heemskerk, Doreen A. Cantrell, Judith M.E.M. Cosemans
Publikováno v:
Blood, 118(2), 416-424. The American Society of Hematology
Platelets are highly specialized blood cells critically involved in hemostasis and thrombosis. Members of the protein kinase C (PKC) family have established roles in regulating platelet function and thrombosis, but the molecular mechanisms are not cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00faac51ae811a940dfebf89fa864c34
https://cris.maastrichtuniversity.nl/en/publications/1d04e808-f478-44cd-ac33-e7584b52ae62
https://cris.maastrichtuniversity.nl/en/publications/1d04e808-f478-44cd-ac33-e7584b52ae62
Autor:
Alastair W. Poole, Matthew L. Jones, Matthew T. Harper, Olga Konopatskaya, Lucy MacCarthy-Morrogh
Publikováno v:
Atherosclerosis: Molecular and Cellular Mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4b50f746e8f55aec4af849e34ac6889
https://doi.org/10.1002/9783527629589.ch17
https://doi.org/10.1002/9783527629589.ch17
Autor:
Michael Ladomery, Moin A. Saleem, Amanda J. Churchill, Dawid G. Nowak, Steven J. Harper, Olga Konopatskaya, Elianna M. Amin, David O. Bates, Jeanette Woolard
Vascular endothelial growth factor A (VEGFA; hereafter referred to as VEGF) is a key regulator of physiological and pathological angiogenesis. Two families of VEGF isoforms are generated by alternate splice-site selection in the terminal exon. Proxim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78def43363c23c17fcba6c6eefbf256d
https://europepmc.org/articles/PMC2613349/
https://europepmc.org/articles/PMC2613349/
Autor:
Sidney W. Whiteheart, Karen Gilio, Johan W. M. Heemskerk, Alastair W. Poole, Judith M.E.M. Cosemans, Yan Zhao, Paul Verkade, Zubair A. Karim, Jeffery D. Molkentin, Matthew T. Harper, Olga Konopatskaya, Steve P. Watson
Publikováno v:
The Journal of clinical investigation. 119(2)
Platelets are central players in atherothrombosis development in coronary artery disease. The PKC family provides important intracellular mechanisms for regulating platelet activity, and platelets express several members of this family, including the
Publikováno v:
Diabetologia. 48(3)
Insulin is known to stimulate endothelial nitric oxide synthesis, although much remains unknown about the intracellular mechanisms involved. This study aims to examine, in human endothelial cells, the specific contribution of heterotrimeric Gi protei
Autor:
Anna L. Barker, Olga Konopatskaya, Christopher R. Neal, Julie V. Macpherson, Jacqueline L. Whatmore, C. Peter Winlove, Patrick R. Unwin, Angela C. Shore
Publikováno v:
Physical Chemistry Chemical Physics (PCCP); Feb2004, Vol. 6 Issue 5, p1006-1011, 6p