Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Olga I. Kahn"'
Autor:
Max Adrian, Martin Weber, Ming-Chi Tsai, Caspar Glock, Olga I. Kahn, Lilian Phu, Tommy K. Cheung, William J. Meilandt, Christopher M. Rose, Casper C. Hoogenraad
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During stimulation, microglia undergo complex morphological changes, including loss of their characteristic ramified morphology, which is routinely used to
Externí odkaz:
https://doaj.org/article/07f1bdd5b8fc4c30814079f35fbb9f55
Autor:
Olga I. Kahn, Philipp Schätzle, Dieudonnée van de Willige, Roderick P. Tas, Feline W. Lindhout, Sybren Portegies, Lukas C. Kapitein, Casper C. Hoogenraad
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Microtubules in dendrites are characterized by mixed polarity orientation. Here, the authors show a role for adenomatous polyposis coli 2 (APC2) in regulating dendrite microtubule dynamics and dendrite development.
Externí odkaz:
https://doaj.org/article/ade6f2219360485a9d71326ab47cd9a9
Publikováno v:
Molecular Biology of the Cell
Artículos CONICYT
CONICYT Chile
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Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Inhibition of kinesin-5, a molecular motor protein best known for its essential role in mitosis, has notable effects on the morphology and microtubule organization of dendrites of terminally postmitotic neurons. Kinesin-5 acts as a brake that can lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6d66734f6c7a6673e86c8dd35d70c1
http://europepmc.org/articles/PMC4279230
http://europepmc.org/articles/PMC4279230
Autor:
Peter W. Baas, Olga I. Kahn
Navigation of the growth cone at the tip of the developing axon is crucial for the proper wiring of the nervous system. Mechanisms of actin-dependent growth cone steering, via signaling cascades, are well documented. Microtubules are also important i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b840fc27ad177cf4565a4c85a929257
https://europepmc.org/articles/PMC4930683/
https://europepmc.org/articles/PMC4930683/
Publikováno v:
Cytoskeleton (Hoboken, N.J.). 72(7)
TPX2 (targeting protein for Xklp2) is a multifunctional mitotic spindle assembly factor that in mammalian cells localizes and regulates mitotic motor protein kinesin-5 (also called Eg5 or kif11). We previously showed that upon depletion or inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::712b8bd93ffda2183a4de4eb811b3d0c
https://pubmed.ncbi.nlm.nih.gov/26257190
https://pubmed.ncbi.nlm.nih.gov/26257190
Autor:
Olga I. Kahn, Peter W. Baas
Publikováno v:
Kinesins and Cancer ISBN: 9789401797313
Detailed analyses of the behavior of cancer cells have revealed a significant deregulation of the cell cycle leading to increased proliferation rates along with often aggressive invasive properties of the affected cells. Microtubules, the first major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc0f1b0b1a221c10119b779d58f7793d
https://doi.org/10.1007/978-94-017-9732-0_14
https://doi.org/10.1007/978-94-017-9732-0_14