Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Olga I, Yarovaya"'
Autor:
Kseniya S. Kovaleva, Olga I. Yarovaya, Irina A. Chernyshova, Alexandra L. Zakharenko, Sergey V. Cheresiz, Amirhossein Azimirad, Andrey G. Pokrovsky, Olga I. Lavrik, Nariman F. Salakhutdinov
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1743 (2023)
New imidazolidine-2,4,5-triones with norabietic, nordehydroabietic, and adamantane substituents were synthesized by reacting oxalyl chloride and the corresponding ureas, providing good yields. Bioisosteric replacement of the ureide group with a parab
Externí odkaz:
https://doaj.org/article/762c351df9fd453b962ba98d14d82149
Autor:
Svetlana V. Belenkaya, Iuliia A. Merkuleva, Olga I. Yarovaya, Varvara Yu Chirkova, Elena A. Sharlaeva, Daniil V. Shanshin, Ekaterina A. Volosnikova, Sergey Z. Vatsadze, Mikhail V. Khvostov, Nariman F. Salakhutdinov, Dmitriy Shcherbakov
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/d70b4ae2479f41fb94be18a79decf063
Autor:
Svetlana V. Belenkaya, Iuliia A. Merkuleva, Olga I. Yarovaya, Varvara Yu. Chirkova, Elena A. Sharlaeva, Daniil V. Shanshin, Ekaterina A. Volosnikova, Sergey Z. Vatsadze, Mikhail V. Khvostov, Nariman F. Salakhutdinov, Dmitriy N. Shcherbakov
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Despite the long history of use and the knowledge of the genetics and biochemistry of E. coli, problems are still possible in obtaining a soluble form of recombinant proteins in this system. Although, soluble protein can be obtained both in the cytop
Externí odkaz:
https://doaj.org/article/46c0a4c44b8147dfae40d0e507f092ef
Autor:
Olga I. Yarovaya, Aleksandr S. Filimonov, Dmitriy S. Baev, Sophia S. Borisevich, Anna V. Zaykovskaya, Varvara Yu. Chirkova, Mariya K. Marenina, Yulia V. Meshkova, Svetlana V. Belenkaya, Dmitriy N. Shcherbakov, Maxim A. Gureev, Olga A. Luzina, Oleg V. Pyankov, Nariman F. Salakhutdinov, Mikhail V. Khvostov
Publikováno v:
Viruses, Vol 16, Iss 2, p 215 (2024)
Although the COVID-19 pandemic caused by SARS-CoV-2 viruses is officially over, the search for new effective agents with activity against a wide range of coronaviruses is still an important task for medical chemists and virologists. We synthesized a
Externí odkaz:
https://doaj.org/article/f8027d82e2904b38a99ec1ab28d8aae6
Autor:
Sophia S. Borisevich, Vladimir V. Zarubaev, Dmitriy N. Shcherbakov, Olga I. Yarovaya, Nariman F. Salakhutdinov
Publikováno v:
Viruses, Vol 15, Iss 4, p 902 (2023)
The fusion of viral and cell membranes is one of the basic processes in the life cycles of viruses. A number of enveloped viruses confer fusion of the viral envelope and the cell membrane using surface viral fusion proteins. Their conformational rear
Externí odkaz:
https://doaj.org/article/deeb7744a6a84baf81c6060655086afe
Autor:
Ekaterina D. Mordvinova, Polina A. Nikitina, Olga I. Yarovaya, Ekaterina A. Volosnikova, Denis E. Murashkin, Anastasiya A. Isaeva, Tatiana Y. Koldaeva, Valery P. Perevalov, Nariman F. Salakhutdinov, Dmitriy N. Shcherbakov
Publikováno v:
Chemosensors, Vol 11, Iss 2, p 135 (2023)
Angiotensin-converting enzyme 2 (ACE2), the functional receptor of SARS-CoV-2, plays a crucial role in the pathogenesis of COVID-19. ACE2 targeting holds the promise for preventing and inhibiting SARS-CoV-2 infection. In this work, we describe the de
Externí odkaz:
https://doaj.org/article/9e7c8c4cc3f945dfb9c9c74a84b1a036
Autor:
Evgenii S. Mozhaitsev, Evgeniy V. Suslov, Daria A. Rastrepaeva, Olga I. Yarovaya, Sophia S. Borisevich, Edward M. Khamitov, Dmitry S. Kolybalov, Sergey G. Arkhipov, Nikolai I. Bormotov, Larisa N. Shishkina, Olga A. Serova, Roman V. Brunilin, Andrey A. Vernigora, Maxim B. Nawrozkij, Alexander P. Agafonov, Rinat A. Maksyutov, Konstantin P. Volcho, Nariman F. Salakhutdinov
Publikováno v:
Viruses, Vol 15, Iss 1, p 29 (2022)
Despite the fact that the variola virus is considered eradicated, the search for new small molecules with activity against orthopoxviruses remains an important task, especially in the context of recent outbreaks of monkeypox. As a result of this work
Externí odkaz:
https://doaj.org/article/b922d070a1ef46cfb657380579218c15
Autor:
Dmitry S. Baev, Mikhail E. Blokhin, Varvara Yu. Chirkova, Svetlana V. Belenkaya, Olga A. Luzina, Olga I. Yarovaya, Nariman F. Salakhutdinov, Dmitry N. Shcherbakov
Publikováno v:
Molecules, Vol 28, Iss 1, p 303 (2022)
Although the incidence and mortality of SARS-CoV-2 infection has been declining during the pandemic, the problem related to designing novel antiviral drugs that could effectively resist viruses in the future remains relevant. As part of our continued
Externí odkaz:
https://doaj.org/article/d98182c6b8994f668a3e411048bbd133
Autor:
Anastasiya S. Sokolova, Olga I. Yarovaya, Lana V. Kuzminykh, Anna A. Shtro, Artem M. Klabukov, Anastasia V. Galochkina, Yulia V. Nikolaeva, Galina D. Petukhova, Sophia S. Borisevich, Edward M. Khamitov, Nariman F. Salakhutdinov
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1390 (2022)
Respiratory syncytial virus (RSV) causes acute respiratory infections, thus, posing a serious threat to the health of infants, children, and elderly people. In this study, we have discovered a series of potent RSV entry inhibitors with the (-)-borneo
Externí odkaz:
https://doaj.org/article/0f1616c0654d4805a855279093cc914a
Autor:
Aleksandr S. Filimonov, Olga I. Yarovaya, Anna V. Zaykovskaya, Nadezda B. Rudometova, Dmitriy N. Shcherbakov, Varvara Yu. Chirkova, Dmitry S. Baev, Sophia S. Borisevich, Olga A. Luzina, Oleg V. Pyankov, Rinat A. Maksyutov, Nariman F. Salakhutdinov
Publikováno v:
Viruses, Vol 14, Iss 10, p 2154 (2022)
In order to test the antiviral activity, a series of usnic acid derivatives were synthesized, including new, previously undescribed compounds. The activity of the derivatives against three strains of SARS-CoV-2 virus was studied. To understand the me
Externí odkaz:
https://doaj.org/article/76f774f4204142e9bc4b2b0c5d7f7224