Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Olga Gurevitch"'
Autor:
Elena Gaberman, William H. McBride, Lilia Levdansky, Raphael Gorodetsky, Esther Lubzens, Olga Gurevitch
Publikováno v:
Tissue Engineering Part C: Methods. 17:745-755
Efficient transfer of progenitor cells without affecting their survival is a key factor in any practical cell therapy. Fibrin microbeads (FMB) were developed as hard biodegradable cell carriers. The FMB could efficiently isolate mesenchymal stem cell
Publikováno v:
Current Stem Cell Research & Therapy. 5:49-56
We present a novel, reverse thermo-responsive (RTR) polymeric osteogenic composite comprising demineralized bone matrix (DBM) and unmanipulated bone marrow cells (BMC) for repair of bone defects. The polymers investigated were low viscosity aqueous s
Autor:
Gregory Elkin, Elena Yakovlev, Shoshana Morecki, Olga Gurevitch, Tatyana B. Prigozhina, Shimon Slavin
Publikováno v:
Experimental Hematology. 31:81-88
Objective We previously demonstrated that allogeneic bone marrow transplantation (BMT) after low-dose total lymphoid irradiation (200 cGy) and depletion of donor-reactive cells with cyclophosphamide (Cy) converted recipients to graft-vs-host disease
Autor:
Memet Aker, S. Slavin, Olga Gurevitch, Arnon Nagler, Reuven Or, T. Prighozina, M Y Shapira, S. Panighari
Publikováno v:
Bone Marrow Transplantation. 25:S54-S57
Following engraftment of donor hematopoietic cells and induction of host-versus-graft tolerance, immunocompetent lymphocytes of donor origin can induce graft-versus-leukemia (GVL) and graft-versus-tumor (GVT) effects. Engraftment of allogeneic bone m
Publikováno v:
Transplantation. 68:1362-1368
Successful engraftment of hematopoietic stem cells requires a supportive hematopoietic stromal microenvironment (HSM). Defects in the HSM associated with aplastic anemia, myelofibrosis, or caused by intensive ionizing radiation and chemotherapy gener
Publikováno v:
Annals of the New York Academy of Sciences. 862:37-44
We have recently introduced a new approach for induction of transplantation tolerance to donor alloantigens using well-tolerated non-myeloablative conditioning across MHC and xenogeneic barriers in mice. Our regimen consists of no or very low doses o
Autor:
Andras Muhlrad, Dan Gazit, Michael Chorev, M Vidson, A. Shteyer, I. Bab, E Berger, I Bleiberg, Olga Gurevitch, M Namdar-Attar, Shimon Slavin
Publikováno v:
Blood. 88:4719-4724
The osteogenic growth peptide (OGP) was characterized recently in regenerating bone marrow (BM) and normal serum. In vitro, the OGP regulates stromal-cell proliferation and differentiated functions. In vivo, an increase in serum OGP accompanies the o
Autor:
Gregory, Elkin, Tatyana B, Prigozhina, Shimon, Slavin, Olga, Gurevitch, Sofia, Khitrin, Igor B, Resnick
Publikováno v:
American journal of blood research. 1(2)
Background: Donor Lymphocyte Infusion (DLI) is a well-recognized tool for augmentation of the anti-leukemia effect after mismatched bone marrow transplantation. Experimental results show, however, that DLI efficacy is strongly dependent on the number
Publikováno v:
Medical hypotheses. 69(3)
Summary Marrow cavities in all the bones of newborn mammals contain active hematopoietic tissue, known as red bone marrow. From the early postnatal period onwards, the hematopoietic tissue, mainly in the bones of the extremities, is gradually replace
Autor:
Shimon Slavin, Olga Gurevitch
Publikováno v:
Medical hypotheses. 67(4)
Summary In this article we present a new working hypothesis, suggesting that overexertion of the hematopoietic system resulting from constant excessive need for blood cell production, plays an important role in the etiology of osteoporosis. It is gen