Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Olga Gonzalez"'
Autor:
In-Jeong Kim, Olga Gonzalez, Michael P. Tighe, Paula A. Lanthier, Madeline J. Clark, Kelsey L. Travis, Timothy C. Low-Beer, Kathleen G. Lanzer, Derek T. Bernacki, Frank M. Szaba, Rafael A. De La Barrera, Vincent Dussupt, Letzibeth Mendez-Rivera, Shelly J. Krebs, Corinna N. Ross, Stephanie D. Mdaki, Kathleen M. Brasky, Donna Layne-Colon, Suzette D. Tardif, Stephen J. Thomas, Kayvon Modjarrad, Marcia A. Blackman, Jean L. Patterson
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Zika virus (ZIKV) infection during pregnancy poses significant threats to maternal and fetal health, leading to intrauterine fetal demise and severe developmental malformations that constitute congenital Zika syndrome (CZS). As such, the dev
Externí odkaz:
https://doaj.org/article/b9add105d8704c0d82513d7770efca3f
Autor:
In-Jeong Kim, Paula A. Lanthier, Madeline J. Clark, Rafael A. De La Barrera, Michael P. Tighe, Frank M. Szaba, Kelsey L. Travis, Timothy C. Low-Beer, Tres S. Cookenham, Kathleen G. Lanzer, Derek T. Bernacki, Lawrence L. Johnson, Amanda A. Schneck, Corinna N. Ross, Suzette D. Tardif, Donna Layne-Colon, Stephanie D. Mdaki, Edward J. Dick, Colin Chuba, Olga Gonzalez, Kathleen M. Brasky, John Dutton, Julienne N. Rutherford, Lark L. Coffey, Anil Singapuri, Claudia Sanchez San Martin, Charles Y. Chiu, Stephen J. Thomas, Kayvon Modjarrad, Jean L. Patterson, Marcia A. Blackman
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Zika virus (ZIKV) is a mosquito-borne arbovirus that can cause severe congenital birth defects. The utmost goal of ZIKV vaccines is to prevent both maternal-fetal infection and congenital Zika syndrome. A Zika purified inactivated virus (ZPI
Externí odkaz:
https://doaj.org/article/83cd979680154fe68132d19796feb226
Autor:
Bindu Singh, Chivonne Moodley, Dhiraj K. Singh, Ruby A. Escobedo, Riti Sharan, Garima Arora, Shashank R. Ganatra, Vinay Shivanna, Olga Gonzalez, Shannan Hall-Ursone, Edward J. Dick Jr., Deepak Kaushal, Xavier Alvarez, Smriti Mehra
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
The expression of indoleamine 2,3-dioxygenase (IDO), a robust immunosuppressant, is significantly induced in macaque tuberculosis (TB) granulomas, where it is expressed on IFN-responsive macrophages and myeloid-derived suppressor cells. IDO expressio
Externí odkaz:
https://doaj.org/article/59e3a53626764aa2a1294a8cc4c559ab
Autor:
Riti Sharan, Shashank R. Ganatra, Dhiraj K. Singh, Journey Cole, Taylor W. Foreman, Rajesh Thippeshappa, Charles A. Peloquin, Vinay Shivanna, Olga Gonzalez, Cheryl L. Day, Neel R. Gandhi, Edward J. Dick Jr., Shannan Hall-Ursone, Smriti Mehra, Larry S. Schlesinger, Jyothi Rengarajan, Deepak Kaushal
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 18 (2022)
A once-weekly oral dose of isoniazid and rifapentine for 3 months (3HP) is recommended by the CDC for treatment of latent tuberculosis infection (LTBI). The aim of this study is to assess 3HP-mediated clearance of M. tuberculosis bacteria in macaques
Externí odkaz:
https://doaj.org/article/659732e8266a421b8e6775d23db444b0
Autor:
Julia M. Scordo, Tucker J. Piergallini, Nicole Reuter, Colwyn A. Headley, Vida L. Hodara, Olga Gonzalez, Luis D. Giavedoni, James F. Papin, Joanne Turner
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-9 (2021)
Abstract Individuals over the age of 65 are highly susceptible to infectious diseases, which account for one-third of deaths in this age group. Vaccines are a primary tool to combat infection, yet they are less effective in the elderly population. Wh
Externí odkaz:
https://doaj.org/article/e28f5e23166a46f888ca29c81760a216
Autor:
Mareike C. Janiak, Michael J. Montague, Catalina I. Villamil, Michala K. Stock, Amber E. Trujillo, Allegra N. DePasquale, Joseph D. Orkin, Samuel E. Bauman Surratt, Olga Gonzalez, Michael L. Platt, Melween I. Martínez, Susan C. Antón, Maria Gloria Dominguez-Bello, Amanda D. Melin, James P. Higham
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Background An individual’s microbiome changes over the course of its lifetime, especially during infancy, and again in old age. Confounding factors such as diet and healthcare make it difficult to disentangle the interactions between age,
Externí odkaz:
https://doaj.org/article/4fe39fc5c7a14c58b99b21353d599499
Autor:
Bruce A. Rosa, Mushtaq Ahmed, Dhiraj K. Singh, José Alberto Choreño-Parra, Journey Cole, Luis Armando Jiménez-Álvarez, Tatiana Sofía Rodríguez-Reyna, Bindu Singh, Olga Gonzalez, Ricardo Carrion, Larry S. Schlesinger, John Martin, Joaquín Zúñiga, Makedonka Mitreva, Deepak Kaushal, Shabaana A. Khader
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Rosa et al. find that genes associated with Interferon (IFN) signaling, neutrophil degranulation and innate immune pathways are induced in the lungs of macaques in response to SARS-CoV-2 infection, whereas genes associated with collagen formation and
Externí odkaz:
https://doaj.org/article/fee1d848484c4499aa50fa45ecb7d32f
Autor:
Fatai S. Oladunni, Jun-Gyu Park, Paula A. Pino, Olga Gonzalez, Anwari Akhter, Anna Allué-Guardia, Angélica Olmo-Fontánez, Shalini Gautam, Andreu Garcia-Vilanova, Chengjin Ye, Kevin Chiem, Colwyn Headley, Varun Dwivedi, Laura M. Parodi, Kendra J. Alfson, Hilary M. Staples, Alyssa Schami, Juan I. Garcia, Alison Whigham, Roy Neal Platt, Michal Gazi, Jesse Martinez, Colin Chuba, Stephanie Earley, Oscar H. Rodriguez, Stephanie Davis Mdaki, Katrina N. Kavelish, Renee Escalona, Cory R. A. Hallam, Corbett Christie, Jean L. Patterson, Tim J. C. Anderson, Ricardo Carrion, Edward J. Dick, Shannan Hall-Ursone, Larry S. Schlesinger, Xavier Alvarez, Deepak Kaushal, Luis D. Giavedoni, Joanne Turner, Luis Martinez-Sobrido, Jordi B. Torrelles
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Here, the authors characterize tissue-level SARS-CoV-2 infection and pathogenesis in transgenic mice expressing human angiotensin converting enzyme 2 (hACE2) by the human cytokeratin 18 promoter (K18-hACE2) and show that infection induces lethality,
Externí odkaz:
https://doaj.org/article/36d6d32972464a4aafa1c9bc19844493
Autor:
Yuliaxis Ramayo-Caldas, Francesc Prenafeta-Boldú, Laura M. Zingaretti, Olga Gonzalez-Rodriguez, Antoni Dalmau, Raquel Quintanilla, Maria Ballester
Publikováno v:
Animal Microbiome, Vol 2, Iss 1, Pp 1-12 (2020)
Abstract Background The pig gut microbiome harbors thousands of species of archaea, bacteria, viruses and eukaryotes such as protists and fungi. However, since the majority of published studies have been focused on prokaryotes, little is known about
Externí odkaz:
https://doaj.org/article/d6a7b498506b41389ebd9c8921babacb
Autor:
In-Jeong Kim, Paula A. Lanthier, Madeline J. Clark, Rafael A. De La Barrera, Michael P. Tighe, Frank M. Szaba, Kelsey L. Travis, Timothy C. Low-Beer, Tres S. Cookenham, Kathleen G. Lanzer, Derek T. Bernacki, Lawrence L. Johnson, Amanda A. Schneck, Corinna N. Ross, Suzette D. Tardif, Donna Layne-Colon, Stephanie D. Mdaki, Edward J. Dick, Colin Chuba, Olga Gonzalez, Kathleen M. Brasky, John Dutton, Julienne N. Rutherford, Lark L. Coffey, Anil Singapuri, Claudia Sanchez San Martin, Charles Y. Chiu, Stephen J. Thomas, Kayvon Modjarrad, Jean L. Patterson, Marcia A. Blackman
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/04deac723e8743229172549357052591