Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Olga Gewartowska"'
Autor:
Małgorzata Rydzanicz, Bozena Kuzniewska, Marta Magnowska, Tomasz Wójtowicz, Aleksandra Stawikowska, Anna Hojka, Ewa Borsuk, Ksenia Meyza, Olga Gewartowska, Jakub Gruchota, Jacek Miłek, Patrycja Wardaszka, Izabela Chojnicka, Ludwika Kondrakiewicz, Dorota Dymkowska, Alicja Puścian, Ewelina Knapska, Andrzej Dziembowski, Rafał Płoski, Magdalena Dziembowska
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 11, Pp 2976-3004 (2024)
Abstract There is increasing evidence of mitochondrial dysfunction in autism spectrum disorders (ASD), but the causal relationships are unclear. In an ASD patient whose identical twin was unaffected, we identified a postzygotic mosaic mutation p.Q639
Externí odkaz:
https://doaj.org/article/1143eedef2364432b4464c62a2067b71
Autor:
Michał Brouze, Agnieszka Czarnocka-Cieciura, Olga Gewartowska, Monika Kusio-Kobiałka, Kamil Jachacy, Marcin Szpila, Bartosz Tarkowski, Jakub Gruchota, Paweł Krawczyk, Seweryn Mroczek, Ewa Borsuk, Andrzej Dziembowski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Cytoplasmic polyadenylation plays a vital role in gametogenesis; however, the participating enzymes and substrates in mammals remain unclear. Using knockout and knock-in mouse models, we describe the essential role of four TENT5 poly(A) poly
Externí odkaz:
https://doaj.org/article/8da351a5408d442a850de28038fde70e
Autor:
Bozena Kuzniewska, Karolina Rejmak, Agata Nowacka, Magdalena Ziółkowska, Jacek Milek, Marta Magnowska, Jakub Gruchota, Olga Gewartowska, Ewa Borsuk, Ahmad Salamian, Andrzej Dziembowski, Kasia Radwanska, Magdalena Dziembowska
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
As microRNAs have emerged to be important regulators of molecular events occurring at the synapses, the new questions about their regulatory effect on the behavior have araised. In the present study, we show for the first time that the dysregulated s
Externí odkaz:
https://doaj.org/article/ce05333691984f1d9415951ca513f808
Autor:
Aleksandra Bilska, Monika Kusio-Kobiałka, Paweł S. Krawczyk, Olga Gewartowska, Bartosz Tarkowski, Kamil Kobyłecki, Dominika Nowis, Jakub Golab, Jakub Gruchota, Ewa Borsuk, Andrzej Dziembowski, Seweryn Mroczek
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Regulating polyadenylation is important for mRNA stability, which can in turn affect B cell maturation and humoral immune responses. Here the authors use Nanopore poly(A) sequencing to explore the importance of the cytoplasmic poly(A) polymerase TENT
Externí odkaz:
https://doaj.org/article/cc7369751a0649a8ac0d65c96e3806d5
Autor:
Olga Gewartowska, Goretti Aranaz-Novaliches, Paweł S. Krawczyk, Seweryn Mroczek, Monika Kusio-Kobiałka, Bartosz Tarkowski, Frantisek Spoutil, Oldrich Benada, Olga Kofroňová, Piotr Szwedziak, Dominik Cysewski, Jakub Gruchota, Marcin Szpila, Aleksander Chlebowski, Radislav Sedlacek, Jan Prochazka, Andrzej Dziembowski
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109015- (2021)
Summary: Osteoblasts orchestrate bone formation through the secretion of type I collagen and other constituents of the matrix on which hydroxyapatite crystals mineralize. Here, we show that TENT5A, whose mutations were found in congenital bone diseas
Externí odkaz:
https://doaj.org/article/72264ef180444effa54deb1100b552fa
Autor:
Olga Gewartowska, Seweryn Mroczek, Goretti Aranaz Novaliches, Monika Kusio-Kobiałka, Jan Prochazka, Andrzej Dziembowski
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100344- (2020)
Externí odkaz:
https://doaj.org/article/068a149ed5904d3291f585e6999a1cf7
Autor:
Korneliusz Kurek, Olga Gewartowska, Katarzyna Tołkacz, Bogumiła Jędrzejewska, Robert W Mysłajek
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0237243 (2020)
Our understanding of animal adaptations to human pressure is limited by the focus on rare taxa, despite that common species are more significant in shaping structure, function and service provision of ecosystems. Thus better understanding of their ec
Externí odkaz:
https://doaj.org/article/1469426f3edc46c091e17a90c1060581
Autor:
Seweryn Mroczek, Justyna Chlebowska, Tomasz M. Kuliński, Olga Gewartowska, Jakub Gruchota, Dominik Cysewski, Vladyslava Liudkovska, Ewa Borsuk, Dominika Nowis, Andrzej Dziembowski
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
FAM46C is one of the most frequently mutated genes in multiple myeloma (MM), but its molecular function remains unknown. Here the authors show that FAM46C is a poly(A) polymerase and that loss of function of FAM46C drives multiple myeloma through the
Externí odkaz:
https://doaj.org/article/2729a3c633ac4d3d9be13d21bf41dfa0
Autor:
Paweł S Krawczyk, Olga Gewartowska, Michał Mazur, Wiktoria Orzeł, Katarzyna Matylla-Kulińska, Sebastian Jeleń, Paweł Turowski, Tomasz Śpiewla, Bartosz Tarkowski, Agnieszka Tudek, Aleksandra Brouze, Aleksandra Wesołowska, Dominika Nowis, Jakub Gołąb, Joanna Kowalska, Jacek Jemielity, Andrzej Dziembowski, Seweryn Mroczek
Though mRNA vaccines against COVID-19 have revolutionized vaccinology and have been administered in billions of doses, we know incredibly little about how mRNA vaccines are metabolizedin vivo. Here we implemented enhanced nanopore Direct RNA sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5433e62b4ff352e3cb1129694b9a9339
https://doi.org/10.1101/2022.12.01.518149
https://doi.org/10.1101/2022.12.01.518149
Autor:
Aleksander Chlebowski, Goretti Aranaz-Novaliches, Olga Kofroňová, Oldrich Benada, Andrzej Dziembowski, Monika Kusio-Kobiałka, Dominik Cysewski, Radislav Sedlacek, Jan Prochazka, Bartosz Tarkowski, Olga Gewartowska, Pawel S. Krawczyk, Marcin Szpila, Piotr Szwedziak, Frantisek Spoutil, Jakub Gruchota, Seweryn Mroczek
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109015-(2021)
Summary: Osteoblasts orchestrate bone formation through the secretion of type I collagen and other constituents of the matrix on which hydroxyapatite crystals mineralize. Here, we show that TENT5A, whose mutations were found in congenital bone diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c983c65089ca337e2406ded83222fe9
http://www.sciencedirect.com/science/article/pii/S2211124721003296
http://www.sciencedirect.com/science/article/pii/S2211124721003296