Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Olga G Ovchinnikova"'
Autor:
Taylor J. B. Forrester, Olga G. Ovchinnikova, Zhixiong Li, Elena N. Kitova, Jeremy T. Nothof, Akihiko Koizumi, John S. Klassen, Todd L. Lowary, Chris Whitfield, Matthew S. Kimber
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
WbbB is a structurally unusual retaining glycosyltransferase. Here, the authors show that WbbB forms an Asp232-Kdo adduct prior to transfer to the saccharide acceptor. Therefore, unlike any previously studied glycosyltransferase, WbbB uses the double
Externí odkaz:
https://doaj.org/article/2fa33b5bdb8243bf8c1fb3e07ccfe81c
Autor:
Olga G. Ovchinnikova, Logan P. Treat, Tanisha Teelucksingh, Bradley R. Clarke, Taryn A. Miner, Chris Whitfield, Kimberly A. Walker, Virginia L. Miller
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Klebsiella pneumoniae is a leading cause of nosocomial infections, including pneumonia, bacteremia, and urinary tract infections. Treatment options are increasingly restricted by the high prevalence of resistance to frontline antibiotics, in
Externí odkaz:
https://doaj.org/article/8357e1b51d36462e839941a564b8e951
Autor:
Taylor J. B. Forrester, Olga G. Ovchinnikova, Zhixiong Li, Elena N. Kitova, Jeremy T. Nothof, Akihiko Koizumi, John S. Klassen, Todd L. Lowary, Chris Whitfield, Matthew S. Kimber
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/70513d97c9e147d892c0109832b3dc52
Autor:
Lindsey A. Carfrae, Kenneth Rachwalski, Shawn French, Rodion Gordzevich, Laura Seidel, Caressa N. Tsai, Megan M. Tu, Craig R. MacNair, Olga G. Ovchinnikova, Bradley R. Clarke, Chris Whitfield, Eric D. Brown
Publikováno v:
Nature Microbiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81d6b82e52a7bb6a76e755becb078789
https://doi.org/10.1038/s41564-023-01369-z
https://doi.org/10.1038/s41564-023-01369-z
Autor:
Liam Doyle, Olga G. Ovchinnikova, Bo-Shun Huang, Taylor J.B. Forrester, Todd L. Lowary, Matthew S. Kimber, Chris Whitfield
Publikováno v:
Journal of Biological Chemistry. 299:104609
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5581f8b0ef6fe24f270eae0dc5b964a
https://doi.org/10.1016/j.jbc.2023.104609
https://doi.org/10.1016/j.jbc.2023.104609
Autor:
Evgeniya A. Levina, Yuriy A. Knirel, Olga G. Ovchinnikova, Małgorzata Siwińska, Alexander S. Shashkov, Agnieszka Zabłotni, Antoni Rozalski
Publikováno v:
International Journal of Biological Macromolecules. 163:1168-1174
The serological classification scheme of the opportunistic Proteus bacilli includes a number of Proteus penneri strains. The tested P. penneri 4034-85 strain turned out to be serologically distinguished in ELISA and Western blotting. The O-polysaccha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5139e538c35b22a7fa06c536814784b9
https://doi.org/10.1016/j.ijbiomac.2020.07.012
https://doi.org/10.1016/j.ijbiomac.2020.07.012
Autor:
Russel Gitalis, Evan Mallette, Matthew S. Kimber, Bradley R. Clarke, Chris Whitfield, Todd L. Lowary, Evelyn R Kamski-Hennekam, Ryan P. Sweeney, Steven D. Kelly, Olga G Ovchinnikova
Publikováno v:
Nature Chemical Biology. 16:450-457
Lipopolysaccharide O-antigen is an attractive candidate for immunotherapeutic strategies targeting antibiotic-resistant Klebsiella pneumoniae. Several K. pneumoniae O-serotypes are based on a shared O2a-antigen backbone repeating unit: (→ 3)-α-Gal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238275291aaea514b07513ecd6af77f1
https://doi.org/10.1038/s41589-020-0494-0
https://doi.org/10.1038/s41589-020-0494-0
Autor:
Chris Whitfield, M. Sameer Al-Abdul-Wahid, Steven D. Kelly, Olga G Ovchinnikova, Bradley R. Clarke, Bin Liu, Evan Mann
Publikováno v:
Journal of Biological Chemistry. 294:14978-14990
Escherichia coli serotype O9a provides a model for export of lipopolysaccharide (LPS) O-antigen polysaccharide (O-PS) via ABC transporters. In O9a biosynthesis, a chain-terminator enzyme, WbdD, caps the nonreducing end of the glycan with a methylphos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6277ed3ddff167a8dbb2207c1e2ab3e2
https://doi.org/10.1074/jbc.ra119.010323
https://doi.org/10.1074/jbc.ra119.010323
Autor:
Todd L. Lowary, Bo-Shun Huang, Chris Whitfield, Olga G Ovchinnikova, David E. Williams, Stephen G. Withers, Zhizeng Gao, Raymond J. Andersen, Feng Liu
Publikováno v:
Journal of the American Chemical Society. 141:2201-2204
Bacterial capsular polysaccharides are important virulence factors. Capsular polysaccharides from several important Gram-negative pathogens share a conserved glycolipid terminus containing 3-deoxy-β-d- manno-oct-2-ulosonic acid (β-Kdo). The β-Kdo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6606e5107c7678c067d885b7fcf625d2
https://doi.org/10.1021/jacs.8b10940
https://doi.org/10.1021/jacs.8b10940
Publikováno v:
The Journal of Biological Chemistry
Salmonella enterica serovar Typhi causes typhoid fever. It possesses a Vi antigen capsular polysaccharide coat that is important for virulence and is the basis of a current glycoconjugate vaccine. Vi antigen is also produced by environmental Bordetel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483b7076ca7193a91000f11dd1c6f20a
https://doi.org/10.1016/j.jbc.2021.101486
https://doi.org/10.1016/j.jbc.2021.101486