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pro vyhledávání: '"Olga Fuchs"'
Publikováno v:
ChemBioChem. 17:1207-1210
Thiamine diphosphate-dependent enzymes catalyze the formation of C-C bonds, thereby generating chiral secondary or tertiary alcohols. By the use of vibrational circular dichroism (VCD) spectroscopy we studied the stereoselectivity of carboligations c
Autor:
Felix Kratz, Friederike I. Nollmann, Olga Fuchs, Koester Stephan David, Simon Waltzer, André Warnecke, Khalid Abu Ajaj
Publikováno v:
Cancer Research. 76:4858-4858
Drug delivery systems in oncology for treating cancer are based on different drug release mechanisms at the tumor site including primarily hydrolytic, reductive, enzymatic and/or acid-sensitive cleavage. Drug carrier conjugates that incorporate an ac
Publikováno v:
Cancer Research. 76:2061-2061
Gemcitabine (Gemzar®) is an anticancer nucleoside that is widely used to treat solid tumors. Unfortunately, at its recommended dose of ∼1000 mg/m2 approximately 90% are deactivated by cytidine deaminase to the inactive uridine metabolite and excre