Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Olga Eguaogie"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 955-970 (2018)
The application of mechanical force to induce the formation and cleavage of covalent bonds is a rapidly developing field within organic chemistry which has particular value in reducing or eliminating solvent usage, enhancing reaction rates and also i
Externí odkaz:
https://doaj.org/article/93cc5497f3f84666af792fd535f137c6
Autor:
Olga Eguaogie, Patrick F. Conlon, Francesco Ravalico, Jamie S. T. Sweet, Thomas B. Elder, Louis P. Conway, Marc E. Lennon, David R. W. Hodgson, Joseph S. Vyle
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 87-92 (2017)
Vibration ball-milling in a zirconia-lined vessel afforded clean and quantitative nucleophilic displacement reactions between 4-methoxybenzylthiolate salts and nucleoside 5′-halides or 5′-tosylates in five to 60 minutes. Under these conditions, c
Externí odkaz:
https://doaj.org/article/6d3b6b6007ef41de80e4fea654d64978
Publikováno v:
Beilstein Journal of Organic Chemistry
Eguaogie, O, Vyle, J S, Conlon, P F, Gîlea, M A & Liang, Y 2018, ' Mechanochemistry of nucleosides, nucleotides and related materials ', Beilstein Journal of Organic Chemistry, vol. 14, pp. 955-970 . https://doi.org/10.3762/bjoc.14.81
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 955-970 (2018)
Eguaogie, O, Vyle, J S, Conlon, P F, Gîlea, M A & Liang, Y 2018, ' Mechanochemistry of nucleosides, nucleotides and related materials ', Beilstein Journal of Organic Chemistry, vol. 14, pp. 955-970 . https://doi.org/10.3762/bjoc.14.81
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 955-970 (2018)
The application of mechanical force to induce the formation and cleavage of covalent bonds is a rapidly developing field within organic chemistry which has particular value in reducing or eliminating solvent usage, enhancing reaction rates and also i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76737e35b98f77fc76e8300598f23f3d
http://europepmc.org/articles/PMC5942386
http://europepmc.org/articles/PMC5942386
Autor:
Julian Steinhoegl, Olga Eguaogie, Patrick F. Conlon, Christopher J. Law, Jamie S. T. Sweet, Sarah Allman, Jordan J. Wilson, Oliver G. A. Hancox, James H. R. Tucker, Klaudia Englert, Joseph S. Vyle, James P. Hall
Publikováno v:
Conlon, P, Eguaogie, O, Wilson, J, Sweet, J, Steinhoegl, J, Englert, K, Hancox, O, Law, C, Allman, S, Tucker, J H R, Hall, J & Vyle, J 2019, ' Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: a backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography ', Chemical Science, vol. 10, pp. 10948-10957 . https://doi.org/10.1039/C9SC04098F
Oligodeoxynucleotides incorporating internucleotide phosphoroselenolate linkages have been prepared under solid-phase synthesis conditions using dimer phosphoramidites. These dimers were constructed following the high yielding Michaelis-Arbuzov (M-A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bf37a04d1a39a1ef5481f8b8c7ad79
https://centaur.reading.ac.uk/86671/9/c9sc04098f.pdf
https://centaur.reading.ac.uk/86671/9/c9sc04098f.pdf
Autor:
Olga Eguaogie, Joseph S. Vyle, Angus Dwyer, P. Alain Elliott, Iris A. Bermejo, Andrew J. Cummings, James Mack, Kegan I. S. McColgan-Bannon, Francesco Ravalico, Amanda B. Maginty, Matthew R. Shannon
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 34:361-370
Novel nucleoside analogues containing photoswitchable moieties were prepared using 'click' cycloaddition reactions between 5'-azido-5'-deoxythymidine and mono- or bis-N-propargylamide-substituted azobenzenes. In solution, high to quantitative yields
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f451d25624c48c8b2544bab87eb51b
https://doi.org/10.1080/15257770.2014.1001855
https://doi.org/10.1080/15257770.2014.1001855
Autor:
Olga Eguaogie, Joseph S. Vyle
Publikováno v:
Eguaogie, O & Vyle, J S 2018, ' Vibration Ball Milling for the Synthesis of 5'-Thioadenosine 5'-Pyrophosphate (P'→5') Adenosine (dASppA) ', Current protocols in nucleic acid chemistry, vol. 70, pp. 1.41.1-1.41.12 . https://doi.org/10.1002/cpnc.37
Current Protocols in Nucleic Acid Chemistry
Current Protocols in Nucleic Acid Chemistry
Using vibration ball milling, 5'-chloro-5'-deoxyadenosine (CldA) reacts cleanly with 4-methoxybenzyl mercaptan (MobSH), under basic conditions, to the corresponding thioether (MobSdA), which is isolated following precipitation and trituration. Under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295d03d562aafe76070b739aeb938698
https://pubmed.ncbi.nlm.nih.gov/28921493
https://pubmed.ncbi.nlm.nih.gov/28921493
Autor:
Francesco Ravalico, Louis P. Conway, Thomas B Elder, Olga Eguaogie, Patrick F. Conlon, Marc E Lennon, Joseph S. Vyle, David R. W. Hodgson, Jamie S. T. Sweet
Publikováno v:
Eguaogie, O, Conlon, P F, Ravalico, F, Sweet, J, Elder, T B, Conway, L P, Lennon, M E, Hodgson, D R W & Vyle, J S 2017, ' Nucleophilic displacement reactions of 5′-derivatised nucleosides in a vibration ball mill ', Beilstein Journal of Organic Chemistry, vol. 13, pp. 87–92 . https://doi.org/10.3762/bjoc.13.11
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 87-92 (2017)
Beilstein journal of organic chemistry, 2017, Vol.13, pp.87-92 [Peer Reviewed Journal]
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 87-92 (2017)
Beilstein journal of organic chemistry, 2017, Vol.13, pp.87-92 [Peer Reviewed Journal]
Beilstein Journal of Organic Chemistry
Vibration ball-milling in a zirconia-lined vessel afforded clean and quantitative nucleophilic displacement reactions between 4-methoxybenzylthiolate salts and nucleoside 5′-halides or 5′-tosylates in five to 60 minutes. Under these conditions, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb1bb03b796a19008183f9bccbd3023
https://pure.qub.ac.uk/en/publications/nucleophilic-displacement-reactions-of-5derivatised-nucleosides-in-a-vibration-ball-mill(81800f5a-ee28-4c8e-a011-d06f6cb2b4c0).html
https://pure.qub.ac.uk/en/publications/nucleophilic-displacement-reactions-of-5derivatised-nucleosides-in-a-vibration-ball-mill(81800f5a-ee28-4c8e-a011-d06f6cb2b4c0).html
Publikováno v:
Eguaogie, O, Conlon, P F & Vyle, J S 2016, ' Synthesis of nucleoside phosphoroselenolates via the efficient Michaelis-Arbuzov reaction of selenocyanates ', Tetrahedron Letters, vol. 57, no. 45, pp. 5000-5002 . https://doi.org/10.1016/j.tetlet.2016.09.096
The Michaelis–Arbuzov reactions of benzylselenocyanate and 5′-deoxythymidine-5′-selenocyanate with thymidine H -phosphonate proceeded rapidly in the presence of a neutral silylating agent and 2,6-lutidine to give the corresponding Se-alkyl phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d22b3ac907400481a037f6a2edad5f2
https://pure.qub.ac.uk/en/publications/synthesis-of-nucleoside-phosphoroselenolates-via-the-efficient-michaelisarbuzov-reaction-of-selenocyanates(9fdc27ce-afc9-47e8-82da-c2e0d5e08c2e).html
https://pure.qub.ac.uk/en/publications/synthesis-of-nucleoside-phosphoroselenolates-via-the-efficient-michaelisarbuzov-reaction-of-selenocyanates(9fdc27ce-afc9-47e8-82da-c2e0d5e08c2e).html
Autor:
Francesco Ravalico, Olga Eguaogie, Christopher J. Law, Patricia M. L. Martin, David R. W. Hodgson, Louis P. Conway, Leonie A. Cooke, Joseph S. Vyle
Publikováno v:
Eguaogie, O, Cooke, L, Martin, P M L, Ravalico, F, Conway, L P, Hodgson, D R W, Law, C J & Vyle, J S 2016, ' Synthesis of novel pyrophosphorothiolate-linked dinucleoside cap analogues in a ball mill ', Organic and Biomolecular Chemistry, vol. 14, no. 4, pp. 1201–1205 . https://doi.org/10.1039/C5OB02061A
ResearcherID
Organic and biomolecular chemistry, 2016, Vol.14(4), pp.1201-1205 [Peer Reviewed Journal]
ResearcherID
Organic and biomolecular chemistry, 2016, Vol.14(4), pp.1201-1205 [Peer Reviewed Journal]
Michaelis–Arbuzov reactions of S-aryl disulfide derivatives of 3′-thiothymidine or 5′-thioadenosine with tris(trimethylsilyl) phosphite proceeded in high yields to the corresponding phosphorothiolate monoesters. Subsequent hydrolytic desilylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9bd784888632395c984227b7008b2b
https://pure.qub.ac.uk/en/publications/synthesis-of-novel-pyrophosphorothiolatelinked-dinucleoside-cap-analogues-in-a-ball-mill(b177e1fb-4489-4f99-91db-d0af7e959dd2).html
https://pure.qub.ac.uk/en/publications/synthesis-of-novel-pyrophosphorothiolatelinked-dinucleoside-cap-analogues-in-a-ball-mill(b177e1fb-4489-4f99-91db-d0af7e959dd2).html