Výsledky vyhledávání - "Olga Diakoumakou"

Akademický článek

CYP3A5 genotyping for assessing the efficacy of treatment with simvastatin and atorvastatin

Autor: Genovefa Kolovou, Vana Kolovou, Georgia Ragia, Constantinos Mihas, Olga Diakoumakou, Ioannis Vasiliadis, Sophie Mavrogeni, Vassiliki Vartela, Vangelis G Manolopoulos

Publikováno v: Genetics and Molecular Biology, Vol 38, Iss 2, Pp 129-137 (2015)

In this work, we examined the impact of polymorphism in the cytochrome P450 (CYP) 3A5 gene, CYP3A5*1 (6986A > G, rs 776746), on the reduction in the lipid levels caused by simvastatin and atorvastatin. We studied 350 hyperlipidemic patients who recei

Externí odkaz: https://doaj.org/article/7d16b70bdb294bb58276486f50e5c01c

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Microsomal triglyceride transfer protein inhibitor (lomitapide) efficacy in the treatment of patients with homozygous familial hypercholesterolaemia

Autor: Georgios Hatzigeorgiou, Evangelos Liberopoulos, Irene Mastorakou, Fedra Matsouka, Genovefa Kolovou, Theodoros Katsikas, Alexandros Tsoutsinos, Evangelos A. Zacharis, Epameinondas Fountas, Olga Diakoumakou, Stavros Stratakis, Sophie Mavrogeni, Vana Kolovou

Publikováno v: European Journal of Preventive Cardiology. 27:157-165

AimsThe aim of this study was to evaluate the effect of microsomal triglyceride transfer protein inhibitor (lomitapide) in patients with homozygous familial hypercholesterolaemia.Methods and resultsIn 12 homozygous familial hypercholesterolaemia pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4ceda85550e2fa5f8e92c53fb8128f
https://doi.org/10.1177/2047487319870007

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Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study

Autor: Smaragdi Antonopoulou, Athanasia K Papazafiropoulou, Olga Diakoumakou, Vana Kolovou, Niki Katsiki, Ioannis Vasiliadis, E. Fragopoulou, Dimitris Degiannis, Genovefa Kolovou, Leonidas H. Duntas

Publikováno v: The Open Cardiovascular Medicine Journal

Background: The influence of biomarkers in human lifespan has been investigated but with no clear results yet. Materials and methods: Lipids, Uric Acid (UA), Adiponectin (ADIPOQ), Insulin-like Growth Factor (IGF-1), cholesteryl ester transfer protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415badea5cc3da359391c4f4fc100fd3
http://europepmc.org/articles/PMC6080062

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P5365Microsomal triglyceride transfer protein inhibitor (lomitapide) efficacy in the treatment of patients with homozygous familial hypercholesterolemia phenotype

Autor: Sophie Mavrogeni, Olga Diakoumakou, F Matsouka, G Hatzigeorgiou, V Kolovou, S Stratakis, Evagelos N. Liberopoulos, I Mastorakou, Genovefa Kolovou, Evangelos A. Zacharis, A Tsoutsinos, T Katsikas, E Fountas

Publikováno v: European Heart Journal. 40

Introduction The majority of patients with homozygous familial hypercholesterolemia (HoFH) phenotype are treated additionally to lipid lowering (LL) drugs (statin + ezetimibe ± colesevelam) with lipoprotein apheresis (LA) sessions. The aim of this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::420b2c7a68c84ec04a47ec3b80ca2e3e
https://doi.org/10.1093/eurheartj/ehz746.0330

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Common Variants of Apolipoprotein E and Cholesteryl Ester Transport Protein Genes in Male Patients With Coronary Heart Disease and Variable Body Mass Index

Autor: Olga Diakoumakou, Genovefa Kolovou, Ioannis Vasiliadis, Vana Kolovou, Demosthenes B. Panagiotakos, Niki Katsiki, Sophie Mavrogeni, Vasiliki Giannakopoulou

Publikováno v: Angiology. 66:169-173

Plasma lipids are major risk factors for coronary heart disease (CHD). Cholesteryl ester transfer protein (CETP) and apolipoprotein (apo) E genes are involved in lipoprotein metabolism, thus affecting plasma lipid and lipoproteins levels. Furthermore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3652fdaf89543b0040275a7e8140a118
https://doi.org/10.1177/0003319713517927

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Cholesteryl Ester Transfer Protein Gene Polymorphisms and Longevity Syndrome

Autor: Genovefa Kolovou, Dimitri P. Mikhailidis, M Stamatelatou, Olga Diakoumakou, Katherine K. Anagnostopoulou, Peggy M. Kostakou, Constantinos Mihas, Ioannis Vasiliadis, Vana Kolovou, Dennis V. Cokkinos

Publikováno v: The Open Cardiovascular Medicine Journal

Purpose:High levels of high density lipoprotein (HDL) cholesterol are associated with a decreased risk of coronary heart disease (CHD). Subjects with high levels of HDL cholesterol (>70 mg/dl; 1.79 mmol/l) as well as high levels of low density lipopr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f509f16de2bed6668ed093b0c93c7e59
https://doi.org/10.2174/1874192401004010014

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CYP3A5 genotyping for assessing the efficacy of treatment with simvastatin and atorvastatin

Autor: Olga Diakoumakou, Vangelis G. Manolopoulos, Vana Kolovou, Vassiliki Vartela, Ioannis Vasiliadis, Georgia Ragia, Constantinos Mihas, Genovefa Kolovou, Sophie Mavrogeni

Publikováno v: Genetics and Molecular Biology v.38 n.2 2015
Genetics and Molecular Biology
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Vol 38, Iss 2, Pp 129-137 (2015)
Genetics and Molecular Biology, Volume: 38, Issue: 2, Pages: 129-137, Published: JUN 2015

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac861d3a2f07dd4ece2df7653dd9a38a
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000200129

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Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings

Autor: Genovefa Kolovou, Vana Kolovou, Maria Boutsikou, Georgios Hatzigeorgiou, Vassiliki Giannakopoulou, Sophie Mavrogeni, Nikos Gontoras, Olga Diakoumakou

Publikováno v: Cholesterol
Cholesterol, Vol 2014 (2014)

Hypertriglyceridemia (HTG) is a feature of numerous metabolic disorders including dyslipidemias, metabolic syndrome, and diabetes mellitus type 2 and can increase the risk of premature coronary artery disease. HTG may also be due to genetic factors (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4cc8924804cfe95699805388c323fa
https://pubmed.ncbi.nlm.nih.gov/25580288

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