Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Olga Danov"'
Autor:
Jeff Bierwagen, Marie Wiegand, Katrin Laakmann, Olga Danov, Hannah Limburg, Stefanie Muriel Herbel, Thomas Heimerl, Jens Dorna, Danny Jonigk, Christian Preußer, Wilhelm Bertrams, Armin Braun, Katherina Sewald, Leon N. Schulte, Stefan Bauer, Elke Pogge von Strandmann, Eva Böttcher-Friebertshäuser, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs), which are important mediators of communication and pathogenesis. OMV uptake by host cells activates TLR signalling via transported PAMPs. As important reside
Externí odkaz:
https://doaj.org/article/5ab97f46113346758e29ef1c0e67adfd
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Objective Human precision cut lung slices (PCLS) are widely used as an ex vivo model system for drug discovery and development of new therapies. PCLS reflect the functional heterogeneity of lung tissue and possess relevant lung cell types. W
Externí odkaz:
https://doaj.org/article/df1941820c4948c99a39aaae49883e04
Competitive fitness of Pseudomonas aeruginosa isolates in human and murine precision-cut lung slices
Autor:
Nina Cramer, Marie Luise Nawrot, Lion Wege, Marie Dorda, Charline Sommer, Olga Danov, Sabine Wronski, Armin Braun, Danny Jonigk, Sebastian Fischer, Antje Munder, Burkhard Tümmler
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Chronic respiratory infections with the gram-negative bacterium Pseudomonas aeruginosa are an important co-morbidity for the quality of life and prognosis of people with cystic fibrosis (CF). Such long-term colonization, sometimes lasting up to sever
Externí odkaz:
https://doaj.org/article/3d4225000bcb47da80b9cc80b946cdcb
Autor:
Melissa Zimniak, Luisa Kirschner, Helen Hilpert, Nina Geiger, Olga Danov, Heike Oberwinkler, Maria Steinke, Katherina Sewald, Jürgen Seibel, Jochen Bodem
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
Abstract To circumvent time-consuming clinical trials, testing whether existing drugs are effective inhibitors of SARS-CoV-2, has led to the discovery of Remdesivir. We decided to follow this path and screened approved medications "off-label" against
Externí odkaz:
https://doaj.org/article/f67e6a08eef542cd9b92d04bc2ae89dd
Autor:
Olga Danov, Lisa Lasswitz, Helena Obernolte, Christina Hesse, Armin Braun, Sabine Wronski, Katherina Sewald
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Antiviral drugs such as rupintrivir may have an immune-modulatory effect in experimentally induced allergic asthma with subsequent RV infection. We infected lung slices of house-dust mite (HDM)-sensitized asthmatic mice ex vivo wi
Externí odkaz:
https://doaj.org/article/ecf8e131d6124229a7d57268618f6407
Autor:
Olga Danov, Martin Wolff, Sabine Bartel, Sebastian Böhlen, Helena Obernolte, Sabine Wronski, Danny Jonigk, Barbara Hammer, Draginja Kovacevic, Sebastian Reuter, Susanne Krauss-Etschmann, Katherina Sewald
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Smokers with apparently “healthy” lungs suffer from more severe and frequent viral respiratory infections, but the mechanisms underlying this observation are still unclear. Epithelial cells and dendritic cells (DC) form the first line of defense
Externí odkaz:
https://doaj.org/article/c05c48df982d41eaa4de4686b0618b76
Autor:
Olga Danov, Sharon Melissa Jiménez Delgado, Helena Obernolte, Sophie Seehase, Susann Dehmel, Peter Braubach, Hans-Gerd Fieguth, Gabriele Matschiner, Mary Fitzgerald, Danny Jonigk, Sascha Knauf, Olaf Pfennig, Gregor Warnecke, Judy Wichmann, Armin Braun, Katherina Sewald
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207767 (2018)
Subgroups of patients with severe asthma are insensitive to inhaled corticosteroids and require novel therapies on top of standard medical care. IL-13 is considered one of the key cytokines in the asthma pathogenesis, however, the effect of IL-13 was
Externí odkaz:
https://doaj.org/article/b147add0b8fb400793425ee3679fcfd7
Autor:
Lucie Sauerhering, Irina Kuznetsova, Alexandra Kupke, Lars Meier, Sandro Halwe, Cornelius Rohde, Jörg Schmidt, Rory E. Morty, Olga Danov, Armin Braun, István Vadász, Stephan Becker, Susanne Herold
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 205:964-968
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2aa13d7d50faee40328a25fc016472
https://doi.org/10.1164/rccm.202108-1830le
https://doi.org/10.1164/rccm.202108-1830le
Autor:
Nina, Cramer, Marie Luise, Nawrot, Lion, Wege, Marie, Dorda, Charline, Sommer, Olga, Danov, Sabine, Wronski, Armin, Braun, Danny, Jonigk, Sebastian, Fischer, Antje, Munder, Burkhard, Tümmler
Publikováno v:
Frontiers in cellular and infection microbiology. 12
Chronic respiratory infections with the gram-negative bacterium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f448fc97edd9740371733d1fcc7b47f6
https://pubmed.ncbi.nlm.nih.gov/36081773
https://pubmed.ncbi.nlm.nih.gov/36081773
Autor:
Katherina, Sewald, Olga, Danov
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2506
Viral infections are common causes of asthma exacerbations. To model these processes ex vivo, human precision-cut lung slices (PCLSs) can be used. Here we describe the infection of human PCLSs with the human influenza virus. We then provide methods t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::336c9f63b037aac75cb7ad53f3d32747
https://pubmed.ncbi.nlm.nih.gov/35771468
https://pubmed.ncbi.nlm.nih.gov/35771468