Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Olga Cumpelik"'
Publikováno v:
Carcinogenesis. 11(3)
Three major types of cell lines were distinguished according to their capacity for glutathione (GSH) conjugation of extracellularly generated benzo[alpha]pyrene (BaP) metabolites, and the level of DNA binding of such metabolites. (i) Cells, e.g. HepG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ff7e15cce40389335d3b6f2ef6ac0f
https://pubmed.ncbi.nlm.nih.gov/2311192
https://pubmed.ncbi.nlm.nih.gov/2311192
Publikováno v:
Nitroarenes ISBN: 9781461366942
We have assessed the cytotoxicity and genotoxicity of 1, 3-dinitropyrene (1, 3-DNP) and 1, 6-dinitropyrene (1, 6-DNP) in a panel of cell lines derived from various tissues of mouse, rat, hamster or man. The cell lines used were defined for their expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad02d205e328dc8cea59e6b76de95da
https://doi.org/10.1007/978-1-4615-3800-4_35
https://doi.org/10.1007/978-1-4615-3800-4_35
Publikováno v:
Environmental Health Perspectives
The effect of 2-aminofluorene (2-AF) on the toxicity of 2-aminoanthracene (2-AA) and 1,6-dinitropyrene (1,6-DNP) was studied in N-acetyltransferase-proficient V79-NHr1A2 cells genetically engineered for the expression of cytochrome P4501A2, and in wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953dfc1a53f86ba3364d871d8b684397
https://doi.org/10.2307/3432159
https://doi.org/10.2307/3432159
Publikováno v:
Xenobiotica. 18:747-755
1. The human lung tumour cells NCI-H322 metabolized benzo(a)pyrene (BP) at a rate of 160 pmol/10(6) cells/h for at least 8 h. About 30% of the total metabolites were water-soluble, 30% of which were conjugates with glutathione. The water-soluble frac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f84bebde6619f200353a5e82e081585
https://doi.org/10.3109/00498258809041713
https://doi.org/10.3109/00498258809041713
Publikováno v:
Carcinogenesis. 8:1051-1058
The study was aimed at determining the role of glutathione (GSH) conjugation in the binding of reactive benzo[a]pyrene (BaP) species to DNA of C3H/10T1/2 cells. In order to suppress GSH conjugation cells were depleted of GSH by treatment with buthion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa08c2b27f897e764a57d58fad7d04f1
https://doi.org/10.1093/carcin/8.8.1051
https://doi.org/10.1093/carcin/8.8.1051
The effect of cadmium and copper on monoamine oxidase type A and B in mitochondrial preparations from brain and liver was determined in vitro. The results showed a dose-related inhibition of the enzyme. Both the A and B forms of the enzyme were simil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cde7d3a36af478c068b1b25cf14bc22
http://edoc.hu-berlin.de/18452/10682
http://edoc.hu-berlin.de/18452/10682