Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Olga Brashavitskaya"'
Autor:
Carol J. Swallow, Anne-Claude Gingras, James W. Dennis, Roland Xu, Olga Brashavitskaya, Hannah Wu, Christopher Go, Karineh Kazazian
Summary of effect of Plk4 manipulation on change in centriole number, and on migration in wound healing assays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57881fdc4b03f1ea502a34b56d9df4a
https://doi.org/10.1158/0008-5472.22415625
https://doi.org/10.1158/0008-5472.22415625
Autor:
Carol J. Swallow, Anne-Claude Gingras, James W. Dennis, Roland Xu, Olga Brashavitskaya, Hannah Wu, Christopher Go, Karineh Kazazian
The polo family serine threonine kinase Plk4 has been proposed as a therapeutic target in advanced cancers based on increased expression in primary human cancers, facilitation of tumor growth in murine xenograft models, and centrosomal amplification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f970bd0faf9f6572abe6fbb3e1f5069
https://doi.org/10.1158/0008-5472.c.6509337
https://doi.org/10.1158/0008-5472.c.6509337
Autor:
Carol J. Swallow, Anne-Claude Gingras, James W. Dennis, Roland Xu, Olga Brashavitskaya, Hannah Wu, Christopher Go, Karineh Kazazian
Fig S7. Plk4 knockdown in MDA-MB-231, HeLa and MDA-MB-435 cancer cell lines. Fig S8. Plk4 interacts physically with Arp2. Fig S9. Arp2 regulates cancer cell spreading and migration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abaf5fb1ac70532ead0deea844c9611
https://doi.org/10.1158/0008-5472.22415634
https://doi.org/10.1158/0008-5472.22415634
Autor:
Carol J. Swallow, Anne-Claude Gingras, James W. Dennis, Roland Xu, Olga Brashavitskaya, Hannah Wu, Christopher Go, Karineh Kazazian
Supplementary Table 1. siRNA Supplementary Table 2. RT-PCR primers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76834becd80e2eea7a7093da6f569220
https://doi.org/10.1158/0008-5472.22415619.v1
https://doi.org/10.1158/0008-5472.22415619.v1
Autor:
Carol J. Swallow, Anne-Claude Gingras, James W. Dennis, Roland Xu, Olga Brashavitskaya, Hannah Wu, Christopher Go, Karineh Kazazian
Fig S1. Plk4 knockdown in cancer cell lines does not significantly alter viability or proliferation. Fig S2. Plk4 regulates cancer cell migration. Fig S3. Plk4 overexpression increases HeLa migration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a82c5fe9b53ff238ccd0f81d1d69d0
https://doi.org/10.1158/0008-5472.22415643.v1
https://doi.org/10.1158/0008-5472.22415643.v1
Autor:
Carol J. Swallow, Anne-Claude Gingras, James W. Dennis, Roland Xu, Olga Brashavitskaya, Hannah Wu, Christopher Go, Karineh Kazazian
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e6d7d11c20ab0145caf35ce16b5077
https://doi.org/10.1158/0008-5472.22415649
https://doi.org/10.1158/0008-5472.22415649
Autor:
Carol J. Swallow, Anne-Claude Gingras, James W. Dennis, Roland Xu, Olga Brashavitskaya, Hannah Wu, Christopher Go, Karineh Kazazian
Fig S4. Plk4 overexpression increases U2OS migration. Fig S5. Plk4 regulates HeLa invasion and spreading. Fig S6. Persistent Plk4 knockdown in MDA-MB-231 cells using a lentiviral shRNA system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6537918fdb4739b0a4a1a1f66634b05
https://doi.org/10.1158/0008-5472.22415637.v1
https://doi.org/10.1158/0008-5472.22415637.v1
Autor:
Carol J. Swallow, Anne-Claude Gingras, James W. Dennis, Roland Xu, Olga Brashavitskaya, Hannah Wu, Christopher Go, Karineh Kazazian
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b8b63a1285773a7db1065af797301a
https://doi.org/10.1158/0008-5472.22415631.v1
https://doi.org/10.1158/0008-5472.22415631.v1
Autor:
Kiera Lee, Karineh Kazazian, Marco Magalhaes, Olga Brashavitskaya, Savtaj S. Brar, Aiman A. Ali, Karina Pacholczyk, Deanna Ng, Carol J. Swallow, Shelly Luu
Publikováno v:
Journal of the American College of Surgeons. 233:e183
Autor:
Jennifer C. Macmillan, Francis S. W. Zih, Carol J. Swallow, Olga Brashavitskaya, Roland S. Z. Xu, Karineh Kazazian, Karina Pacholczyk, David Berger-Richardson
Publikováno v:
Current Colorectal Cancer Reports. 11:187-199
The five individual members of the mammalian polo-like kinase family play non-redundant roles in centriole replication and maturation, mitotic progression, cytokinesis, and the DNA damage response. In human colorectal cancer, Plk1 and Plk4 are expres