Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Olga Bobiļeva"'
Autor:
Francesco Nai, Maria Paula Flores Espinoza, Annalisa Invernizzi, Pablo Andrés Vargas-Rosales, Olga Bobileva, Marcin Herok, Amedeo Caflisch
Publikováno v:
ACS Bio & Med Chem Au, Vol 4, Iss 2, Pp 100-110 (2023)
Externí odkaz:
https://doaj.org/article/af72c61482884854bc1816e917c4c6da
Autor:
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kanepe, Anna L. Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
Publikováno v:
Molecules, Vol 28, Iss 2, p 768 (2023)
SARS-CoV-2 nsp14 guanine-N7-methyltransferase plays an important role in the viral RNA translation process by catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to viral mRNA cap. We report a structure-guided design and synthe
Externí odkaz:
https://doaj.org/article/c2d883e7fced4f05944731ebf536ab50
Autor:
Ma̅rtiņš Borodušķis, Anna Ramata-Stunda, Liene Patetko, Gints Kalniņš, Aigars Jirgensons, M. Sisovs, Kristaps Jaudzems, Kaspars Tars, Nils Rostoks, Olga Bobiļeva, Solveiga Grinberga, Raitis Bobrovs, Iveta Kaņepe, Anna L. Bula
Publikováno v:
ACS Medicinal Chemistry Letters
Viral mRNA cap methyltransferases (MTases) are emerging targets for the development of broad-spectrum antiviral agents. In this work, we designed potential SARS-CoV-2 MTase Nsp14 and Nsp16 inhibitors by using bioisosteric substitution of the sulfoniu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92550540e15b3506e3b8c315bd9cbcd
https://doi.org/10.1021/acsmedchemlett.1c00140
https://doi.org/10.1021/acsmedchemlett.1c00140
Autor:
Olga Bobiļeva, Einārs Loža
Publikováno v:
Chemistry of Heterocyclic Compounds. 54:1070-1074
The reaction of methyl 2-isothiocyanatobenzoate and 1-azido-3-(4-substituted phenyl)propan-2-ones in the presence of triphenyl phosphine in dioxane by heating produced tricyclic (Z)-2-(4-substituted benzylidene)-2,3-dihydro-5H-oxazolo[2,3-b]quinazoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f98087c18382baf3471dd89d9341638
https://doi.org/10.1007/s10593-018-2394-8
https://doi.org/10.1007/s10593-018-2394-8