Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Olga Bajenova"'
Autor:
Olga Bajenova, Anna Gorbunova, Igor Evsyukov, Michael Rayko, Svetlana Gapon, Ekaterina Bozhokina, Alexander Shishkin, Stephen J O'Brien
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161256 (2016)
Сarcinoembryonic antigen (CEA, CEACAM5, CD66) is a promoter of metastasis in epithelial cancers that is widely used as a prognostic clinical marker of metastasis. The aim of this study is to identify the network of genes that are associated with CEA
Externí odkaz:
https://doaj.org/article/72c27e12dc914564b92c5098365e925c
Autor:
Olga Bajenova, Alexey Tomilin, Stephen J. O'Brien, E. N. Tolkunova, Grigory Raskin, S. A. Koshkin, N. S. Petrov, Anna Danilova
Publikováno v:
Tumor Biology. 37:12833-12842
The principal cause of death in cancer involves tumor progression and metastasis. Since only a small proportion of the primary tumor cells, cancer stem cells (CSCs), which are the most aggressive, have the capacity to metastasize and display properti
Autor:
Mikhail Liskovykh, Alexey Tomilin, A. P. Davydov-Sinitsyn, Rashida Orlova, S. A. Koshkin, Olga Bajenova, S. V. Ponomartsev, I. V. Rykov, E. N. Tolkunova
Publikováno v:
Cell and Tissue Biology. 9:318-325
Previously, we have described the establishment of a subpopulation of cancer stem cells from the human colorectal carcinoma cell line MIP101. These cells exhibit enhanced clonogenic and tumorigenic capacities. Depletion of the stem compartment in the
Autor:
Alexey Tomilin, Olga Bajenova, E. N. Tolkunova, Sergey V. Malov, Peter Thomas, S. A. Koshkin, Stephen J. O'Brien
Publikováno v:
Journal of Integrative Oncology.
Clinical and experimental data suggest that carcinoembryonic antigen (CEA, CD66e, CEACAM-5) plays a key role in the formation of hepatic metastasis from colorectal and other types of epithelial cancers. The molecular events involved in CEA-induced me
Autor:
Alexey Tomilin, Olga Bajenova, Mikhail Liskovykh, E. N. Tolkunova, S. V. Ponomartsev, A. P. Davydov-Sinitsyn, L. L. Chechik
Publikováno v:
Cell and Tissue Biology. 7:407-416
The present work is an attempt to compare cancer cells of the same origin but differing in the expression of CEA protein, a clinical marker of metastatic carcinomas. CEA, presumably, is one of the key factors in metastatic activity. We investigated t
Autor:
Stephen J. O'Brien, Anna Gorbunova, Michael Rayko, Igor Evsyukov, Olga Bajenova, Ekaterina Bozhokina, Svetlana Gapon, Alexander A. Shishkin
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161256 (2016)
PLoS ONE
PLoS ONE
Сarcinoembryonic antigen (CEA, CEACAM5, CD66) is a promoter of metastasis in epithelial cancers that is widely used as a prognostic clinical marker of metastasis. The aim of this study is to identify the network of genes that are associated with CEA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d56ede877039b3b7f4d53eb800a9a4
https://resolver.caltech.edu/CaltechAUTHORS:20160913-090623240
https://resolver.caltech.edu/CaltechAUTHORS:20160913-090623240
Publikováno v:
Clinical & Experimental Metastasis. 28:923-932
This article discusses the role of carcinoembryonic antigen (CEA) as a facilitator of the inflammatory response and its effect on colorectal cancer hepatic metastasis. Colorectal cancer accounts for 11% of all cancers in the United States and the maj
Autor:
Runna Moussa, R. Armour Forse, Peter A. Burke, Donald A. Lazure, Peter Thomas, Aniruddha Ganguly, Olga Bajenova
Publikováno v:
Journal of Endotoxin Research. 12:352-357
Using a combination of gel-exclusion chromatography and ligand binding with [125I]-lipopolysaccharide (LPS), we discovered two novel endotoxin-binding proteins, p31LPB and p34LPB, in Kupffer cells. Their molecular masses suggest that these are previo
Publikováno v:
Experimental Cell Research. 291:228-241
Elevated concentrations of carcinoembryonic antigen (CEA) in the blood are associated with the development of hepatic metastases from colorectal cancers. Clearance of circulating CEA occurs through endocytosis by liver macrophages, Kupffer cells. Pre
Autor:
Regis Zimmer, John Salisbury-Rowswell, Olga Bajenova, Peter Thomas, Eugenia Stolper, Afshan Nanji
Publikováno v:
Journal of Biological Chemistry. 276:31067-31073
Here we report the isolation of the recombinant cDNA clone from rat macrophages, Kupffer cells (KC) that encodes a protein interacting with carcinoembryonic antigen (CEA). To isolate and identify the CEA receptor gene we used two approaches: screenin